Zobrazeno 1 - 10 of 153 pro vyhledávání: '"Nkh de Boer"'
1
Biotransformation of 6-thioguanine in inflammatory bowel disease patients: a comparison of oral and intravenous administration of 6-thioguanine
Autor: Cjj Mulder, G.J. Peters, René M. Vos, A.A. van Bodegraven, Bindia Jharap, Abraham J. Wilhelm, Nkh de Boer, A. Zwiers, Kees Smid
Publikováno v: British Journal of Pharmacology. 163:722-731
BACKGROUND AND PURPOSE Although 6-mercaptopurine and azathioprine are effective treatments in inflammatory bowel disease (IBD), many patients discontinue treatment because of side effects. 6-Thioguanine (6-TG) may be an alternative rescue therapy in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::46d16d67ded3aeb1754fc441bb84d7f3
https://doi.org/10.1111/j.1476-5381.2011.01265.x
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2
Influence of 5-aminosalicylic acid on 6-thioguanosine phosphate metabolite levels: a prospective study in patients under steady thiopurine therapy
Autor: Nkh de Boer, Wong, P. M. Hooymans, S Karner, Cjj Mulder, A.A. van Bodegraven, Matthias Schwab, Bindia Jharap, P. de Graaf, AI Veldkamp
Publikováno v: British Journal of Pharmacology. 160:1083-1091
Background and purpose: 5-aminosalicylate (5-ASA) raises levels of 6-thioguanine nucleotides (6-TGN), the active metabolites of thiopurines such as azathioprine (AZA). Changes in levels of each individual TGN – 6-thioguanosine mono-, di- and tripho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::998cf7a45a8bbc52f34194005e5a195a
https://doi.org/10.1111/j.1476-5381.2010.00731.x
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4
Akademický článek
Detecting Colorectal Neoplasia Using Specific Fecal Fluorogenic Protease-Sensitive Substrates: A Pilot Study.
Autor: Opperman RCM; Department of Gastroenterology and Hepatology, Amsterdam UMC, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism (AGEM) Research Institute, 1081 HV Amsterdam, The Netherlands.; Research Program, Cancer Center Amsterdam, 1081 HV Amsterdam, The Netherlands., Bosch S; Department of Gastroenterology and Hepatology, Amsterdam UMC, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism (AGEM) Research Institute, 1081 HV Amsterdam, The Netherlands., Nazmi K; Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam and VU University Amsterdam, Gustav Mahlerlaan 3004, 1081 LA Amsterdam, The Netherlands., Bikker FJ; Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam and VU University Amsterdam, Gustav Mahlerlaan 3004, 1081 LA Amsterdam, The Netherlands., Brand HS; Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam and VU University Amsterdam, Gustav Mahlerlaan 3004, 1081 LA Amsterdam, The Netherlands., Jimenez CR; Research Program, Cancer Center Amsterdam, 1081 HV Amsterdam, The Netherlands.; Department of Medical Oncology, Amsterdam UMC, VU University Medical Center, 1081 HV Amsterdam, The Netherlands., de Meij TGJ; Amsterdam Gastroenterology Endocrinology Metabolism (AGEM) Research Institute, 1081 HV Amsterdam, The Netherlands.; Department of Pediatric Gastroenterology, Emma Children's Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.; Department of Pediatric Gastroenterology, Emma Children's Hospital, Amsterdam UMC, Academic Medical Centre, 1105 AZ Amsterdam, The Netherlands., Dekker E; Amsterdam Gastroenterology Endocrinology Metabolism (AGEM) Research Institute, 1081 HV Amsterdam, The Netherlands.; Research Program, Cancer Center Amsterdam, 1081 HV Amsterdam, The Netherlands.; Department of Gastroenterology and Hepatology, Amsterdam UMC, University of Amsterdam, 1081 HV Amsterdam, The Netherlands., de Boer NKH; Department of Gastroenterology and Hepatology, Amsterdam UMC, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism (AGEM) Research Institute, 1081 HV Amsterdam, The Netherlands., Kaman WE; Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam and VU University Amsterdam, Gustav Mahlerlaan 3004, 1081 LA Amsterdam, The Netherlands.
Publikováno v: Analytical chemistry [Anal Chem] 2024 Dec 12. Date of Electronic Publication: 2024 Dec 12.
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5
Akademický článek
Early therapeutic drug monitoring helps to identify inflammatory bowel disease patients with a high risk to fail thiopurine treatment.
