Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Nitya S, Ramadoss"'
Autor:
Jae-Seung Moon, Shady Younis, Nitya S. Ramadoss, Radhika Iyer, Khushboo Sheth, Orr Sharpe, Navin L. Rao, Stephane Becart, Julie A. Carman, Eddie A. James, Jane H. Buckner, Kevin D. Deane, V. Michael Holers, Susan M. Goodman, Laura T. Donlin, Mark M. Davis, William H. Robinson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
The immune mechanisms underlying synovitis and joint tissue destruction in rheumatoid arthritis (RA) remain incompletely defined. Here, the authors demonstrate that ACPA+ RA patients have activated clonally expanded cytotoxic GZMB+ CD8+ T cells in bl
Externí odkaz:
https://doaj.org/article/256fdecef1e149f1a62547c63372d7f7
Autor:
Katherine L Williams, Megan Stumpf, Nicole Elise Naiman, Shilei Ding, Meghan Garrett, Theodore Gobillot, Dani Vézina, Katharine Dusenbury, Nitya S Ramadoss, Ryan Basom, Peter S Kim, Andrés Finzi, Julie Overbaugh
Publikováno v:
PLoS Pathogens, Vol 15, Iss 2, p e1007572 (2019)
Antibodies that mediate killing of HIV-infected cells through antibody-dependent cellular cytotoxicity (ADCC) have been implicated in protection from HIV infection and disease progression. Despite these observations, these types of HIV antibodies are
Externí odkaz:
https://doaj.org/article/9202a8f8f96b4f278d624c2134b41cf6
Autor:
R. Camille Brewer, Tobias V. Lanz, Caryn R. Hale, Gregory D. Sepich-Poore, Cameron Martino, Austin D. Swafford, Thomas S. Carroll, Sarah Kongpachith, Lisa K. Blum, Serra E. Elliott, Nathalie E. Blachere, Salina Parveen, John Fak, Vicky Yao, Olga Troyanskaya, Mayu O. Frank, Michelle S. Bloom, Shaghayegh Jahanbani, Alejandro M. Gomez, Radhika Iyer, Nitya S. Ramadoss, Orr Sharpe, Sangeetha Chandrasekaran, Lindsay B. Kelmenson, Qian Wang, Heidi Wong, Holly L. Torres, Mark Wiesen, Dana T. Graves, Kevin D. Deane, V. Michael Holers, Rob Knight, Robert B. Darnell, William H. Robinson, Dana E. Orange
Publikováno v:
Science Translational Medicine. 15
Periodontal disease is more common in individuals with rheumatoid arthritis (RA) who have detectable anti-citrullinated protein antibodies (ACPAs), implicating oral mucosal inflammation in RA pathogenesis. Here, we performed paired analysis of human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe98296461d8cd7e49e173f6484eb349
https://doi.org/10.1126/scitranslmed.abq8476
https://doi.org/10.1126/scitranslmed.abq8476
Autor:
Jae-Seung Moon, Shady Younis, Nitya S. Ramadoss, Radhika Iyer, Khushboo Sheth, Orr Sharpe, Navin L. Rao, Stephane Becart, Julie A. Carman, Eddie A. James, Jane H. Buckner, Kevin D. Deane, V. Michael Holers, Susan M. Goodman, Laura T. Donlin, Mark M. Davis, William H. Robinson
The immune mechanisms that mediate synovitis and joint destruction in rheumatoid arthritis (RA) remain poorly defined. Although increased levels of CD8+T cells have been described in RA, their role in pathogenesis remains unclear. Here we perform sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57b50f886706e2785f80c79f11b44dab
https://doi.org/10.1101/2022.11.10.22282203
https://doi.org/10.1101/2022.11.10.22282203
Autor:
Shaghayegh, Jahanbani, Paige S, Hansen, Lisa K, Blum, Effie E, Bastounis, Nitya S, Ramadoss, Mallesh, Pandrala, Jessica Marie, Kirschmann, Grace Sisemore, Blacker, Zelda Z, Love, Irving L, Weissman, Fahimeh, Nemati, Michal Caspi, Tal, William H, Robinson
Publikováno v:
Clinical Immunology. 246:109180
Borrelia burgdorferi (Bb) infection causes Lyme disease, for which there is need for more effective therapies. Here, we sequenced the antibody repertoire of plasmablasts in Bb-infected humans. We expressed recombinant monoclonal antibodies (mAbs) rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0204a0507ece940bc600dd481b31796c
https://doi.org/10.1016/j.clim.2022.109180
https://doi.org/10.1016/j.clim.2022.109180
Autor:
Tobias V. Lanz, Lauren J. Lahey, Nitya S. Ramadoss, William H. Robinson, Shaghayegh Jahanbani, R. Camille Brewer
Publikováno v:
Nat Immunol
The first ever US Food and Drug Administration-approved messenger RNA vaccines are highly protective against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)1-3. However, the contribution of each dose to the generation of antibodies again
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160104fb1d1764a7678db35115bbb76f
https://europepmc.org/articles/PMC8776031/
https://europepmc.org/articles/PMC8776031/
Autor:
Peter A. Nigrovic, Jonathan E. Bennett, for Pedi Lyme Net, Lise E. Nigrovic, Nitya S. Ramadoss, Aris Garro, Michael N. Levas, William H. Robinson, Felix A Radtke
Publikováno v:
Journal of Clinical Microbiology. 59
Lyme disease is commonly diagnosed by serologic response to Borrelia burgdorferi and related species, but the relationship between serologic targets and clinical features is unknown. We developed a multiantigen Luminex-based panel and evaluated IgG r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4797b0f86c370d747cd64ae9a7fbfe40
https://doi.org/10.1128/jcm.01344-21
https://doi.org/10.1128/jcm.01344-21
The first ever messenger RNA (mRNA) vaccines received emergency approvals in December 2020 and are highly protective against SARS-CoV-21–3. However, the contribution of each dose to the generation of antibodies against SARS-CoV-2 spike (S) protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cdc1a1b48970c23b4178d0485080392
https://doi.org/10.1101/2021.07.20.21260822
https://doi.org/10.1101/2021.07.20.21260822
Autor:
Mark W. Eshoo, Avi Ma'ayan, William H. Robinson, Jinshui Fan, Michael R. Mosel, John Erol Evangelista, Matteo Danieletto, Allison Bailey, Megan L. Wojciechowicz, Nitya S. Ramadoss, Jason Bobe, Alison W. Rebman, Mark J. Soloski, John N. Aucott, Sherry L. Jenkins, Daniel J.B. Clarke
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Although widely prevalent, Lyme disease is still under-diagnosed and misunderstood. Here we followed 73 acute Lyme disease patients and uninfected controls over a period of a year. At each visit, RNA-sequencing was applied to profile patients' periph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::802bae6cb30dfef1468b4767a8f419d2
https://doi.org/10.3389/fimmu.2021.636289
https://doi.org/10.3389/fimmu.2021.636289
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57537 (2013)
Nonstop mRNAs pose a challenge for bacteria, because translation cannot terminate efficiently without a stop codon. The trans-translation pathway resolves nonstop translation complexes by removing the nonstop mRNA, the incomplete protein, and the sta
Externí odkaz:
https://doaj.org/article/2f35ceb8ca664aa4a7ad4b74067270d9