Zobrazeno 1 - 10
of 405
pro vyhledávání: '"Nitrenium ion"'
Publikováno v:
Genes and Environment, Vol 44, Iss 1, Pp 1-10 (2022)
Abstract Background Aromatic amines, often used as intermediates for pharmaceutical synthesis, may be mutagenic and therefore pose a challenge as metabolites or impurities in drug development. However, predicting the mutagenicity of aromatic amines u
Externí odkaz:
https://doaj.org/article/e0da8f74e3f1411f9838ca109d6ab47a
Autor:
Xing-Hua Xia, Han Hao, Wenjun Zhang, Qiao Yu, Ting Wang, Hang Gao, Jing-Juan Xu, Jun Hu, Hong-Yuan Chen, Yun Chen, Nan Zhang
Publikováno v:
Angewandte Chemie International Edition. 60:18494-18498
A novel mass spectrometric method for probing the flash chemistry of electrogenerated reactive intermediates was developed based on rapid collision mixing of electrosprayed microdroplets by using a theta-glass capillary. The two individual microchann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ecb8cdc5b382d6a2e4e725e916e9979
https://doi.org/10.1002/anie.202106945
https://doi.org/10.1002/anie.202106945
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 21, p 5512 (2019)
Nitrenium ions are common reactive intermediates with high activities towards some biological nucleophiles. In this paper, we employed femtosecond transient absorption (fs-TA) and nanosecond transient absorption (ns-TA) as well as nanosecond time-res
Externí odkaz:
https://doaj.org/article/1e8122e38d344e96978bf2d4a20f51f8
Publikováno v:
Molecules, Vol 23, Iss 12, p 3182 (2018)
Nitrenium ions are important reactive intermediates in chemistry and biology. In this work, femtosecond and nanosecond transient absorption (fs-TA and ns-TA) along with nanosecond time-resolved resonance Raman (ns-TR3) experiments were employed to ex
Externí odkaz:
https://doaj.org/article/84fb4be75208491cb60c2e5f29de1eb8
Akademický článek
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Publikováno v:
Chemistry – A European Journal. 26:8871-8874
Hydride abstraction from diarylamines with the trityl ion is explored in an attempt to generate a stable diarylnitrenium ion, Ar2 N+ . Sequential H-atom abstraction reactions ensue. The first H-atom abstraction leads to intensely colored aminium radi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c90a0ed8888967786dfa8eab7aad6c9
https://doi.org/10.1002/chem.202000930
https://doi.org/10.1002/chem.202000930
Autor:
Andrea N. Zeppuhar, Daniel E. Falvey
Publikováno v:
The Journal of Organic Chemistry. 85:8844-8850
The behavior of the N,N-di(4-bromophenyl)nitrenium ion under acidic aqueous conditions was examined via laser flash photolysis experiments. A long-lived species forms and can be assigned as the cation radical or the dication. This species is unreacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b4fcacb2cfda2d645be9e7d062fb594
https://doi.org/10.1021/acs.joc.0c00686
https://doi.org/10.1021/acs.joc.0c00686
Autor:
Xuechen Li, David Lee Phillips, Zhiyuan Zhu, Yue Zhang, Lili Du, Wenjian Tang, Shun-Cheung Cheng, Zhiping Yan
Publikováno v:
The Journal of Organic Chemistry. 85:8792-8797
Arylnitrenium ions have gained attention for their high reactivity toward guanosine, which in some cases has been linked to carcinogenesis. Although many studies have examined covalent addition reactions between arylnitrenium ions and guanosine, ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92be62aa024d7929698025e3dd0e48f
https://doi.org/10.1021/acs.joc.0c00517
https://doi.org/10.1021/acs.joc.0c00517
Autor:
Ying Peng, Zhengyu Zhang, Lingling Han, Yanhong Zhao, Yudi Jia, Wei Li, Jiang Zheng, Xiucai Guo
Publikováno v:
Chemical Research in Toxicology. 32:2459-2465
Tofacitinib (TFT) is used for the treatment of moderately and severely active rheumatoid arthritis. Unfortunately, TFT was reported to induce leukopenia, and the underlying mechanisms remain unclear. The present study demonstrated that TFT was oxidiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::452e2ea34812da82296b613540453c9f
https://doi.org/10.1021/acs.chemrestox.9b00280
https://doi.org/10.1021/acs.chemrestox.9b00280
Publikováno v:
ChemistrySelect. 4:7010-7014
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd6f01e5cdfe72326d27131f7eaece31
https://doi.org/10.1002/slct.201900944
https://doi.org/10.1002/slct.201900944