Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Nitsan Kozlovsky"'
Publikováno v:
European Journal of Psychotraumatology, Vol 3, Iss 0, Pp 1-1 (2012)
Rationale : The activation of the neuroendocrine systems is a basic response to environmental perturbations, which threaten homeostasis. The HPA-axis is one of the primary effector systems, which functions to minimize deviations from the homeostatic
Externí odkaz:
https://doaj.org/article/feb0aaefe03e4588b4ed47748dd5703f
Publikováno v:
European Journal of Psychotraumatology, Vol 3, Iss 0, Pp 1-1 (2012)
Rationale: In a previous study, we examined the effect of a single intervention with high-dose corticosterone, 1h after predator stress-exposure (PSS), and showed a significant reduction in the incidence of PTSD-like behaviors and improved resilience
Externí odkaz:
https://doaj.org/article/bf3d0d47573a4313a01b4e9b57cd2e48
Publikováno v:
European Neuropsychopharmacology. 22:205-221
In mammals, the circadian and stress systems are involved in adaptation to predictable and unpredictable stimuli, respectively. A series of experiments examined the relationship between stress-induced posttraumatic stress (PTSD)-like behavioral respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0099a3d6fc90096ef0614a5406dd6f80
https://doi.org/10.1016/j.euroneuro.2011.07.012
https://doi.org/10.1016/j.euroneuro.2011.07.012
Publikováno v:
Neuropharmacology. 62:715-724
In humans, the diagnosis of PTSD is made only if an individual exhibits a certain number of symptoms from each of three quite well defined symptom clusters over a certain period of time. Animal behavioral studies, however, have generally tended to ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4e9bbfed8a5451681799f594b4d925
https://doi.org/10.1016/j.neuropharm.2011.04.023
https://doi.org/10.1016/j.neuropharm.2011.04.023
Publikováno v:
European Neuropsychopharmacology. 19:759-771
Background Activation of glucocorticoid receptors (GR) increases expression of the mitogen-activated protein kinase (MAPK) pathway leading to increased expression of Zif/268, an effector immediate early gene involved in cellular growth, intracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777f9ce0e53a904ea2e6f990424289c3
https://doi.org/10.1016/j.euroneuro.2009.04.009
https://doi.org/10.1016/j.euroneuro.2009.04.009
Publikováno v:
Biological Psychiatry. 60:767-776
Background Paradoxical changes in memory represent a troublesome characteristic of posttraumatic stress disorder (PTSD). Exceptionally vivid intrusive memories of some aspects of the trauma are mingled with patchy amnesia regarding other important as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf4c8ca1c372c3c488469e17617cace
https://doi.org/10.1016/j.biopsych.2006.03.013
https://doi.org/10.1016/j.biopsych.2006.03.013
Publikováno v:
European Neuropsychopharmacology. 15:1-11
Glycogen synthase kinase-3 (GSK-3) is a protein kinase highly abundant in brain and involved in signal transduction cascades, particularly neurodevelopment. Its activity and protein levels have been reported to be over 40% lower in postmortem frontal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcb775e77e6c7e3ef29e2b5f9b2d920e
https://doi.org/10.1016/j.euroneuro.2004.02.003
https://doi.org/10.1016/j.euroneuro.2004.02.003
Autor:
Nitsan Kozlovsky, Joel E. Kleinman, C. Shanon-Weickert, Eva Tomaskovic-Crook, Galila Agam, Robert H. Belmaker
Publikováno v:
Journal of Neural Transmission. 111:1583-1592
Glycogen Synthase Kinase (GSK)-3 is a ubiquitous serine/threonine protein kinase highly abundant in brain which plays a key role in neural development and neuron survival. We have previously reported that GSK-3beta protein levels and GSK-3 activity a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61787106fd193c7b076fe22b0c5e1912
https://doi.org/10.1007/s00702-004-0166-3
https://doi.org/10.1007/s00702-004-0166-3
Autor:
Galila, Agam, Galit, Shaltiel, Nitsan, Kozlovsky, Hady, Shimon, R H, Belmaker, Galit, Shatiel
Publikováno v:
Journal of Psychiatric Research. 37:433-442
Despite considerable ongoing efforts at the epidemiological, genetic and molecular level, the etiology of bipolar disorder had not yet been elucidated. To study possible contributing components to the pathophysiology of this disorder, we have hypothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37fe2657a68f7b601dec65d014049c5e
https://doi.org/10.1016/s0022-3956(03)00044-x
https://doi.org/10.1016/s0022-3956(03)00044-x
Publikováno v:
The International Journal of Neuropsychopharmacology. 6:117-120
Glycogen synthase kinase (GSK)-3 β protein levels and GSK-3 activity were previously found to be over 40% reduced in the post-mortem prefrontal cortex of schizophrenic patients. Lithium and valproate have been reported to selectively inhibit GSK-3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf784a9f5f8be8f148d2efcf43146fa8
https://doi.org/10.1017/s1461145703003353
https://doi.org/10.1017/s1461145703003353