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Publikováno v:
In Drug Discovery Today April 2018 23(4):815-829
Akademický článek
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Autor:
Lynette C. Foo, Deepak Choudhury, Fang Yu, Sum Huan Ng, Walter Hunziker, Nivasini D, O Selva Kumar
Publikováno v:
Biotechnology and bioengineeringREFERENCES. 117(4)
Disruption of the blood-brain barrier (BBB) leads to various neurovascular diseases. Development of therapeutics required to cross the BBB is difficult due to a lack of relevant in vitro models. We have developed a three-dimensional (3D) microfluidic
Publikováno v:
Drug discovery today. 23(4)
Microfluidic platforms have recently become popular as in vitro models because of their superiority in recapitulating microenvironments compared with conventional in vitro models. By providing various biochemical and biomechanical cues, healthy and d