Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Noa B. Martin-Cofreces"'
Autor:
Rebeca Martínez-Hernández, Ana Serrano-Somavilla, Ana Ramos-Leví, Miguel Sampedro-Nuñez, Alberto Lens-Pardo, José Luis Muñoz De Nova, Juan Carlos Triviño, María Ujue González, Lorena Torné, Javier Casares-Arias, Noa B. Martín-Cófreces, Francisco Sánchez-Madrid, Mónica Marazuela
Publikováno v:
EBioMedicine, Vol 50, Iss , Pp 329-342 (2019)
Background: The mechanisms underlying autoimmune thyroid disease (AITD) remain elusive. Identification of such mechanisms would reveal novel and/or better therapeutic targets. Here, we use integrated analysis of miRNAs and mRNAs expression profiling
Externí odkaz:
https://doaj.org/article/09d67af173a4455ba2be8e98d6bd9d03
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8, p 2859 (2020)
The immune synapse (IS) is a well-known intercellular communication platform, organized at the interphase between the antigen presenting cell (APC) and the T cell. After T cell receptor (TCR) stimulation, signaling from plasma membrane proteins and l
Externí odkaz:
https://doaj.org/article/096add112e644386a9202a8ce544f435
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/13375ffbe436493d8eb6976303265725
Autor:
Álvaro Gómez-Morón, Silvia Requena, Clara Pertusa, Marta Lozano-Prieto, Diego Calzada-Fraile, Camila Scagnetti, Inés Sánchez-García, Ana Adela Calero-García, Manuel Izquierdo, Noa B. Martín-Cófreces
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The organization of the mitochondrial network is relevant for the metabolic fate of T cells and their ability to respond to TCR stimulation. This arrangement depends on cytoskeleton dynamics in response to TCR and CD28 activation, which allows the po
Externí odkaz:
https://doaj.org/article/24771d46be214bd3bb8dcf0742bda716
Autor:
Amelia Rojas‐Gómez, Sara G. Dosil, Francisco J. Chichón, Nieves Fernández‐Gallego, Alessia Ferrarini, Enrique Calvo, Diego Calzada‐Fraile, Silvia Requena, Joaquin Otón, Alvaro Serrano, Rocio Tarifa, Montserrat Arroyo, Andrea Sorrentino, Eva Pereiro, Jesus Vázquez, José M. Valpuesta, Francisco Sánchez‐Madrid, Noa B. Martín‐Cófreces
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 6, Pp n/a-n/a (2023)
Abstract Cell proteostasis includes gene transcription, protein translation, folding of de novo proteins, post‐translational modifications, secretion, degradation and recycling. By profiling the proteome of extracellular vesicles (EVs) from T cells
Externí odkaz:
https://doaj.org/article/92e772c6f8d44bdbb9870fce780f13ea
Autor:
Noelia Blas-Rus, Eugenio Bustos-Morán, Ignacio Pérez de Castro, Guillermo de Cárcer, Aldo Borroto, Emilio Camafeita, Inmaculada Jorge, Jesús Vázquez, Balbino Alarcón, Marcos Malumbres, Noa B. Martín-Cófreces, Francisco Sánchez-Madrid
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Aurora A is a protein kinase that contributes to the progression of mitosis by stimulating microtubule nucleation. Here the authors show that Aurora A also functions during T cell activation by maintaining TCR signaling through Lck activation.
Externí odkaz:
https://doaj.org/article/70cde4b8e22c4dcfa69bb2d3c104caa9
Autor:
Álvaro Gómez-Morón, Ilya Tsukalov, Camila Scagnetti, Clara Pertusa, Marta Lozano-Prieto, Pedro Martínez-Fleta, Silvia Requena, Pilar Martín, Aranzazu Alfranca, Enrique Martin-Gayo, Noa B Martin-Cofreces
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionCD8+ cytotoxic T lymphocytes (CTLs) are highly effective in defending against viral infections and tumours. They are activated through the recognition of peptide–MHC-I complex by the T-cell receptor (TCR) and co-stimulation. This cognat
Externí odkaz:
https://doaj.org/article/0ac181f7f4fc4d9c8e1b085025124003
Autor:
Gioia Boncompagni, Vanessa Tatangelo, Ludovica Lopresti, Cristina Ulivieri, Nagaja Capitani, Carmela Tangredi, Francesca Finetti, Giuseppe Marotta, Federica Frezzato, Andrea Visentin, Sara Ciofini, Alessandro Gozzetti, Monica Bocchia, Diego Calzada-Fraile, Noa B. Martin Cofreces, Livio Trentin, Laura Patrussi, Cosima T. Baldari
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-13 (2024)
Abstract The tumor microenvironment (TME) plays a central role in the pathogenesis of chronic lymphocytic leukemia (CLL), contributing to disease progression and chemoresistance. Leukemic cells shape the TME into a pro-survival and immunosuppressive
Externí odkaz:
https://doaj.org/article/d642398d0f0d48b38f301e377350c763