Výsledky vyhledávání - "Nitric Oxide Synthase Type II/metabolism"

Pregabalin Ameliorates Lipopolysaccharide-Induced Pancreatic Inflammation in Aged Rats

Autor: Ozlem Ozmen, Senay Topsakal

Publikováno v: Endocrine, Metabolic & Immune Disorders - Drug Targets. 19:1141-1147

Objective: The aim of this study was to examine pancreatic pathology and the prophylactic effects of pregabalin in lipopolysaccharide (LPS) induced sepsis model in aged rats. Methods: Twenty-four female, one-year-old, Wistar Albino rats were assigned

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f9114be52657faf470b2e0452280f8
https://doi.org/10.2174/1871530319666190306095532

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Inflammation leads to distinct populations of extracellular vesicles from microglia

Autor: Christopher J.R. Dunning, Tomas Deierborg, Bettina Hjelm Clausen, Yiyi Yang, Antonio Boza-Serrano, Kate Lykke Lambertsen

Publikováno v: Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-19 (2018)
Journal of Neuroinflammation
Yang, Y, Boza-Serrano, A, Dunning, C J R, Clausen, B H, Lambertsen, K L & Deierborg, T 2018, ' Inflammation leads to distinct populations of extracellular vesicles from microglia ', Journal of Neuroinflammation, vol. 15, 168 . https://doi.org/10.1186/s12974-018-1204-7

Background Activated microglia play an essential role in inflammatory responses elicited in the central nervous system (CNS). Microglia-derived extracellular vesicles (EVs) are suggested to be involved in propagation of inflammatory signals and in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa5b9f02a66c45696b513383261ae0bf
http://link.springer.com/article/10.1186/s12974-018-1204-7

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Aberrant up-regulation of iNOS/NO system is correlated with an increased abundance of Foxp3+ cells and reduced effector/memory cell markers expression during colorectal cancer: immunomodulatory effects of cetuximab combined with chemotherapy

Autor: Sonia Ait-Younes, Mourad Belkhelfa, Chafia Touil-Boukoffa, Yvan de Launoit, Hassen Mahfouf, Hayet Rafa, Nadira Delhem, Hayat Ait-Kaci, Olivier Moralès, Sabah Hetit, Oussama Medjeber, Sarra Benkhelifa, Said Belhadef

Publikováno v: Inflammopharmacology
Inflammopharmacology, Springer Verlag, 2019, 27 (4), pp.685-700. ⟨10.1007/s10787-019-00566-9⟩
Inflammopharmacology, 2019, 27 (4), pp.685-700. ⟨10.1007/s10787-019-00566-9⟩

International audience; Colorectal cancer (CRC) remains the most cancer type related to chronic inflammation; however, the mechanisms that link inflammation to CRC development and progression are still poorly understood. Our study aimed to investigat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c14e2c54400f0d81e84b20996df275
https://hal.archives-ouvertes.fr/hal-03059991

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Leishmania amazonensis downregulates macrophage iNOS expression via Histone Deacetylase 1 (HDAC1): a novel parasite evasion mechanism

Autor: Nicolas Fasel, Ulisses Gazos Lopes, Gabrielle B L Silva, Áislan de Carvalho Vivarini, Carolina Torturella Rath, José Vitorino dos Santos, Renata M. Pereira, Teresa Cristina Calegari-Silva, Alessandra Mattos Saliba, Carlos Eduardo Pereira Corbett, Karina Luiza Dias-Teixeira, Amanda S S Pacheco, Charlene A S Pinto, Claudia Maria de Castro Gomes

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
European journal of immunology, vol. 48, no. 7, pp. 1188-1198

The induced expression of nitric oxide synthase (iNOS) controls the intracellular growth of Leishmania in infected macrophages. Histones deacetylases (HDACs) negatively regulate gene expression through the formation of complexes containing transcript

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf8ac4e7c7cd8865a82b83be8e071c51

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PARP1 is required for adhesion molecule expression in atherogenesis

Autor: Michael O. Hottiger, François Mach, Barbara E. Stähli, Christian M. Matter, Monika Gersbach, Christine Lohmann, Vincent Braunersreuther, Felix C. Tanner, Thomas F. Lüscher, Jan Borén, Giovanni G. Camici, Paul O. Hassa, Tobias von Lukowicz, Bernhard Odermatt

Publikováno v: Cardiovascular Research, Vol. 78, No 1 (2008) pp. 158-66

AIMS: Atherosclerosis is the leading cause of death in Western societies and a chronic inflammatory disease. However, the key mediators linking recruitment of inflammatory cells to atherogenesis remain poorly defined. Poly(ADP-ribose) polymerase 1 (P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2287753e12011f9dbe9d333930ba633
http://doc.rero.ch/record/291728/files/cvm110.pdf

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Participation of hippocampal nitric oxide synthase and soluble guanylate cyclase in the modulation of behavioral responses elicited by the rat forced swimming test

