Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Nnamdi M Ikeogu"'
Autor:
Chidalu A. Edechi,, Nnamdi M. Ikeogu, Lucas Evangelista de Lima Terceiro, Jude E. Uzonna, Yvonne Myal
Publikováno v:
European Medical Journal, Vol 5, Iss 3, Pp 55-62 (2020)
The underlying mechanisms of metastasis in patients with breast cancer is still poorly understood. Approximately 6% of patients with breast cancer present with metastasis at the time of diagnosis. Metastatic breast cancer is difficult to treat and pa
Externí odkaz:
https://doaj.org/article/84c70025a8294d27af0b54cbafdfb5f9
Autor:
Chidalu A. Edechi, Nnamdi M. Ikeogu, Gloria N. Akaluka, Lucas E. L. Terceiro, Mikayla Machado, Enitan S. Salako, Aida F. Barazandeh, Sam K. P. Kung, Jude E. Uzonna, Yvonne Myal
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The prolactin inducible protein (PIP) is expressed to varying degrees in more than 90% of breast cancers (BCs). Although high levels of PIP expression in BC has been shown to correlate with better prognosis and patient response to chemotherapy, some
Externí odkaz:
https://doaj.org/article/f36d7e051a3241f6ba0361ac678aade6
Autor:
Nnamdi M. Ikeogu, Gloria N. Akaluka, Chidalu A. Edechi, Enitan S. Salako, Chukwunonso Onyilagha, Aida F. Barazandeh, Jude E. Uzonna
Publikováno v:
Microorganisms, Vol 8, Iss 8, p 1201 (2020)
Parasitic diseases still constitute a major global health problem affecting billions of people around the world. These diseases are capable of becoming chronic and result in high morbidity and mortality. Worldwide, millions of people die each year fr
Externí odkaz:
https://doaj.org/article/d5a70b2bc25049a3a66d7d9706f1c0ef
Autor:
Aaron J. Marshall, Greg Matlashewski, Aida F. Barazandeh, Grant M. Hatch, Chidalu A Edechi, Edgard M. Mejia, Zhirong Mou, Wen-Wei Zhang, Javad Alizadeh, Nnamdi M Ikeogu, Saeid Ghavami, Jude E. Uzonna
Publikováno v:
The Journal of Immunology. 206:1013-1026
There is currently no effective vaccine against leishmaniasis because of the lack of sufficient knowledge about the Ags that stimulate host-protective and long-lasting T cell–mediated immunity. We previously identified Leishmania phosphoenolpyruvat
Autor:
Somtochukwu S Onwah, Chidalu A Edechi, Ping Jia, Abdelilah S. Gounni, Chukuwunonso Onyilagha, Nnamdi M Ikeogu, Enitan S Salako, Gloria N Akaluka, Romaniya Zayats, Aida Feiz-Barazandeh, Zhirong Mou, Lianyu Shan, Jude E. Uzonna, Thomas T. Murooka
Publikováno v:
The Journal of Immunology. 206:588-598
Protective immunity to cutaneous leishmaniasis is mediated by IFN-γ–secreting CD4+ Th1 cells. IFN-γ binds to its receptor on Leishmania-infected macrophages, resulting in their activation, production of NO, and subsequent destruction of parasites
Autor:
Hiroyuki Kishi, Nnamdi M Ikeogu, Aida F. Barazandeh, Gaurav Gupta, Zhirong Mou, Xiaoping Zhang, Chukwunonso Onyilagha, Hiroshi Hamana, Ping Jia, Jude E. Uzonna
Publikováno v:
The Journal of Immunology. 205:1355-1364
There is currently no clinically effective vaccine against cutaneous leishmaniasis because of poor understanding of the Ags that elicit protective CD4+ T cell immunity. In this study, we identified a naturally processed peptide (DLD63–79) that is d
Autor:
Yang Xin Zi Xu, Sudharsana Rao Ande, Nnamdi M. Ikeogu, Kecheng Zhou, Jude E. Uzonna, Suresh Mishra
Publikováno v:
Molecular immunology. 144
Immunometabolism plays a crucial role in the activation and functional plasticity of immune cells, which in large determines a variety of health and disease states. Factors that integrate immunometabolism in immune cell signaling and functions are be
Publikováno v:
The Journal of Immunology. 203:964-971
NK cells are key innate immune cells that play critical roles in host defense. Although NK cells have been shown to regulate immunity to some infectious diseases, their role in immunity to Trypanosoma congolense has not been investigated. NK cells ar
Autor:
Chidalu A. Edechi, Nnamdi M. Ikeogu, Gloria N. Akaluka, Lucas E. L. Terceiro, Mikayla Machado, Enitan S. Salako, Aida F. Barazandeh, Sam K. P. Kung, Jude E. Uzonna, Yvonne Myal
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology, Vol 11 (2021)
The prolactin inducible protein (PIP) is expressed to varying degrees in more than 90% of breast cancers (BCs). Although high levels of PIP expression in BC has been shown to correlate with better prognosis and patient response to chemotherapy, some
Autor:
Nnamdi M, Ikeogu, Chidalu A, Edechi, Gloria N, Akaluka, Aida, Feiz-Barazandeh, Jude E, Uzonna
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2184
The isolation of immune cells from the bone marrow is important for obtaining sufficient numbers for downstream analysis. Immune cells derived from the bone marrow may be subjected to metabolic assays for analysis or used to test the effect of infect