Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Noël, Pinaud"'
Publikováno v:
European Radiology Experimental, Vol 8, Iss 1, Pp 1-12 (2024)
Abstract Background Longitudinal T1 relaxation time is a key imaging biomarker. In addition, T1 values are modulated by the administration of T1 contrast agents used in patients with tumors and metastases. However, in clinical practice, dedicated T1
Externí odkaz:
https://doaj.org/article/fbb5f7203aed48bf92cb870e7e873138
Autor:
Sandra Albenque-Rubio, Jean Guillon, Patrice Agnamey, Céline Damiani, Solène Savrimoutou, Romain Mustière, Noël Pinaud, Stéphane Moreau, Jean-Louis Mergny, Luisa Ronga, Ioannis Kanavos, Mathieu Marchivie, Serge Moukha, Pascale Dozolme, Pascal Sonnet, Anita Cohen
Publikováno v:
Drugs and Drug Candidates, Vol 3, Iss 3, Pp 615-637 (2024)
By taking into account our previously described series of 1,3,5-tris[(4-(substituted-aminomethyl)phenyl)methyl]benzene compounds, we have now designed, prepared, and evaluated in vitro against Plasmodium falciparum a novel series of structural analog
Externí odkaz:
https://doaj.org/article/9dd6625364864c06b8baee9fd5429344
Publikováno v:
Molbank, Vol 2024, Iss 3, p M1849 (2024)
Bis(1-butyl-1-methypyrrolidinium) perthiodicarbonate was obtained by the reaction of carbon disulfide with 1-butyl-1-methypyrrolidinium acetate ([BmPyrro][Ac]) in the liquid phase. Structural characterization of this original complex was achieved by
Externí odkaz:
https://doaj.org/article/11c8c864578347c3980f04d6d2166a96
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The evaluation of the efficacy of a drug is a fundamental step in the development of new treatments or in personalized therapeutic strategies and patient management. Ideally, this evaluation should be rapid, possibly in real time, easy to pe
Externí odkaz:
https://doaj.org/article/4229092146cf4cd7837e9c088de38160
Autor:
Camille Blouet, Stéphanie Letast, Thomas Robert, Stéphane Bach, Noël Pinaud, Nicolas Joubert, Marie-Claude Viaud-Massuard, Jean Guillon, Cédric Logé, Caroline Denevault-Sabourin
Publikováno v:
Molbank, Vol 2023, Iss 4, p M1735 (2023)
Potassium 6-oxo-7,13,16,22-tetraazatetracyclo[12.6.2.18,12.017,21]tricosa-1(20),8(23),9,11,14,16,18,21-octaen-2-yne-15-carboxylate was synthesized through a multi-step pathway, starting from commercially available 3-iodo-1,2-phenylenediamine. Structu
Externí odkaz:
https://doaj.org/article/eb3c8596c9f24290a70b6f4142e78806
Autor:
Jean Guillon, Solène Savrimoutou, Sandra Albenque-Rubio, Noël Pinaud, Nina Fillová, Stéphane Moreau, Virginie Baylot, Vanessa Desplat
Publikováno v:
Molbank, Vol 2023, Iss 3, p M1691 (2023)
(E)-Pyrrolo[1,2-a]quinoxalin-4-yl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one was designed then synthesized using a multi-step pathway starting from commercially available 2-nitroaniline. Structure characterization of this original substituted pyrrolo
Externí odkaz:
https://doaj.org/article/c1eabcf83bb74f1c95a92b77a720eee0
Autor:
Jean Guillon, Marc Le Borgne, Vittoria Milano, Aurore Guédin-Beaurepaire, Stéphane Moreau, Noël Pinaud, Luisa Ronga, Solène Savrimoutou, Sandra Albenque-Rubio, Mathieu Marchivie, Haouraa Kalout, Charley Walker, Louise Chevallier, Corinne Buré, Eric Largy, Valérie Gabelica, Jean-Louis Mergny, Virginie Baylot, Jacky Ferrer, Yamina Idrissi, Edith Chevret, David Cappellen, Vanessa Desplat, Zsuzsanna Schelz, István Zupkó
Publikováno v:
Pharmaceuticals, Vol 17, Iss 1, p 30 (2023)
The syntheses of novel 2,4-bis[(substituted-aminomethyl)phenyl]phenylquinazolines 12 and 2,4-bis[(substituted-aminomethyl)phenyl]phenylquinolines 13 are reported here in six steps starting from various halogeno-quinazoline-2,4-(1H,3H)-diones or subst
Externí odkaz:
https://doaj.org/article/a1792b25a47e4834a049e8058f8ad1b4
Autor:
Jean Guillon, Solène Savrimoutou, Sandra Albenque-Rubio, Noël Pinaud, Stéphane Moreau, Vanessa Desplat
Publikováno v:
Molbank, Vol 2022, Iss 1, p M1333 (2022)
1,3-Dihydro-1-{1-[4-(4-phenylpyrrolo[1,2-a]quinoxalin-3-yl)benzyl]piperidin-4-yl}-2H-benzimidazol-2-one has been synthesized through a multi-step pathway starting from commercially available 2-nitroaniline. A structure characterization of this new su
Externí odkaz:
https://doaj.org/article/7adc9c79eee0415ebb4f680ecb1fe379
Autor:
Jean Guillon, Solène Savrimoutou, Sandra Rubio, Stéphane Moreau, Noël Pinaud, Mathieu Marchivie, Vanessa Desplat
Publikováno v:
Molbank, Vol 2020, Iss 1, p M1113 (2020)
1-Phenyl-8-[[4-(pyrrolo[1,2-a]quinoxalin-4-yl)phenyl]methyl]-1,3,8-triazaspiro[4.5]decan-4-one has been successfully synthesized via a multi-step pathway starting from 2-nitroaniline. Structure characterization of this original pyrrolo[1,2-a]quinoxal
Externí odkaz:
https://doaj.org/article/7af8c00ab5ba45e4a462029a296aad95
Autor:
Yannick Crémillieux, Ursule Dumont, Leslie Mazuel, Roberto Salvati, Vanessa Zhendre, Silvia Rizzitelli, Jordy Blanc, Hélène Roumes, Noël Pinaud, Anne-Karine Bouzier-Sore
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
The dynamic in vivo profiling of lactate is of uppermost importance in both neuroenergetics and neuroprotection fields, considering its central suspected role as a metabolic and signaling molecule. For this purpose, we implemented proton magnetic res
Externí odkaz:
https://doaj.org/article/7b97b4192be349f0b49aab809440a791