Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Nityakalyani Srinivas"'
Autor:
Martina Werneburg, Pauline E. Misson, Leo Eberl, Steven J. Demarco, Daniel Obrecht, Kathrin Riedel, Frank Gombert, Jürg Zumbrunn, Jessica Steinmann, Ricardo Augusto Dias, Nityakalyani Srinivas, Peter Hunziker, Andres Käch, Bernhard J. Ueberbacher, Alexander Lederer, Katja Zerbe, Stefan Schauer, Francesca Bernardini, John A. Robinson, Urs Ziegler, Benjamin Van der Meijden, Heiko Henze, Peter Jetter
Publikováno v:
Science
Science; Vol 327
Science; Vol 327
Killing Pseudomonas Gram-negative Pseudomonas bacteria are opportunistic pathogens, and drug-resistant strains present a serious health problem. Srinivas et al. (p. 1010 ) synthesized a family of peptidomimetic antibiotics that is active only against
Publikováno v:
Organicbiomolecular chemistry. 5(19)
The turn-forming D-Pro-L-Pro template has been frequently used to promote regular beta-hairpin conformations in cyclic protein epitope mimetics. Here the use of three isomeric biaryl templates has been studied as alternatives to D-Pro-L-Pro in the pr