Products of the polymerase-encoding region of the coronavirus IBV

Autor: Brierley I, Mike Boursnell, Mm, Binns, Bilimoria B, Nj, Rolley, Td, Brown, Sc, Inglis

Publikováno v: Europe PubMed Central

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2d648e43a57647bc529672adc70c221d
https://pubmed.ncbi.nlm.nih.gov/1966413

Isavuconazole and voriconazole inhibition of sterol 14α-demethylases (CYP51) from Aspergillus fumigatus and Homo sapiens.

Autor: Warrilow AGS; Centre for Cytochrome P450 Biodiversity, Institute of Life Science, Swansea University Medical School, Swansea SA2 8PP, UK., Parker JE; Centre for Cytochrome P450 Biodiversity, Institute of Life Science, Swansea University Medical School, Swansea SA2 8PP, UK., Price CL; Centre for Cytochrome P450 Biodiversity, Institute of Life Science, Swansea University Medical School, Swansea SA2 8PP, UK., Rolley NJ; Centre for Cytochrome P450 Biodiversity, Institute of Life Science, Swansea University Medical School, Swansea SA2 8PP, UK., Nes WD; Center for Chemical Biology, Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas, USA., Kelly DE; Centre for Cytochrome P450 Biodiversity, Institute of Life Science, Swansea University Medical School, Swansea SA2 8PP, UK., Kelly SL; Centre for Cytochrome P450 Biodiversity, Institute of Life Science, Swansea University Medical School, Swansea SA2 8PP, UK. Electronic address: s.l.kelly@swansea.ac.uk.

Publikováno v: International journal of antimicrobial agents [Int J Antimicrob Agents] 2019 Oct; Vol. 54 (4), pp. 449-455. Date of Electronic Publication: 2019 Jul 13.

Azole Antifungal Sensitivity of Sterol 14α-Demethylase (CYP51) and CYP5218 from Malassezia globosa.

Autor: Warrilow AG; Centre for Cytochrome P450 Biodiversity, Institute of Life Science, Swansea University Medical School, Swansea, Wales SA2 8PP, United Kingdom., Price CL; Centre for Cytochrome P450 Biodiversity, Institute of Life Science, Swansea University Medical School, Swansea, Wales SA2 8PP, United Kingdom., Parker JE; Centre for Cytochrome P450 Biodiversity, Institute of Life Science, Swansea University Medical School, Swansea, Wales SA2 8PP, United Kingdom., Rolley NJ; Centre for Cytochrome P450 Biodiversity, Institute of Life Science, Swansea University Medical School, Swansea, Wales SA2 8PP, United Kingdom., Smyrniotis CJ; Chemistry and Biochemistry Department, University of California, Santa Cruz, CA 95064 USA., Hughes DD; Plant Chemistry Group, School of Chemistry, Bangor University, Bangor, Gwynedd, Wales, LL57 2UW, United Kingdom., Thoss V; Plant Chemistry Group, School of Chemistry, Bangor University, Bangor, Gwynedd, Wales, LL57 2UW, United Kingdom., Nes WD; Center for Chemical Biology, Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409-1061., Kelly DE; Centre for Cytochrome P450 Biodiversity, Institute of Life Science, Swansea University Medical School, Swansea, Wales SA2 8PP, United Kingdom., Holman TR; Chemistry and Biochemistry Department, University of California, Santa Cruz, CA 95064 USA., Kelly SL; Centre for Cytochrome P450 Biodiversity, Institute of Life Science, Swansea University Medical School, Swansea, Wales SA2 8PP, United Kingdom.

Publikováno v: Scientific reports [Sci Rep] 2016 Jun 13; Vol. 6, pp. 27690. Date of Electronic Publication: 2016 Jun 13.

Clotrimazole as a potent agent for treating the oomycete fish pathogen Saprolegnia parasitica through inhibition of sterol 14α-demethylase (CYP51).

Autor: Warrilow AG; Centre for Cytochrome P450 Biodiversity, Institute of Life Science, College of Medicine, Swansea University, Swansea, Wales, United Kingdom., Hull CM; Centre for Cytochrome P450 Biodiversity, Institute of Life Science, College of Medicine, Swansea University, Swansea, Wales, United Kingdom., Rolley NJ; Centre for Cytochrome P450 Biodiversity, Institute of Life Science, College of Medicine, Swansea University, Swansea, Wales, United Kingdom., Parker JE; Centre for Cytochrome P450 Biodiversity, Institute of Life Science, College of Medicine, Swansea University, Swansea, Wales, United Kingdom., Nes WD; Center for Chemical Biology, Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas, USA., Smith SN; Centre for Cytochrome P450 Biodiversity, Institute of Life Science, College of Medicine, Swansea University, Swansea, Wales, United Kingdom., Kelly DE; Centre for Cytochrome P450 Biodiversity, Institute of Life Science, College of Medicine, Swansea University, Swansea, Wales, United Kingdom d.kelly@swansea.ac.uk s.l.kelly@swansea.ac.uk., Kelly SL; Centre for Cytochrome P450 Biodiversity, Institute of Life Science, College of Medicine, Swansea University, Swansea, Wales, United Kingdom d.kelly@swansea.ac.uk s.l.kelly@swansea.ac.uk.

Publikováno v: Applied and environmental microbiology [Appl Environ Microbiol] 2014 Oct; Vol. 80 (19), pp. 6154-66. Date of Electronic Publication: 2014 Aug 01.

Complementation of a Saccharomyces cerevisiae ERG11/CYP51 (sterol 14α-demethylase) doxycycline-regulated mutant and screening of the azole sensitivity of Aspergillus fumigatus isoenzymes CYP51A and CYP51B.

Autor: Martel CM; Institute of Life Science and School of Medicine, Swansea University, Swansea, Wales, United Kingdom., Parker JE, Warrilow AG, Rolley NJ, Kelly SL, Kelly DE

Publikováno v: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2010 Nov; Vol. 54 (11), pp. 4920-3. Date of Electronic Publication: 2010 Aug 23.