Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Niyi S. Adelakun"'
Publikováno v:
Annals of Science and Technology. 6:28-46
Markhamia tomentosa crude extract and fractions exhibited potent growth inhibitory effects capable to induce apoptosis in cervical (HeLa) cancer cell line via in vitro model. Presently, interaction of M. tomentosa phytoconstituents with molecular dru
Autor:
Babatomiwa Kikiowo, Niyi S. Adelakun, Adewale J Ogunleye, Taiwo T. Ijatuyi, Wasiu O Alashe, Opeyemi Iwaloye
Publikováno v:
Recent Patents on Anti-Cancer Drug Discovery. 16:273-284
Background: Breast Cancer (BC), a common fatal disease and the deadliest cancer next to lung cancer, is characterized by an abnormal growth of cells in the tissues of the breast. BC chemotherapy is marked by targeting the activities of some receptors
Autor:
Ikponwmosa Obaseki, Oluwaseun Fapohunda, Niyi S. Adelakun, Eseiwi Obaseki, Olaposi I Omotuyi, Ayobami Adeniyi
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 40:3060-3070
Ubiquitin-specific protease 14 (USP14) is a member of the deubiquitinating enzymes (DUBs) involved in disrupting the ubiquitin-proteasome regulation system, responsible for the degradation of impaired and misfolded proteins, which is an essential mec
Autor:
Eunice Iyanuoluwa Oribamise, Olaposi I Omotuyi, Niyi S. Adelakun, Ojochenemi A Enejoh, Oyekanmi Nash
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 7, Iss, Pp 1421-1427 (2020)
Toxicology Reports, Vol 7, Iss, Pp 1421-1427 (2020)
Graphical abstract
Highlights • Exposure of Wistar rats to Streptozotocin (STZ) causes acute kidney injury and loss of nephron functions. • STZ-induced kidney injury is caused by ROS generation and pro-inflammatory cytokines. • CoF complet
Highlights • Exposure of Wistar rats to Streptozotocin (STZ) causes acute kidney injury and loss of nephron functions. • STZ-induced kidney injury is caused by ROS generation and pro-inflammatory cytokines. • CoF complet
Autor:
Babatomiwa Kikiowo, Damilohun Samuel Metibemu, Oluwatoyin Olajide Oludoyi, Adewale J Ogunleye, Olaposi I Omotuyi, Taiwo T. Ijatuyi, Olumide K Inyang, Temitope Israel David, Niyi S. Adelakun
Publikováno v:
BioImpacts, Vol 10, Iss 4, Pp 227-234 (2020)
BioImpacts : BI
BioImpacts : BI
Introduction: Gout is a type of painful inflammation initiated by the interactions between monosodium urate crystals and connective tissue. Xanthine oxidase (XO) catalyzes the oxidation of hypoxanthine to xanthine, then to uric acid. The primary trea
Autor:
Ayodeji A. Ojo, Olaposi I Omotuyi, Niyi S. Adelakun, Tomisin Happy Ogunwa, David Safronetz, Oyekanmi Nash
Publikováno v:
Chemical Biology & Drug Design. 93:544-555
Lassa virus infection is clinically characterized by multiorgan failure in humans. Without an FDA-approved vaccine, ribavirin is the frontline drug for the treatment but with attendant toxicities. 6-Fluoro-3-hydroxy-2-pyrazinecarboxamide (T-705) is a
Autor:
Oluwafemi.E Ekun, Damilohun Samuel Metibemu, Raymond.T Owolabi, Bamidele Adewumi, Gabriel O Eniafe, Eunice Iyanuoluwa Oribamise, Olaposi I Omotuyi, Niyi S. Adelakun, Olumide K Inyang, Temitope Israel David, Ojochenemi A Enejoh
Publikováno v:
Bioinformation
Available antimalarial drugs have been associated with numerous side effects, which include skin rashes and myelo-suppression. Therefore, it is of interest to explore compounds from natural source having drug-like properties without side effect. This
Autor:
Blessing Chinweotito Ogboo, Omobolanle Abimbola Abiodun, Ravindran Jaganathan, Emmanuel Ifeanyi Attah, Lawrence Edemhanria, Niyi S. Adelakun, Ankita Kumari, Suritra Bandyopadhyay, A.T. Kola-Mustapha
Background: Medicinal plants, as rich sources of bioactive compounds with antiviral properties, are now being explored for the development of drugs against SARS-CoV-2.Aims: Identification of promising compounds for the treatment of COVID-19 from natu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a583c111fa074bfc56e9099cbf5e2dd
Autor:
Olaposi I Omotuyi, Damilohun Samuel Metibemu, Raphael Taiwo Aruleba, Abidemi Paul Kappo, Babatunji Emmanuel Oyinloye, Ramona Hurdayal, Oyekanmi Nash, Niyi S. Adelakun, Basiru Olaitan Ajiboye
The transnational spread of coronavirus (2019-nCoV) first detected in Wuhan is causing global panic; thus, accelerated research into clinical intervention is of high necessity. The spike glycoprotein structure has been resolved, and its affinity to h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::619090feadc6b0c65bf333c9cad29a66
https://doi.org/10.20944/preprints202003.0125.v1
https://doi.org/10.20944/preprints202003.0125.v1
Autor:
Adewale J Ogunleye, Olaposi I Omotuyi, Oluwatoba Emmanuel Oyeneyin, Gabriel O Eniafe, Yakubu O Adeniran, Joseph O Osunmuyiwa, Ojochenemi A Enejoh, Niyi S. Adelakun, Olumide K Inyang, Sidiqat A. Shodehinde, Damilohun Samuel Metibemu, Bamidele Adewumi
Publikováno v:
Bioinformation
Asthma is an inflammatory disease of the airway that poses a major threat to human health. With increase industrialization in the developed and developing countries, the incidence of asthma is on the rise. The β2-adrenergic receptor is an important