Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Nizar Bhalis"'
Myeloma immunoglobulin rearrangement and translocation detection through targeted capture sequencing
Autor:
Signy Chow, Olena Kis, David T Mulder, Arnavaz Danesh, Jeff Bruce, Ting Ting Wang, Donna Reece, Nizar Bhalis, Paola Neri, Peter JB Sabatini, Jonathan Keats, Suzanne Trudel, Trevor J Pugh
Publikováno v:
Life Science Alliance. 6:e202201543
Multiple myeloma is a plasma cell neoplasm characterized by clonal immunoglobulin V(D)J signatures and oncogenic immunoglobulin gene translocations. Additional subclonal genomic changes are acquired with myeloma progression and therapeutic selection.