Zobrazeno 1 - 10 of 287 pro vyhledávání: '"Nixey T"'
1
Tryptanthrin Analogs Substoichiometrically Inhibit Seeded and Unseeded Tau4RD Aggregation.
Autor: James EI; Department of Medicinal Chemistry, University of Washington, Seattle, WA.; Molecular Engineering & Sciences Institute, University of Washington, Seattle, WA., Baggett DW; Department of Medicinal Chemistry, University of Washington, Seattle, WA.; Current address: Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN., Chang E; Takeda Development Center Americas, San Diego, CA., Schachter J; Takeda Development Center Americas, San Diego, CA., Nixey T; Takeda Development Center Americas, San Diego, CA., Choi K; Takeda Development Center Americas, San Diego, CA., Guttman M; Department of Medicinal Chemistry, University of Washington, Seattle, WA.; Molecular Engineering & Sciences Institute, University of Washington, Seattle, WA., Nath A; Department of Medicinal Chemistry, University of Washington, Seattle, WA.; Molecular Engineering & Sciences Institute, University of Washington, Seattle, WA.
Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Feb 03. Date of Electronic Publication: 2024 Feb 03.
Zobrazit plný text záznamu
2
Akademický článek
Structure-guided Discovery of Dual-recognition Chemibodies.
Autor: Cheng AC; Department of Therapeutic Discovery, Amgen Discovery Research, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, CA, 94080, USA., Doherty EM; Department of Therapeutic Discovery, Amgen Discovery Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA, 91320, USA., Johnstone S; Department of Therapeutic Discovery, Amgen Discovery Research, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, CA, 94080, USA., DiMauro EF; Department of Therapeutic Discovery, Amgen Discovery Research, Amgen Inc., 360 Binney Street, Cambridge, MA, 02142, USA., Dao J; Department of Therapeutic Discovery, Amgen Discovery Research, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, CA, 94080, USA., Luthra A; Department of Therapeutic Discovery, Amgen Discovery Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA, 91320, USA., Ye J; Department of Therapeutic Discovery, Amgen Discovery Research, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, CA, 94080, USA., Tang J; Department of Therapeutic Discovery, Amgen Discovery Research, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, CA, 94080, USA., Nixey T; Department of Therapeutic Discovery, Amgen Discovery Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA, 91320, USA., Min X; Department of Therapeutic Discovery, Amgen Discovery Research, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, CA, 94080, USA., Tagari P; Department of Therapeutic Discovery, Amgen Discovery Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA, 91320, USA., Miranda LP; Department of Therapeutic Discovery, Amgen Discovery Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA, 91320, USA. lesm@amgen.com., Wang Z; Department of Therapeutic Discovery, Amgen Discovery Research, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, CA, 94080, USA. zwang@amgen.com.
Publikováno v: Scientific reports [Sci Rep] 2018 May 15; Vol. 8 (1), pp. 7570. Date of Electronic Publication: 2018 May 15.
Zobrazit plný text záznamu
4
Akademický článek
Assessment of structural and activity-related contributions of various PIM-1 kinase inhibitors in the treatment of leukemia and prostate cancer.
Autor: Sharma A; Department of Pharmaceutical Chemistry, ISF College of Pharmacy, Moga, Punjab, India., Dubey R; Department of Pharmaceutical Chemistry, ISF College of Pharmacy, Moga, Punjab, India., Asati V; Department of Medical Oncology, Sri Aurobindo Medical College and PG Institute, Indore, MP, India., Baweja GS; Department of Pharmaceutical Chemistry, ISF College of Pharmacy, Moga, Punjab, India., Gupta S; Department of Pharmaceutical Chemistry, ISF College of Pharmacy, Moga, Punjab, India., Asati V; Department of Pharmaceutical Chemistry, ISF College of Pharmacy, Moga, Punjab, India. vivekasatipharma47@gmail.com.
Publikováno v: Molecular diversity [Mol Divers] 2024 Apr 20. Date of Electronic Publication: 2024 Apr 20.
Zobrazit plný text záznamu
5
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
6
Kniha
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
7
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
8
Akademický článek
Discovery of 5-(1H-indol-5-yl)-1,3,4-thiadiazol-2-amines as potent PIM inhibitors.
Autor: Wu B; Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA. Electronic address: binw@amgen.com., Wang HL; Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Cee VJ; Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Lanman BA; Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Nixey T; Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Pettus L; Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Reed AB; Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Wurz RP; Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Guerrero N; Department of Oncology, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Sastri C; Department of Oncology, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Winston J; Department of Oncology, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Lipford JR; Department of Oncology, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Lee MR; Department of Molecular Structure and Characterization, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Mohr C; Department of Molecular Structure and Characterization, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Andrews KL; Department of Molecular Structure and Characterization, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Tasker AS; Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA.
Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2015 Feb 15; Vol. 25 (4), pp. 775-80. Date of Electronic Publication: 2015 Jan 07.
Zobrazit plný text záznamu
9
Akademický článek
The discovery and optimization of aminooxadiazoles as potent Pim kinase inhibitors.
Autor: Wurz RP; Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA. Electronic address: rwurz@amgen.com., Pettus LH; Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Jackson C; Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Wu B; Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Wang HL; Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Herberich B; Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Cee V; Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Lanman BA; Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Reed AB; Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Chavez F Jr; Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Nixey T; Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Laszlo J 3rd; Department of Discovery Technologies, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Wang P; Department of Molecular Structure and Characterization, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Nguyen Y; Department of Molecular Structure and Characterization, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Sastri C; Department of Oncology, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Guerrero N; Department of Oncology, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Winston J; Department of Oncology, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Lipford JR; Department of Oncology, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Lee MR; Department of Molecular Structure and Characterization, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Andrews KL; Department of Molecular Structure and Characterization, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Mohr C; Department of Molecular Structure and Characterization, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Xu Y; Department of Pharmacokinetics and Drug Metabolism, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Zhou Y; Department of Pharmacokinetics and Drug Metabolism, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Reid DL; Department of Pharmaceutics R&D, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA., Tasker AS; Department of Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799, USA.
Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2015 Feb 15; Vol. 25 (4), pp. 847-55. Date of Electronic Publication: 2015 Jan 07.
Zobrazit plný text záznamu
10
Akademický článek
Rh(II)‐Catalyzed Denitrogenative Reaction of N‐Sulfonyl‐1,2,3‐triazoles with Quinolones and Isoquinolones.
Autor: Pandey, Shivam1 (AUTHOR), Parveen, Sabiha1 (AUTHOR), Volla, Chandra M. R.1 (AUTHOR) Chandra.volla@chem.iitb.ac.in
Publikováno v: Chemistry - An Asian Journal. 10/17/2023, Vol. 18 Issue 20, p1-5. 5p.
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje