Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Nitish K Mishra"'
Autor:
Uppala Radhakrishna, Samet Albayrak, Rita Zafra, Alosh Baraa, Sangeetha Vishweswaraiah, Avinash M Veerappa, Deepthi Mahishi, Nazia Saiyed, Nitish K Mishra, Chittibabu Guda, Rouba Ali-Fehmi, Ray O Bahado-Singh
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0200229 (2019)
Ventricular Septal Defect (VSD), the most common congenital heart defect, is characterized by a hole in the septum between the right and left ventricles. The pathogenesis of VSD is unknown in most clinical cases. There is a paucity of data relevant t
Externí odkaz:
https://doaj.org/article/7c4ef876ecad48a2894b5d2a4a5b7d6f
Autor:
Uppala Radhakrishna, Sangeetha Vishweswaraiah, Avinash M Veerappa, Rita Zafra, Samet Albayrak, Prajna H Sitharam, Nazia M Saiyed, Nitish K Mishra, Chittibabu Guda, Ray Bahado-Singh
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203893 (2018)
Tetralogy of Fallot (TOF) is the most common Critical Congenital Heart Defect (CCHD). The etiology of TOF is unknown in most cases. Preliminary data from our group and others suggest that epigenetic changes may play an important role in CHD. Epidemio
Externí odkaz:
https://doaj.org/article/2dcee422c29642fabbb659704358d1ff
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119383 (2015)
Breast cancers exhibit highly heterogeneous molecular profiles. Although gene expression profiles have been used to predict the risks and prognostic outcomes of breast cancers, the high variability of gene expression limits its clinical application.
Externí odkaz:
https://doaj.org/article/cc37830391d94cd79772708bda12b8b3
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100278 (2014)
Membrane transport proteins (transporters) move hydrophilic substrates across hydrophobic membranes and play vital roles in most cellular functions. Transporters represent a diverse group of proteins that differ in topology, energy coupling mechanism
Externí odkaz:
https://doaj.org/article/2e75e5942e71473d9c2ca290554811fd
Publikováno v:
Cells, Vol 12, Iss 2, p 328 (2023)
Fetal alcohol spectrum disorders (FASDs) are associated with systemic inflammation and neurodevelopmental abnormalities. Several candidate genes were found to be associated with fetal alcohol exposure (FAE)-associated behaviors, but a sex-specific co
Externí odkaz:
https://doaj.org/article/3ac395bfe0834d4c9b83d834c7b41bed
Autor:
Hamid Band, Vimla Band, Emad A. Rakha, Srikumar Raja, Jane L. Meza, Yuri M. Sheinin, Chittibabu Guda, Nitish K. Mishra, Matthew D. Storck, Rokaya El-Ansari, Dena Ahmed, Wei An, Robert J. Clubb, Tameka A. Jennings, Sameer Mirza, Insha Mushtaq, Timothy A. Bielecki, Bhopal Mohapatra, Haitao Luan
Tables and Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a41a28cb363aee8327b2458c136114a
https://doi.org/10.1158/0008-5472.22417346.v1
https://doi.org/10.1158/0008-5472.22417346.v1
Autor:
Matthew J. Kling, Varun Kesherwani, Nitish K. Mishra, Gracey Alexander, Erin M. McIntyre, Sutapa Ray, Kishore B. Challagundla, Shantaram S. Joshi, Don W. Coulter, Nagendra K. Chaturvedi
Publikováno v:
Journal of experimentalclinical cancer research : CR. 41(1)
Background Medulloblastoma (MB) patients with MYC oncogene amplification or overexpression exhibit extremely poor clinical outcomes and respond poorly to current therapies. Epigenetic deregulation is very common in MYC-driven MB. The bromodomain extr
Autor:
Ariadna Forray, Uppala Radhakrishna, Chittibabu Guda, Wade H. Berrettini, Buket Aydas, Jacqueline Macknis, Sandeep Kumar, Srinivas B. Muvvala, Ray O. Bahado-Singh, David J. Carey, Sangeetha Vishweswaraiah, Raghu Metpally, Nitish K. Mishra, Richard C. Crist, Lavanya V. Uppala, Marta Szymanska, Fozia Saleem-Rasheed
Publikováno v:
Genomics. 113:1127-1135
Opioid abuse during pregnancy can result in Neonatal Opioid Withdrawal Syndrome (NOWS). We investigated genome-wide methylation analyses of 96 placental tissue samples, including 32 prenatally opioid-exposed infants with NOWS who needed therapy (+Opi
Autor:
Shantaram S. Joshi, Jasjit K. Banwait, Kishor K. Bhakat, Chittibabu Guda, Neetha Nanoth Vellichirammal, Mathew J. Kling, Shrabasti Roychoudhury, Sameer Mirza, Abrar Albahrani, Vimla Band, Nitish K. Mishra, You Li
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 19, Iss, Pp 1379-1398 (2020)
Molecular Therapy: Nucleic Acids, Vol 19, Iss, Pp 1379-1398 (2020)
Gene fusions that contribute to oncogenicity can be explored for identifying cancer biomarkers and potential drug targets. To investigate the nature and distribution of fusion transcripts in cancer, we examined the transcriptome data of about 9,000 p
Autor:
Ray Bahado-Singh, Perry Friedman, Ciara Talbot, Buket Aydas, Siddesh Southekal, Nitish K. Mishra, Chittibabu Guda, Ali Yilmaz, Uppala Radhakrishna, Sangeetha Vishweswaraiah
Publikováno v:
American Journal of Obstetrics and Gynecology. 228:76.e1-76.e10
DNA cytosine nucleotide methylation (epigenomics and epigenetics) is an important mechanism for controlling gene expression in cardiac development. Combined artificial intelligence and whole-genome epigenomic analysis of circulating cell-free DNA in