Autor: Amanda J. Sales, Sâmia R.L. Joca, Vinicius A. Hiroaki-Sato

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Sales, A J, Hiroaki-Sato, V A & Joca, S R L 2017, ' Participation of hippocampal nitric oxide synthase and soluble guanylate cyclase in the modulation of behavioral responses elicited by the rat forced swimming test ', Behavioural Pharmacology, vol. 28, no. 1, pp. 19-29 . https://doi.org/10.1097/FBP.0000000000000263

Systemic or hippocampal administration of nitric oxide (NO) synthase inhibitors induces antidepressant-like effects in animals, implicating increased hippocampal levels of NO in the neurobiology of depression. However, the role played by different NO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d8fbd15a133d78658f13f169607c59

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All-Trans Retinoic Acid Modulates TLR4/NF- κ B Signaling Pathway Targeting TNF- α and Nitric Oxide Synthase 2 Expression in Colonic Mucosa during Ulcerative Colitis and Colitis Associated Cancer

Autor: M’hamed Nakmouche, Said Belhadef, Aziza Boukercha, Olivier Moralès, Hassen Mahfouf, Sonia Ait-Younes, Hayet Rafa, Sarra Benkhelifa, Ryma Toumi, Mourad Belkhelfa, Yvan de Launoit, Chafia Touil-Boukoffa, Imene Soufli, Nadira Delhem, Houria Saoula

Publikováno v: Mediators of Inflammation
Mediators of Inflammation, 2017, 2017, pp.7353252. ⟨10.1155/2017/7353252⟩
Mediators of Inflammation, Vol 2017 (2017)
Mediators of Inflammation, Hindawi Publishing Corporation, 2017, 2017, pp.7353252. ⟨10.1155/2017/7353252⟩
Mediators of Inflammation, Hindawi Publishing Corporation, 2017, 2017, pp.1-16. ⟨10.1155/2017/7353252⟩

Colitis associated cancer (CAC) is the colorectal cancer (CRC) subtype that is associated with bowel disease such as ulcerative colitis (UC). The data on role of NF-κB signaling in development and progression of CAC were derived from preclinical stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61aabb23e503ebb00e3a943766bdaf55
https://hal.science/hal-02391613/file/AllTrans_Retinoic_acid_modulates_TLR4NFB_signaling.pdf

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Evaluation of anti-proliferative and anti-inflammatory activities of Pelagia noctiluca venom in Lipopolysaccharide/Interferon-γ stimulated RAW264.7 macrophages

Autor: Rabiaa M. Sghaier, Yosra Ayed, Dhafer Laouini, Hassen Bacha

Publikováno v: Biomedicine and Pharmacotherapy
Biomedicine and Pharmacotherapy, Elsevier Masson, 2016, 84, pp.1986-1991. 〈10.1016/j.biopha.2016.11.010 〉
Biomedicine and Pharmacotherapy, Elsevier Masson, 2016, 84, pp.1986-1991. ⟨10.1016/j.biopha.2016.11.010⟩

International audience; Components of Pelagia noctiluca (P. noctiluca) venom were evaluated for their anticancer and nitric Oxide (NO) inhibition activities. Three fractions, out of four, obtained by gel filtration on Sephadex G75 of P. noctiluca ven

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf245dbc45e5a060c082c657154154d
https://hal-riip.archives-ouvertes.fr/pasteur-01455071

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Increased nitric oxide (NO) pathway metabolites in the vitreous fluid of patients with rhegmatogenous retinal detachment or diabetic traction retinal detachment

Autor: Hans M.H. van Eijk, Alfons G.H. Kessels, Ellen C. La Heij, Roselie M.H. Diederen, Nicolaas E. P. Deutz, Fred Hendrikse

Publikováno v: Graefe s archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 244(6), 683-8. Springer Verlag
Graefe's Archive for Clinical and Experimental Ophthalmology, 244(6), 683-688. Springer Verlag

BACKGROUND: Nitric oxide (NO) plays a significant role in physiological and pathological processes in the retina. In the L-arginine-NO pathway, NO synthase (NOS) converts L-arginine to NO and L-citrulline. Increased NO production, mediated by inducib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7332583d94d8a52b798aa474d702a74e
https://doi.org/10.1007/s00417-005-0141-1

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IL-23/IL-17A Axis Correlates with the Nitric Oxide Pathway in Inflammatory Bowel Disease: Immunomodulatory Effect of Retinoic Acid

Autor: Imene Soufli, Chafia Touil-Boukoffa, Hayet Rafa, Nadira Delhem, Ryma Toumi, Houria Saoula, Yvan de Launoit, M’hamed Nakmouche, Olivier Moralès, Oussama Medjeber, Mourad Belkhelfa

Publikováno v: Journal of Interferon and Cytokine Research
Journal of Interferon and Cytokine Research, Mary Ann Liebert, 2013, 33 (7), pp.355-368. ⟨10.1089/jir.2012.0063⟩

International audience; Inflammatory bowel diseases (IBDs) are chronic inflammatory diseases of the gastrointestinal tract, which are clinically present as 1 of the 2 disorders, Crohn's disease (CD) or ulcerative colitis (UC) (Rogler 2004). The immun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a681e8219310a30fbf46f18c46e3e251
https://hal.archives-ouvertes.fr/hal-02395835

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