Autor: Deben DS; Department of Clinical Pharmacy, Clinical Pharmacology and Toxicology, Zuyderland Medical Centre, Sittard-Geleen/Heerlen, Netherlands., Winkens B; Department of methodology and statistics, CAPHRI Care and Public Health Research Institute, Maastricht University Medical Center, Maastricht, Netherlands., van Moorsel SAW; Department of Pharmacy, Jeroen Bosch Hospital, 's-Hertogenbosch, Netherlands.; Department of Clinical Pharmacy, Bernhoven Hospital, Uden, Netherlands., van Oijen BPC; Department of Clinical Pharmacy, Clinical Pharmacology and Toxicology, Zuyderland Medical Centre, Sittard-Geleen/Heerlen, Netherlands., Bus P; Department of Gastroenterology and Hepatology, Laurentius Hospital, Roermond, Netherlands., Pierik MJ; Department of Gastroenterology and Hepatology, Maastricht University Medical Center, Maastricht, Netherlands., Simsek M; Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam, Netherlands., de Boer NKH; Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam, Netherlands., Leers MPG; Department of Clinical Chemistry and Hematology, Zuyderland Medical Centre, Sittard-Geleen/Heerlen, Netherlands.; Faculty of Science, Open Universiteit, Heerlen, Netherlands., Wong DR; Department of Clinical Pharmacy, Clinical Pharmacology and Toxicology, Zuyderland Medical Centre, Sittard-Geleen/Heerlen, Netherlands., van Bodegraven AA; Department of Gastroenterology and Hepatology, Maastricht University Medical Center, Maastricht, Netherlands.; Department of Gastroenterology, Geriatrics, Internal and Intensive Care Medicine (Co-MIK), Zuyderland Medical Centre, Sittard-Geleen/Heerlen, Netherlands.
Publikováno v: British journal of clinical pharmacology [Br J Clin Pharmacol] 2024 Dec; Vol. 90 (12), pp. 3296-3307. Date of Electronic Publication: 2024 Aug 25.
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6
Editorial & Opinion
Comment on: A Soaring Price, a Silent Fight: Thioguanine Portends New Access Barriers to Life-Saving Treatments for Children With Cancer: The Ugly Duck or The Chicken with the Golden Eggs: The Crisis in Thioguanine Accessibility.
Autor: Bayoumy AB; Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam, The Netherlands., Mulder CJJ; Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam, The Netherlands., De Boer NKH; Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam, The Netherlands., Derijks LJJ; Department of Clinical Pharmacy and Clinical Pharmacology, Máxima Medical Center, Veldhoven, The Netherlands.; Department of Clinical Pharmacy and Toxicology, Maastricht University Medical Center, Maastricht, The Netherlands., Yang JJ; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Schmiegelow K; Department of Pediatrics and Adolescent Medicine, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Publikováno v: Pediatric blood & cancer [Pediatr Blood Cancer] 2024 Nov 30, pp. e31464. Date of Electronic Publication: 2024 Nov 30.
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7
Editorial & Opinion
DNA-Thioguanine (DNA-TG) Is a Promising Novel Method to Predict Adverse Events to Thiopurine in Inflammatory Bowel Disease.
Autor: Bayoumy AB; Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam, The Netherlands., Derijks LJJ; Department of Clinical Pharmacy and Clinical Pharmacology, Máxima Medical Center, Veldhoven, The Netherlands.; Department of Clinical Pharmacy and Toxicology, Maastricht University Medical Center, Maastricht, The Netherlands., de Boer NKH; Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam, The Netherlands.
Publikováno v: Inflammatory bowel diseases [Inflamm Bowel Dis] 2024 Oct 24. Date of Electronic Publication: 2024 Oct 24.
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8
Akademický článek
Next-generation IgA-SEQ allows for high-throughput, anaerobic, and metagenomic assessment of IgA-coated bacteria.
Autor: van Gogh M; Medical Microbiology Department, UMC Utrecht, Utrecht, The Netherlands., Louwers JM; Department of Gastroenterology and Hepatology, UMC Utrecht, Utrecht, The Netherlands., Celli A; Medical Microbiology Department, UMC Utrecht, Utrecht, The Netherlands., Gräve S; Medical Microbiology Department, UMC Utrecht, Utrecht, The Netherlands., Viveen MC; Medical Microbiology Department, UMC Utrecht, Utrecht, The Netherlands., Bosch S; Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., de Boer NKH; Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Verheijden RJ; Department of Medical Oncology, UMC Utrecht, Utrecht University, Utrecht, The Netherlands., Suijkerbuijk KPM; Department of Medical Oncology, UMC Utrecht, Utrecht University, Utrecht, The Netherlands., Brand EC; Department of Gastroenterology and Hepatology, UMC Utrecht, Utrecht, The Netherlands., Top J; Medical Microbiology Department, UMC Utrecht, Utrecht, The Netherlands., Oldenburg B; Department of Gastroenterology and Hepatology, UMC Utrecht, Utrecht, The Netherlands., de Zoete MR; Medical Microbiology Department, UMC Utrecht, Utrecht, The Netherlands. M.R.deZoete-2@umcutrecht.nl.
