Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Nitu Bansal"'
Autor:
Hatem E. Sabaawy, Joseph Bertino, Robert S. DiPaola, Thomas W. Davis, Isaac Y. Kim, Mark N. Stein, John Kerrigan, Daniel Medina, Hua Zhong, Young-Choon Moon, Nadiya Sydorenko, Liangxian Cao, Daniel Jones, Michele Patrizii, Eric Huselid, Kathleen Flaherty, Stephani Davis, Shamila Yusuff, Monica Bartucci, Nitu Bansal
Purpose: Current prostate cancer management calls for identifying novel and more effective therapies. Self-renewing tumor-initiating cells (TICs) hold intrinsic therapy resistance and account for tumor relapse and progression. As BMI-1 regulates stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925153583244741b63d2ce956090ae1f
https://doi.org/10.1158/1078-0432.c.6527079.v1
https://doi.org/10.1158/1078-0432.c.6527079.v1
Autor:
Hatem E. Sabaawy, Joseph Bertino, Robert S. DiPaola, Thomas W. Davis, Isaac Y. Kim, Mark N. Stein, John Kerrigan, Daniel Medina, Hua Zhong, Young-Choon Moon, Nadiya Sydorenko, Liangxian Cao, Daniel Jones, Michele Patrizii, Eric Huselid, Kathleen Flaherty, Stephani Davis, Shamila Yusuff, Monica Bartucci, Nitu Bansal
Supplementary data Figure S1. Functional role(s) of BMI-1 in PCa. Figure S2. BMI-1 expression in subpopulations of DU145 cells. Figure S3. Pharmacological inhibition of BMI-1. Figure S4. Molecular and cellular effects of pharmacological targeting of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ffced9ef7f9a1c40d742ab4b16fc4aa
https://doi.org/10.1158/1078-0432.22468857
https://doi.org/10.1158/1078-0432.22468857
Autor:
Nitu Bansal, Tazeem Shaik, Debabrata Banerjee, John E. Kerrigan, Zoltan Szekely, Joseph R. Bertino, Kathleen W. Scotto, Tamara Minko, Gulam M. Rather, Olga B. Garbuzenko, Emine Ercikan Abali
Publikováno v:
Oncotarget
E2F1-3a overexpression due to amplification or to mutation or loss of the retinoblastoma gene, induces genes involved in DNA synthesis and leads to abnormal cellular proliferation, tumor growth, and invasion. Therefore, inhibiting the overexpression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115d760278c0e611a3183929e1c5b9e4
http://europepmc.org/articles/PMC6161789
http://europepmc.org/articles/PMC6161789
Autor:
John E. Kerrigan, Nitu Bansal, Kathleen W. Scotto, Tazeem Shaik, Olga B. Garbuzenko, Debabrata Banerjee, Emine Ercikan Abali, Xiaoqi Xie, Tamara Minko, Joseph R. Bertino, Nadine Johnson-Farley
Publikováno v:
Oncotarget
// Xiaoqi Xie 1 , Nitu Bansal 1 , Tazeem Shaik 1 , John E. Kerrigan 1 , Tamara Minko 2 , Olga Garbuzenko 2 ,Emine Ercikan Abali 3 , Nadine Johnson-Farley 1 , Debabrata Banerjee 1 , Kathleen W. Scotto 1 and Joseph R Bertino 1 1 Rutgers Cancer Institut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee27838e935d30501cf16a6956f362a
https://doi.org/10.18632/oncotarget.1809
https://doi.org/10.18632/oncotarget.1809
Publikováno v:
Oncotarget
Recent epidemiological studies showed that metformin, a widely used anti-diabetic drug might prevent certain cancers. Metformin also has an anti-proliferative effect in preclinical studies of both hematologic malignancies as well as solid cancers and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3effcb2c7b933354a6e20de7a702dc6
http://europepmc.org/articles/PMC4558154
http://europepmc.org/articles/PMC4558154
Autor:
Nadine Johnson Farley, Jonathan Lewis, Nitu Bansal, Hagop Youssoufian, Lisa Y. Wu, Joseph R. Bertino
Publikováno v:
Molecular Cancer Therapeutics. 14:23-30
Prostate cancer is the leading cause of cancer-related death in men in the United States. A major cause of drug resistance in prostate and other epithelial tumors may be due to the presence of a fraction of tumor cells that retain the ability to init
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe54123d0954f92f35b965679b75fd2c
https://doi.org/10.1158/1535-7163.mct-13-1040
https://doi.org/10.1158/1535-7163.mct-13-1040
Autor:
Thomas W. Comollo, Stanley G. Kimani, Kamalendra Singh, Joseph R. Bertino, Sergei V. Kotenko, Vladyslav Kholodovych, Youyi Peng, Nitu Bansal, Sushil Kumar, Raymond B. Birge, Stefan G. Sarafianos, William J. Welsh
Publikováno v:
Scientific Reports
TAM receptors (Tyro-3, Axl, and Mertk) are a family of three homologous type I receptor tyrosine kinases that are implicated in several human malignancies. Overexpression of TAMs and their major ligand Growth arrest-specific factor 6 (Gas6) is associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2613827f3f3ff1d01b85e0e09be50cf
https://doi.org/10.1038/srep43908
https://doi.org/10.1038/srep43908
Autor:
Stephani A. Davis, Nitu Bansal, Irina V. Tereshchenko, Isaac Yi Kim, Hua Zhong, Tulin Budak-Alpdogan, Hatem E. Sabaawy, Mark N. Stein, Joseph R. Bertino, Robert S. DiPaola
Publikováno v:
The Prostate. 74:187-200
BACKGROUND Prostate tumor-initiating cells (TICs) have intrinsic resistance to current therapies. TICs are commonly isolated by cell sorting or dye exclusion, however, isolating TICs from limited primary prostate cancer (PCa) tissues is inherently in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61351dd3341757593323308754aeef77
https://doi.org/10.1002/pros.22740
https://doi.org/10.1002/pros.22740
Autor:
Prajwal P. Nandekar, Abhay T. Sangamwar, Vijay Rathod, Neelagiri Soumya, Leena B. Labhsetwar, Khaled M. Tumbi, Nitu Bansal, Sushma Singh
Publikováno v:
Medicinal Chemistry Research. 22:3728-3742
The benzothiazole scaffold has been reported to have antitumor activity in tumor-sensitive cell lines by proposed mechanism of CYP1A1 induction. CYP1A1 has been shown to participate in metabolism of benzothiazole scaffold to its reactive metabolites.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d88dbc42369ab83b57eddedc247fd42d
https://doi.org/10.1007/s00044-012-0364-8
https://doi.org/10.1007/s00044-012-0364-8
Autor:
Joseph R. Bertino, Isaac Yi Kim, Hatem E. Sabaawy, Liangxian Cao, Thomas W. Davis, Kathleen Flaherty, Young-Choon Moon, Shamila Yusuff, Mark N. Stein, Daniel Jones, Monica Bartucci, Stephani A. Davis, Hua Zhong, John Kerrigan, Michele Patrizii, Eric Huselid, Nitu Bansal, Nadiya Sydorenko, Daniel J. Medina, Robert S. DiPaola
Purpose: Current prostate cancer management calls for identifying novel and more effective therapies. Self-renewing tumor-initiating cells (TICs) hold intrinsic therapy resistance and account for tumor relapse and progression. As BMI-1 regulates stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b26fc350e2da4cf3c2a85b3dff856ff6
https://europepmc.org/articles/PMC5159329/
https://europepmc.org/articles/PMC5159329/