Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Noëlle, Callizot"'
Autor:
Maria Fazzari, Giulia Lunghi, Alexandre Henriques, Noëlle Callizot, Maria Grazia Ciampa, Laura Mauri, Simona Prioni, Emma Veronica Carsana, Nicoletta Loberto, Massimo Aureli, Luigi Mari, Sandro Sonnino, Elena Chiricozzi, Erika Di Biase
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1305 (2023)
Past evidence has shown that the exogenous administration of GM1 ganglioside slowed neuronal death in preclinical models of Parkinson’s disease, a neurodegenerative disorder characterized by the progressive loss of dopamine-producing neurons: howev
Externí odkaz:
https://doaj.org/article/8a1943fc716f42f4923a8d9f878d1326
Autor:
Serguei, Nabirotchkin, Jan, Bouaziz, Fabrice, Glibert, Jonas, Mandel, Julie, Foucquier, Rodolphe, Hajj, Noëlle, Callizot, Nathalie, Cholet, Mickaël, Guedj, Daniel, Cohen
Publikováno v:
Journal of Alzheimer's Disease. 88:1585-1603
Background: Human diseases are multi-factorial biological phenomena resulting from perturbations of numerous functional networks. The complex nature of human diseases explains frequently observed marginal or transitory efficacy of mono-therapeutic in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3689c941909510a2251ed0bd5d8421b6
https://doi.org/10.3233/jad-220120
https://doi.org/10.3233/jad-220120
Autor:
Alexandra Bouscary, Cyril Quessada, Althéa Mosbach, Noëlle Callizot, Michael Spedding, Jean-Philippe Loeffler, Alexandre Henriques
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Amyotrophic lateral sclerosis (ALS) is a multifactorial and fatal neurodegenerative disease. Growing evidence connects sphingolipid metabolism to the pathophysiology of ALS. In particular, levels of ceramides, glucosylceramides, and gangliosides are
Externí odkaz:
https://doaj.org/article/337e1ace11764decac5e777520b50712
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215277 (2019)
Most of the Parkinson's disease (PD) cases are sporadic, although several genes are directly related to PD. Several pathways are central in PD pathogenesis: protein aggregation linked to proteasomal impairments, mitochondrial dysfunctions and impairm
Externí odkaz:
https://doaj.org/article/7744094ecd4f41b3a88ec47efce16a38
Autor:
Zixin Wang, Alexandre Henriques, Laura Rouvière, Noëlle Callizot, Lin Tan, Michael T. Hotchkin, Rodrigue Rossignol, Mark G. Mortenson, Karen S. Ho, Hui Wang
Bioenergetic deficits, such as mitochondrial impairments and dysfunction in glucose metabolism, have been identified as significant contributors to neurodegenerative diseases. Nevertheless, identifying safe and effective means to address intracellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44c65e7412c38818596575d98ee17902
https://doi.org/10.1101/2023.05.08.539856
https://doi.org/10.1101/2023.05.08.539856
Autor:
Sighild Lemarchant, Mélissa Sourioux, Juliette Le Douce, Alexandre Henriques, Noëlle Callizot, Sandrine Hugues, Mélissa Farinelli, Yann Godfrin
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 8867
NX210c is a disease-modifying dodecapeptide derived from the subcommissural organ-spondin that is under preclinical and clinical development for the treatment of neurological disorders. Here, using whole-cell patch-clamp recordings, we demonstrate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eff20d401d592c2a0d4c604fd3af06a
https://pubmed.ncbi.nlm.nih.gov/36012124
https://pubmed.ncbi.nlm.nih.gov/36012124
Publikováno v:
Neuroscience. 463
Subcommissural organ (SCO)-spondin is a brain-specific glycoprotein produced during embryogenesis, that strongly contributes to neuronal development. The SCO becomes atrophic in adults, halting SCO-spondin production and its neuroprotective functions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bafc9faeb8191974c02ef888e0aaeda
https://pubmed.ncbi.nlm.nih.gov/33577953
https://pubmed.ncbi.nlm.nih.gov/33577953
Publikováno v:
European Journal of Pharmacology. 539:64-70
Lacosamide was tested in the streptozotocin rat model of diabetic neuropathic pain in comparison to drugs which are commonly used in the treatment of diabetic neuropathic pain, i.e. antidepressants and anticonvulsants. In diabetic rats, lacosamide at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3b7f3ac451e53208278c30d27f1e53
https://doi.org/10.1016/j.ejphar.2006.04.009
https://doi.org/10.1016/j.ejphar.2006.04.009
Autor:
Noëlle Callizot, Petra Beranova, Karel Chalupsky, Christa Schott, Jean-Claude Stoclet, Bernard Muller, Jean-Luc Boucher, G. Entlicher, Petr Vetrovsky, Daniel Mansuy
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 303:823-830
The mechanisms of vasorelaxation elicited by N(omega)-hydroxy-L-arginine (L-NOHA) and other compounds bearing a C=NOH function and the structural determinants governing this effect were investigated in rat aorta. L-NOHA, formamidoxime, five aromatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00abe5b3020d3f5a609e31af11d9824c
https://doi.org/10.1124/jpet.102.038612
https://doi.org/10.1124/jpet.102.038612
Autor:
Colette Hindelang, Jean-Louis Mandel, Aurora Pujol, Udo Bartsch, Noëlle Callizot, Melitta Schachner
Publikováno v:
Human Molecular Genetics. 11:499-505
Adrenomyeloneuropathy (AMN) and cerebral childhood adrenoleukodystrophy (CCALD) are the main phenotypic variants of an X-linked inherited metabolic disorder causing demyelination, X-linked adrenoleukodystrophy (X-ALD). It is caused by mutations in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb9347b19b9c8a75795793da644675dd
https://doi.org/10.1093/hmg/11.5.499
https://doi.org/10.1093/hmg/11.5.499