Publikováno v: Microbiome [Microbiome] 2024 Oct 21; Vol. 12 (1), pp. 211. Date of Electronic Publication: 2024 Oct 21.
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9
Akademický článek
Interobserver agreement of current and new proposed endoscopic scores for postoperative recurrence in Crohn's disease.
Autor: Bak MTJ; Department of Gastroenterology and Hepatology (1), Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands., Hammoudi N; Gastroenterology Department, Hôpital Saint-Louis-APHP, Université Paris Cité, INSERM U1160, Paris, France., Allez M; Gastroenterology Department, Hôpital Saint-Louis-APHP, Université Paris Cité, INSERM U1160, Paris, France., Silverberg MS; Division of Gastroenterology, Department of Medicine, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada., Schellekens IM; Department of Gastroenterology and Hepatology (1), Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands., Erler NS; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands; Department of Biostatistics, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Dijkstra G; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Romberg-Camps M; Department of Gastroenterology, Geriatrics, Internal and Intensive Care Medicine (Co-MIK), Zuyderland Medical Centre, Heerlen-Sittard-Geleen, the Netherlands., de Boer NKH; Department of Gastroenterology and Hepatology, AGEM Research Institute, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., Jansen SV; Department of Gastroenterology and Hepatology, Reinier de Graaf Groep, Delft, the Netherlands., van der Marel S; Department of Gastroenterology and Hepatology, Haaglanden Medical Center, The Hague, the Netherlands., Horjus CS; Department of Gastroenterology and Hepatology, Rijnstate Hospital, Arnhem, the Netherlands., Visschedijk MC; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Goetgebuer RL; Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam, the Netherlands., van Dop WA; Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, the Netherlands., Hoekstra J; Department of Gastroenterology and Hepatology, Amphia Hospital, Breda, the Netherlands., Bodelier AGL; Department of Gastroenterology and Hepatology, Amphia Hospital, Breda, the Netherlands., Molendijk I; Department of Gastroenterology and Hepatology (1), Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands., Derikx LAAP; Department of Gastroenterology and Hepatology (1), Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands., van Schaik FDM; Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, the Netherlands., West RL; Department of Gastroenterology and Hepatology, Franciscus Gasthuis & Vlietland, Rotterdam, the Netherlands., Duijvestein M; Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, the Netherlands., Janneke van der Woude C; Department of Gastroenterology and Hepatology (1), Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands., van Ruler O; Department of Surgery, IJsselland Hospital, Capelle aan den IJssel, the Netherlands; Department of Surgery, Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands., de Vries AC; Department of Gastroenterology and Hepatology (1), Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands. Electronic address: a.c.devries@erasmusmc.nl.
Publikováno v: Gastrointestinal endoscopy [Gastrointest Endosc] 2024 Oct; Vol. 100 (4), pp. 703-709.e4. Date of Electronic Publication: 2024 Mar 08.
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10
Akademický článek
Faecal Volatile Organic Compounds to Detect Colorectal Neoplasia in Lynch Syndrome-A Prospective Longitudinal Multicentre Study.
Autor: van Liere ELSA; Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam, The Netherlands., Ramsoekh D; Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam, The Netherlands., Daulton E; School of Engineering, University of Warwick, Coventry, UK., Dakkak M; Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam, The Netherlands.; School of Medicine, Vrije Universiteit, Amsterdam, The Netherlands., van Lingen JM; Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam, The Netherlands.; School of Medicine, Vrije Universiteit, Amsterdam, The Netherlands., Stewart TK; School of Engineering, University of Warwick, Coventry, UK., Bosch S; Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam, The Netherlands., Carvalho B; Department of Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands., Dekker E; Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam, The Netherlands., Jacobs MAJM; Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam, The Netherlands., Koornstra JJ; Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Kuijvenhoven JP; Department of Gastroenterology and Hepatology, Spaarne Gasthuis, Hoofddorp, The Netherlands., van Leerdam ME; Department of Gastrointestinal Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands., de Meij TGJ; Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam, The Netherlands.; Department of Paediatric Gastroenterology, Amsterdam University Medical Center, Amsterdam, The Netherlands., Meijer GA; Department of Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands., Spaander MCW; Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands., Covington JA; School of Engineering, University of Warwick, Coventry, UK., de Boer NKH; Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam, The Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam, The Netherlands.
Publikováno v: Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2025 Jan; Vol. 61 (1), pp. 145-158. Date of Electronic Publication: 2024 Oct 18.
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