Centering and symmetry breaking in confined contracting actomyosin networks

Autor: Niv Ierushalmi, Maya Malik-Garbi, Angelika Manhart, Enas Abu Shah, Bruce L Goode, Alex Mogilner, Kinneret Keren

Publikováno v: eLife, Vol 9 (2020)

Centering and decentering of cellular components is essential for internal organization of cells and their ability to perform basic cellular functions such as division and motility. How cells achieve proper localization of their organelles is still n

Externí odkaz: https://doaj.org/article/fe062294b29646aa939cb012c89993c5

Size-dependent transition from steady contraction to waves in actomyosin networks with turnover

Autor: Ashwini Krishna, Mariya Savinov, Niv Ierushalmi, Alex Mogilner, Kinneret Keren

Actomyosin networks play essential roles in many cellular processes including intracellular transport, cell division, and cell motility, exhibiting a myriad of spatiotemporal patterns. Despite extensive research, how the interplay between network mec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99d529931bab0b6fb0860a40e729a0d1
https://doi.org/10.1101/2022.07.13.499885

Centering and symmetry breaking in confined contracting actomyosin networks

Autor: Angelika Manhart, Maya Malik-Garbi, Bruce L. Goode, Alex Mogilner, Niv Ierushalmi, Kinneret Keren, Enas Abu Shah

Publikováno v: eLife, Vol 9 (2020)
eLife

Centering and decentering of cellular components is essential for internal organization of cells and their ability to perform basic cellular functions such as division and motility. How cells achieve proper localization of their organelles is still n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2068ad74117b3e3866817b61399aadb2
https://elifesciences.org/articles/55368

Cellular Organization: Bulk Actin Network Flows Drive Ooplasm Segregation

Autor: Kinneret Keren, Niv Ierushalmi

Publikováno v: Current biology : CB. 29(15)

Actin networks in the bulk cytoplasm, rather than cortical dynamics, drive ooplasm segregation in zebrafish oocytes. A contracting actin network drags the ooplasm toward the animal pole, while 'comet tails' push the yolk granules in the opposite dire

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4040fca59173d9178dc85dea66d626
https://pubmed.ncbi.nlm.nih.gov/31080065

Roadmap on multiscale coupling of biochemical and mechanical signals during development

Autor: Ed Munro, Kasumi Kishi, Sham Tlili, Jean-Léon Maître, Stefano Di Talia, Yonit Maroudas-Sacks, Aryeh Warmflash, Paolo Caldarelli, Anna Kicheva, Zev J. Gartner, Timothy E. Saunders, Idse Heemskerk, Antoine Fruleux, Alan R. Rodrigues, Benjamin Stormo Stormo, Bassma Khamaisi, Amy Gladfelter Gladfelter, Edouard Hannezo, Jerome Gros, Pierre-François Lenne, David Sprinzak, Arezki Boudaoud, Laura Bocanegra-Moreno, Yuchen Long, Arthur Michaut, Amy E. Shyer, Kinneret Keren, Nicolas Minc

Publikováno v: Physical Biology
Physical Biology, 2021, ⟨10.1088/1478-3975/abd0db⟩
Physical biology
Physical Biology, Institute of Physics: Hybrid Open Access, 2021, ⟨10.1088/1478-3975/abd0db⟩

The way in which interactions between mechanics and biochemistry lead to the emergence of complex cell and tissue organization is an old question that has recently attracted renewed interest from biologists, physicists, mathematicians and computer sc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61445aebdb0942039b3bc247d7e31c77
https://hal.science/hal-03046260/file/Lenne+et+al_2020.pdf