Evaluating pediatric tuberculosis dosing guidelines: A model-based individual data pooled analysis.

Autor: Galileya LT; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.; Training and Research Unit of Excellence, Kamuzu University of Health Sciences, Blantyre, Malawi., Wasmann RE; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa., Chabala C; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.; Department of Pediatrics, University of Zambia, School of Medicine, Lusaka, Zambia.; University Teaching Hospitals-Children's Hospital, Lusaka, Zambia., Rabie H; Department of Pediatrics and Child Health and Family Center for Research with Ubuntu, Stellenbosch University, Cape Town, South Africa., Lee J; Drugs for Neglected Diseases initiative, Geneva, Switzerland., Njahira Mukui I; Drugs for Neglected Diseases initiative, Geneva, Switzerland., Hesseling A; Desmond Tutu TB Centre, Department of Pediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., Zar H; Department of Pediatrics and Child Health, Red Cross War Memorial Children's Hospital, and SA-MRC Unit on Child & Adolescent Health, University of Cape Town, Cape Town, South Africa., Aarnoutse R; Radboud University Medical Center, Nijmegen, the Netherlands., Turkova A; Medical Research Council Clinical Trials Unit at University College London, Institute of Clinical Trials and Methodology, London, United Kingdom., Gibb D; Medical Research Council Clinical Trials Unit at University College London, Institute of Clinical Trials and Methodology, London, United Kingdom., Cotton MF; Department of Pediatrics and Child Health and Family Center for Research with Ubuntu, Stellenbosch University, Cape Town, South Africa., McIlleron H; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.; Wellcome Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa., Denti P; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

Publikováno v: PLoS medicine [PLoS Med] 2023 Nov 21; Vol. 20 (11), pp. e1004303. Date of Electronic Publication: 2023 Nov 21 (Print Publication: 2023).