Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Nitzan Gonen"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
Gonadal sex determination in mice is a complex and dynamic process, which is crucial for the development of functional reproductive organs. The expression of genes involved in this process is regulated by a variety of genetic and epigenetic mechanism
Externí odkaz:
https://doaj.org/article/e081160dedaf4d97a8edebbdb1e0b796
Publikováno v:
PLoS Genetics, Vol 13, Iss 2, p e1006584 (2017)
[This corrects the article DOI: 10.1371/journal.pgen.1006520.].
Externí odkaz:
https://doaj.org/article/9c040fca61a94a8bb793005e73fcaf5a
Publikováno v:
PLoS Genetics, Vol 13, Iss 1, p e1006520 (2017)
During mouse sex determination, transient expression of the Y-linked gene Sry up-regulates its direct target gene Sox9, via a 3.2 kb testis specific enhancer of Sox9 (TES), which includes a core 1.4 kb element, TESCO. SOX9 activity leads to different
Externí odkaz:
https://doaj.org/article/cc440842b5db4a9eb84a74836d354bcf
Autor:
Masomeh Askari, Svetlana A. Yatsenko, Robin Lovell-Badge, Tiphanie Merel-Chali, Balázs Gellén, Nitzan Gonen, Leila Fusee, Rana Mainpal, Mariana Costanzo, Inas Mazen, Anu Bashamboo, Anahita Mohseni Meybodi, Esperanza Berensztein, Joelle Bignon-Topalovic, Caroline Eozenou, Natalia Perez Garrido, Alicia Belgorosky, Andrea J. Berman, Roberta Migale, Ken McElreavey, Rita Bertalan, Alaa K. Kamel, Mona K. Mekkawy, Maria Sol Touzon, Priti Singh, Pablo Ramirez, Gabriela Guercio, Aleksandar Rajkovic, Mehdi Totonchi, Selma F. Witchel, Roxana Marino, John C. Schimenti, Anne Jørgensen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2020, 117 (24), pp.13680-13688. ⟨10.1073/pnas.1921676117⟩
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (24), pp.13680-13688. ⟨10.1073/pnas.1921676117⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2020, 117 (24), pp.13680-13688. ⟨10.1073/pnas.1921676117⟩
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (24), pp.13680-13688. ⟨10.1073/pnas.1921676117⟩
International audience; Sex determination in mammals is governed by antagonistic interactions of two genetic pathways, imbalance in which may lead to disorders/differences of sex development (DSD) in human. Among 46,XX individuals with testicular DSD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f28b185a9a5aeb46bd22dbfa6cc25dd
https://doi.org/10.1073/pnas.1921676117
https://doi.org/10.1073/pnas.1921676117
Autor:
Emmanuel Frachon, Andreia Bernardo, Richard Mitter, Almira Chervova, Inas Mazen, Ken McElreavey, Nitzan Gonen, Samy Gobaa, Robin Lovell-Badge, Pierre-Henri Commere, Caroline Eozenou, Anu Bashamboo
During embryonic development, mutually antagonistic signaling cascades determine the fate of the bipotential gonad towards a testicular or ovarian identity. Errors in this process result in human Disorders of Sex Development (DSDs), where there is di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c50293ed48c8b9d296def513af8c1634
https://doi.org/10.1101/2021.10.22.465384
https://doi.org/10.1101/2021.10.22.465384
Autor:
Nitzan Gonen, Francis Poulat
Publikováno v:
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation. 15(5-6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aaf935b2020c5462e38b378ed3a2012
https://pubmed.ncbi.nlm.nih.gov/34823254
https://pubmed.ncbi.nlm.nih.gov/34823254
Autor:
Roxana Marino, Leila Fusee, Caroline Eozenou, Gabriela Guercio, Masomeh Askari, Anne Jørgensen, Mohseni Meybodi A, Mehdi Totonchi, Selma F. Witchel, Maria Sol Touzon, Joelle Bignon-Topalovic, Merel-Chali T, Alaa K. Kamel, Mariana Costanzo, Priti Singh, Svetlana A. Yatsenko, Balázs Gellén, Pablo Ramirez, Roberta Migale, Nitzan Gonen, Andrea J. Berman, Rana Mainpal
Publikováno v:
Yearbook of Paediatric Endocrinology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f95486437d117be986928b9c5f185f8d
https://doi.org/10.1530/ey.18.6.2
https://doi.org/10.1530/ey.18.6.2
Autor:
Anu Bashamboo, Nitzan Gonen, Caroline Eozenou, Richard Mitter, Andreia Sofia Bernardo, Almira Chervova Chervova, Emmanuel Frachon, Pierre-Henri Commère, Sylvie Brailly-Tabard, Inas Mazen, Samy Gobaa, James Smith, Kenneth McElreavey, Robin Lovell-Badge
Publikováno v:
Journal of the Endocrine Society. 6:A705-A705
During embryonic development, mutually antagonistic signaling cascades determine the fate of the bipotential gonad towards a testicular or ovarian identity. Errors in this process result in human Disorders of Sex Development (DSDs), where there is di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7502b012321b197d2061de45a7546962
https://doi.org/10.1210/jendso/bvac150.1454
https://doi.org/10.1210/jendso/bvac150.1454
Publikováno v:
Sex Dev
Sex determination is the process by which an initial bipotential gonad adopts either a testicular or ovarian cell fate. The inability to properly complete this process leads to a group of developmental disorders classified as disorders of sex develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebb5bb3ab33b6ace40231ae50dedcd0
https://pubmed.ncbi.nlm.nih.gov/34710870
https://pubmed.ncbi.nlm.nih.gov/34710870
Publikováno v:
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation. 16(2-3)
SOX genesare master regulatory genes controlling development and are fundamental to the establishment of sex determination in a multitude of organisms. The discovery of the master sex-determining gene SRY in 1990 was pivotal for the understanding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2deb95f2a4694d1d237106cb1bb96f8b
https://pubmed.ncbi.nlm.nih.gov/35760052
https://pubmed.ncbi.nlm.nih.gov/35760052