Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Noémi Bózsity"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 7, Pp 6566-6579 (2024)
Cervical cancer presents a significant challenge to the global health of women. Despite substantial advances in human papillomavirus (HPV)-related cervical cancer vaccines, non-HPV-related cervical cancer is still waiting novel therapeutic options. D
Externí odkaz:
https://doaj.org/article/c2806ffeb76142258c598715ff3bb3ae
Autor:
Nikoletta Szemerédi, Zsuzsanna Schelz, Dária Antónia Horvath, Bálint Rácz, András G. Szatmári, Hiba F. Muddather, Noémi Bózsity, István Zupkó, Gabriella Spengler
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 877 (2024)
Chemotherapy is a known treatment modality that improves the long-term survival of breast cancer patients. However, due to the resistance to numerous anticancer drugs, alternative chemotherapeutic strategies are required. Regarding antimetabolic drug
Externí odkaz:
https://doaj.org/article/9e6f2b925ffb49268430c49ee94d86f3
Autor:
Isaac Kinyua Njangiru, Noémi Bózsity-Faragó, Vivien Erzsébet Resch, Gábor Paragi, Éva Frank, György T. Balogh, István Zupkó, Renáta Minorics
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 622 (2024)
The clinical application of 2-methoxyestradiol (2ME) in cancer therapy has been limited by its low solubility and rapid metabolism. Derivatives of 2ME have been synthesised to enhance bioavailability and decrease hepatic metabolism. Compound 4a, an a
Externí odkaz:
https://doaj.org/article/afb882dda7f946a8b6d7d0873b560d71
Autor:
Noémi Bózsity, Viktória Nagy, Johanna Szabó, Balázs Pálházi, Zoltán Kele, Vivien Resch, Gábor Paragi, István Zupkó, Renáta Minorics, Erzsébet Mernyák
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4274 (2024)
Directed structural modifications of natural products offer excellent opportunities to develop selectively acting drug candidates. Natural product hybrids represent a particular compound group. The components of hybrids constructed from different mol
Externí odkaz:
https://doaj.org/article/cdf80854a1f5439bad03d3851450f7a1
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 262 (2024)
Starting from isosteviol, a series of diterpenoid 1,3-aminoalcohol derivatives were prepared via stereoselective transformations. The acid-catalysed hydrolysis and rearrangement of natural stevioside produced isosteviol, which was transformed into th
Externí odkaz:
https://doaj.org/article/ceba688d29ac494b806099d0ba6fd7ee
Autor:
Ranim Saker, Orsolya Jójárt-Laczkovich, Géza Regdon, Tamás Takács, Imre Szenti, Noémi Bózsity-Faragó, István Zupkó, Tamás Sovány
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2780 (2023)
Nanotechnology is playing a significant role in modern life with tremendous potential and promising results in almost every domain, especially the pharmaceutical one. The impressive performance of nanomaterials is shaping the future of science and re
Externí odkaz:
https://doaj.org/article/9785521bd1474eba8a79098119f7fba6
Autor:
Tibor Kovács, Ildikó Lajter, Norbert Kúsz, Zsuzsanna Schelz, Noémi Bózsity-Faragó, Anikó Borbás, István Zupkó, Georg Krupitza, Richard Frisch, Judit Hohmann, Andrea Vasas, Attila Mándi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5841 (2023)
A new flexible germacranolide (1, lobatolide H) was isolated from the aerial parts of Neurolaena lobata. The structure elucidation was performed by classical NMR experiments and DFT NMR calculations. Altogether, 80 theoretical level combinations with
Externí odkaz:
https://doaj.org/article/5ed48aedc1494b92b2f5642bd8ce85ca
Autor:
Andrea Vasas, Ildikó Lajter, Norbert Kúsz, Sándor Balázs Király, Tibor Kovács, Tibor Kurtán, Noémi Bózsity, Nikolett Nagy, Zsuzsanna Schelz, István Zupkó, Georg Krupitza, Richard Frisch, Attila Mándi, Judit Hohmann
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2088 (2021)
Seven new germacranolides (1–3, 5–8), among them a heterodimer (7), and known germacranolide (4), eudesmane (9) and isodaucane (10) sesquiterpenes were isolated from the aerial parts of Neurolaena lobata. Their structures were determined by using
Externí odkaz:
https://doaj.org/article/8391bce051864767a1ad7980e632055a
Autor:
Johanna Szabó, Nóra Jerkovics, Gyula Schneider, János Wölfling, Noémi Bózsity, Renáta Minorics, István Zupkó, Erzsébet Mernyák
Publikováno v:
Molecules, Vol 21, Iss 5, p 611 (2016)
The syntheses of C-13 epimeric 3-[(1-benzyl-1,2,3-triazol-4-yl)methoxy]-d-secoestrones are reported. Triazoles were prepared from 3-(prop-2-inyloxy)-d-secoalcohols and p-substituted benzyl azides via Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC)
Externí odkaz:
https://doaj.org/article/6e11a2e81c184b0b8ffcfb371b069913
Autor:
Imre Ocsovszki, Vasilissa Manova, Maria Krasteva, Mariyana Georgieva, István Zupkó, Zlatina Gospodinova, Svetla Todinova, Noémi Bózsity, Stefka G. Taneva
Publikováno v:
Zeitschrift für Naturforschung C. 76:129-140
Current plant-derived anticancer therapeutics aim to reach higher effectiveness, to potentiate chemosensitivity and minimize the toxic side effects compared to conventional chemotherapy. Cotinus coggygria Scop. is a herb with high pharmacological pot