Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Nitroaspirin"'
Publikováno v:
Journal of Acute Disease, Vol 5, Iss 5, Pp 364-381 (2016)
Inflammation mediators, prostaglandins are causing inflammation, pain and pyrexia in the body. Synthesis of these mediators can be effectively blocked by administering the nonsteroidal anti-inflammatory drugs (NSAIDs). The NSAIDs had age-old history
Externí odkaz:
https://doaj.org/article/bca616ef31914891a31f6266c0882cc7
Publikováno v:
Journal of Acute Disease, Vol 5, Iss 5, Pp 364-381 (2016)
Inflammation mediators, prostaglandins are causing inflammation, pain and pyrexia in the body. Synthesis of these mediators can be effectively blocked by administering the non-steroidal anti-inflammatory drugs (NSAIDs). The NSAIDs had age-old history
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c8ca6ec63cb302565c4c6b6c121b08
http://www.sciencedirect.com/science/article/pii/S2221618916301081
http://www.sciencedirect.com/science/article/pii/S2221618916301081
Autor:
Ian L. Megson, Mark R. Miller
Publikováno v:
British Journal of Pharmacology. 151:305-321
During the 1980s, the free radical, nitric oxide (NO), was discovered to be a crucial signalling molecule, with wide-ranging functions in the cardiovascular, nervous and immune systems. Aside from providing a credible explanation for the actions of o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9588aa502bbccd6efeac7a889b31ee17
https://doi.org/10.1038/sj.bjp.0707224
https://doi.org/10.1038/sj.bjp.0707224
Autor:
Giancarlo Aldini, Marina Carini, Roberto Maffei Facino, Angela Piccoli, Marica Orioli, Giuseppe Rossoni
Publikováno v:
Life Sciences. 74:3291-3305
The metabolic fate of nitric oxide (NO) released from nitroaspirin, benzoic acid, 2-(acetyloxy)-3-[(nitrooxy)methyl]phenyl ester (NCX 4016), the lead compound of a new class of NO-releasing non steroidal anti-inflammatory drugs (NO-NSAIDs), has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::542e05858395c865cc24817bbb7e7279
https://doi.org/10.1016/j.lfs.2003.11.018
https://doi.org/10.1016/j.lfs.2003.11.018
Autor:
Bruce F. Kaufman, Vijay Kumar Kutala, Ashish Sharma, Louis J. Ignarro, Narasimham L. Parinandi, Timothy D. Eubank, Periannan Kuppusamy, Clay B. Marsh
Publikováno v:
Antioxidantsredox signaling. 9(11)
We recently reported that NCX-4016, a derivative of aspirin containing a nitro moiety that releases nitric oxide (NO) in a sustained fashion in biologic systems, is a potent cytotoxic agent inhibiting the proliferation of cisplatin-resistant human ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71fdccba31538aa3077e2d118c3de330
https://pubmed.ncbi.nlm.nih.gov/17760507
https://pubmed.ncbi.nlm.nih.gov/17760507
Publikováno v:
Trends in cardiovascular medicine. 15(8)
The increased expression and activity of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex has emerged as a major common factor in the etiology of all forms of cardiovascular diseases since the upregulation of intravascular NADP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf7ba1ecbc6f4bb82e5ff58bbe73d019
https://pubmed.ncbi.nlm.nih.gov/16297764
https://pubmed.ncbi.nlm.nih.gov/16297764
Autor:
Gustavo, Reichenbach, Reichenbach, Gustavo, Stefania, Momi, Momi, Stefania, Paolo, Gresele, Gresele, Paolo
Publikováno v:
Current drug targets. Cardiovascularhaematological disorders. 5(1)
Nitric oxide (NO) is a small gaseous molecule with an odd number of electrons and is rather soluble in hydrophobic phases. It was once known for its toxicity in the environment and for its applications in meat curing. After 1980 its importance was di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d269b1c06c54e295b034f087e0e1ff
https://pubmed.ncbi.nlm.nih.gov/15720224
https://pubmed.ncbi.nlm.nih.gov/15720224
Despite great advantages in antithrombotic treatments, important limitations of the presently available drugs encourage the search of more effective agents. Within the cardiovascular system, nitric oxide exerts several activities which may have an an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2a83b6304d6ff7007490869cdeab122
http://hdl.handle.net/11391/164518
http://hdl.handle.net/11391/164518
