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Discovery of Novel 5,6-Dihydro‑4H‑pyrido[2,3,4-de]quinazoline Irreversible Inhibitors Targeting Both Wild-Type and A775_G776insYVMA Mutated HER2 Kinases.

Autor: Yang, Leifu, Li, Yaxin, Du, Yunling, Guo, Yan, Guo, Zhenke, Liu, Baoxiu, Liu, Jianglin, Liu, Yanfei, Niu, Hongdan, Sun, Yueming, Yan, Henglin, Yang, Yajuan, Yu, Shannan, Zhang, Yifan, Zhang, Yuan, Zheng, Kun, Zheng, Nanqiao, Zhang, Xiaoqing, Zhang, Qiang, Hu, Liming

Publikováno v: Journal of Medicinal Chemistry; 4/11/2024, Vol. 67 Issue 7, p5662-5682, 21p

The effects of reduced dietary protein level on amino acid transporters and mTOR signaling pathway in pigs

Autor: Wang, Dan ^{a, b}, Wan, Xuebin ^{a, b}, Peng, Jian ^c, Xiong, Qi ^d, Niu, Hongdan ^{a, b}, Li, Huanan ^{a, b}, Chai, Jin ^{a, b, ∗∗}, Jiang, Siwen ^{a, b, ∗}

Publikováno v: In Biochemical and Biophysical Research Communications 1 April 2017 485(2):319-327

Discovery of Novel 5,6-Dihydro-4 H -pyrido[2,3,4- de ]quinazoline Irreversible Inhibitors Targeting Both Wild-Type and A775_G776insYVMA Mutated HER2 Kinases.

Autor: Yang L; College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China.; . Beijing Scitech MQ Pharmaceuticals Ltd., Beijing 101320, China., Li Y; College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China., Du Y; . Beijing Scitech MQ Pharmaceuticals Ltd., Beijing 101320, China., Guo Y; . Beijing Scitech MQ Pharmaceuticals Ltd., Beijing 101320, China., Guo Z; . Beijing Scitech MQ Pharmaceuticals Ltd., Beijing 101320, China., Liu B; . Beijing Scitech MQ Pharmaceuticals Ltd., Beijing 101320, China., Liu J; . Beijing Scitech MQ Pharmaceuticals Ltd., Beijing 101320, China., Liu Y; . Beijing Scitech MQ Pharmaceuticals Ltd., Beijing 101320, China., Niu H; . Beijing Scitech MQ Pharmaceuticals Ltd., Beijing 101320, China., Sun Y; . Beijing Scitech MQ Pharmaceuticals Ltd., Beijing 101320, China., Yan H; . Beijing Scitech MQ Pharmaceuticals Ltd., Beijing 101320, China., Yang Y; . Beijing Scitech MQ Pharmaceuticals Ltd., Beijing 101320, China., Yu S; . Beijing Scitech MQ Pharmaceuticals Ltd., Beijing 101320, China., Zhang Y; . Beijing Scitech MQ Pharmaceuticals Ltd., Beijing 101320, China., Zhang Y; . Beijing Scitech MQ Pharmaceuticals Ltd., Beijing 101320, China., Zheng K; . Beijing Scitech MQ Pharmaceuticals Ltd., Beijing 101320, China., Zheng N; . Beijing Scitech MQ Pharmaceuticals Ltd., Beijing 101320, China., Zhang X; . Beijing Scitech MQ Pharmaceuticals Ltd., Beijing 101320, China., Zhang Q; . Beijing Scitech MQ Pharmaceuticals Ltd., Beijing 101320, China., Hu L; College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China.; Beijing Key Laboratory of Environmental and Viral Oncology, Beijing 100124, China.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2024 Apr 11; Vol. 67 (7), pp. 5662-5682. Date of Electronic Publication: 2024 Mar 22.