Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nitya M, Jacob"'
Autor:
Nitya M. Jacob, Mohit Sharma, Huong Le, Kevin A. T. Silverstein, Kathryn C. Johnson, George Karypis, Wei Shou Hu, Joann Mudge, Thiruvarangan Ramaraj, Hsu Yuan Fu, Nandita Vishwanathan, Getiria Onsongo, Arpan Bandyopadhyay
Publikováno v:
Biotechnology Journal. 11:1151-1157
Chinese hamster Ovary (CHO) cell lines are the dominant industrial workhorses for therapeutic recombinant protein production. The availability of genome sequence of Chinese hamster and CHO cells will spur further genome and RNA sequencing of producin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::782f757f7781d4bef7cd7b592a0b58fb
https://doi.org/10.1002/biot.201500455
https://doi.org/10.1002/biot.201500455
Publikováno v:
Biotechnology Letters. 37:1553-1564
At the core of a biomanufacturing process for recombinant proteins is the production cell line. It influences the productivity and product quality. Its characteristics also dictate process development, as the process is optimized to complement the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcad375cb258a6f71a776eb7fe41e6ee
https://doi.org/10.1007/s10529-015-1843-z
https://doi.org/10.1007/s10529-015-1843-z
Autor:
Nandita Vishwanathan, Nitya M. Jacob, Hsu Yuan Fu, Wei Shou Hu, Huong Le, Dong-Yup Lee, Andrew Yongky, Kathryn C. Johnson, Faraaz N.K. Yusufi
Publikováno v:
Biotechnology and Bioengineering. 112:965-976
Transcriptomics is increasingly being used on Chinese hamster ovary (CHO) cells to unveil physiological insights related to their performance during production processes. The rich transcriptome data can be exploited to provide impetus for systems inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f5a63df4c639a86bec88a1069be52f6
https://doi.org/10.1002/bit.25513
https://doi.org/10.1002/bit.25513
Autor:
Bernard Loo, Wei Shou Hu, Anne Kantardjieff, Nitya M. Jacob, Zhong Liu, Nandita Vishwanathan, Sze Wai Ng, Yung Shyeng Tsao, Huong Le
Publikováno v:
Biotechnology and Bioengineering. 111:518-528
Dihydrofolate reductase (DHFR) system is used to amplify the product gene to multiple copies in Chinese Hamster Ovary (CHO) cells for generating cell lines which produce the recombinant protein at high levels. The physiological changes accompanying t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6997111f71202ee8bddbb6720c94e2a
https://doi.org/10.1002/bit.25117
https://doi.org/10.1002/bit.25117
Autor:
Faraaz N.K. Yusufi, Miranda Yap, Wei Shou Hu, Peter Morin Nissom, Song Hui Chuah, Anne Kantardjieff, Nitya M. Jacob, Bhanu Chandra Mulukutla
Publikováno v:
Biotechnology Advances. 27:1028-1035
Chinese hamster ovary (CHO) cells are widely used in recombinant protein production, yet despite their importance in bioprocessing, few genomic resources have been developed for this cell line. Over the past several years, we have made considerable p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbff6aac5468b4641aba4c6c3a3de1c4
https://doi.org/10.1016/j.biotechadv.2009.05.023
https://doi.org/10.1016/j.biotechadv.2009.05.023
Publikováno v:
Biotechnology Progress. 25:1198-1215
The Second International Conference on Accelerating Biopharmaceutical Development was held in Coronado, California. The meeting was organized by the Society for Biological Engineering (SBE) and the American Institute of Chemical Engineers (AIChE); SB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145516ac36799050bb6a1b4aa5e89d07
https://doi.org/10.1002/btpr.263
https://doi.org/10.1002/btpr.263
Autor:
Nandita, Vishwanathan, Andrew, Yongky, Kathryn C, Johnson, Hsu-Yuan, Fu, Nitya M, Jacob, Huong, Le, Faraaz N K, Yusufi, Dong Yup, Lee, Wei-Shou, Hu
Publikováno v:
Biotechnology and bioengineering. 112(5)
Transcriptomics is increasingly being used on Chinese hamster ovary (CHO) cells to unveil physiological insights related to their performance during production processes. The rich transcriptome data can be exploited to provide impetus for systems inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::624579176ab7b7f1c49415553db2d2be
https://pubmed.ncbi.nlm.nih.gov/25450749
https://pubmed.ncbi.nlm.nih.gov/25450749
Autor:
Kathryn C. Johnson, Wei Shou Hu, Chetan T. Goudar, Nandita Vishwanathan, Andrew Yongky, Nitya M. Jacob, George Karypis, Karthik P. Jayapal
Publikováno v:
Biotechnology and bioengineering. 111(4)
Baby Hamster Kidney (BHK) cell lines are used in the production of veterinary vaccines and recombinant proteins. To facilitate transcriptome analysis of BHK cell lines, we embarked on an effort to sequence, assemble, and annotate transcript sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b25c4cfd1c2eddce48651cfb0b5d7d4
https://pubmed.ncbi.nlm.nih.gov/24249083
https://pubmed.ncbi.nlm.nih.gov/24249083
Autor:
Nandita, Vishwanathan, Huong, Le, Nitya M, Jacob, Yung-Shyeng, Tsao, Sze-Wai, Ng, Bernard, Loo, Zhong, Liu, Anne, Kantardjieff, Wei-Shou, Hu
Publikováno v:
Biotechnology and bioengineering. 111(3)
Dihydrofolate reductase (DHFR) system is used to amplify the product gene to multiple copies in Chinese Hamster Ovary (CHO) cells for generating cell lines which produce the recombinant protein at high levels. The physiological changes accompanying t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::85b3d958c255a7ac8a21139da476a28d
https://pubmed.ncbi.nlm.nih.gov/24108600
https://pubmed.ncbi.nlm.nih.gov/24108600
Publikováno v:
Proceedings of the 14th Asia Pacific Confederation of Chemical Engineering Congress.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cab86f8b2cd6cc71b7096820f5e38ff6
https://doi.org/10.3850/978-981-07-1445-1_818
https://doi.org/10.3850/978-981-07-1445-1_818