Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Nitin Udar"'
Autor:
Kevin Schneider, Marilyn Chwa, Shari R. Atilano, Sonali Nashine, Nitin Udar, David S. Boyer, S. Michal Jazwinski, Michael V. Miceli, Anthony B. Nesburn, Baruch D. Kuppermann, M. Cristina Kenney
Publikováno v:
FASEB BioAdvances, Vol 4, Iss 10, Pp 675-689 (2022)
Abstract Activation of the Simulator of Interferon Genes (STING) system by mitochondrial (mt) DNA can upregulate type 1 interferon genes and enhance immune responses to combat bacterial and viral infections. In cancers, the tumor‐derived DNA activa
Externí odkaz:
https://doaj.org/article/09bf357e9bfd42d796eda35f47c0bc9b
Autor:
Shari R Atilano, Daniel H Lee, Paula S Fukuhara, Marilyn Chwa, Anthony B Nesburn, Nitin Udar, Cristina Kenney
Publikováno v:
Journal of Ophthalmic & Vision Research, Vol 14, Iss 1, Pp 62-70 (2019)
Purpose: To compare the levels of gene expression for enzymes involved in production and elimination of reactive oxygen/nitrogen species (ROS/RNS) in normal human corneal cells (NL cells) with those in human corneal cells with keratoconus (KC cells)
Externí odkaz:
https://doaj.org/article/6ad195d8ae534db09f9ff1c9f6e66a31
Autor:
Steven Chang, Lata Singh, Kunal Thaker, Sina Abedi, Mithalesh K. Singh, Tej H. Patel, Marilyn Chwa, Shari R. Atilano, Nitin Udar, Daniela Bota, Maria Cristina Kenney
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6687 (2022)
The aim of this study was to determine the role of retrograde signaling (mitochondria to nucleus) in MCF7 breast cancer cells. Therefore, in the present study, MCF7-H and MCF7-J cybrids were produced using the mitochondria from the same H and J indiv
Externí odkaz:
https://doaj.org/article/1126e3bd5f09411dab23c42fbd662e9e
Autor:
Shari R Atilano, Nitin Udar, Timothy A Satalich, Viraat Udar, Marilyn Chwa, M Cristina Kenney
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0246114 (2021)
PurposeMitochondrial (mt) DNA damage is associated with age-related macular degeneration (AMD) and other human aging diseases. This study was designed to quantify and characterize mtDNA low-frequency heteroplasmy single nucleotide polymorphisms (SNPs
Externí odkaz:
https://doaj.org/article/35dabe7f52a0467a930d0acb2e3c19c2
Autor:
Sina Abedi, Gregory Yung, Shari R. Atilano, Kunal Thaker, Steven Chang, Marilyn Chwa, Kevin Schneider, Nitin Udar, Daniela Bota, M. Cristina Kenney
Publikováno v:
PeerJ, Vol 8, p e9908 (2020)
Background Drug therapy yields different results depending on its recipient population. Cisplatin, a commonly used chemotherapeutic agent, causes different levels of resistance and side effects for different patients, but the mechanism(s) are present
Externí odkaz:
https://doaj.org/article/ef7b066f4c99462ba14fb3f9dd0f107a
Autor:
Tej H. Patel, Lucas Norman, Steven Chang, Sina Abedi, Catherine Liu, Marilyn Chwa, Shari R. Atilano, Kunal Thaker, Stephanie Lu, S. Michal Jazwinski, Michael V. Miceli, Nitin Udar, Daniela Bota, M. Cristina Kenney
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Background: Cisplatin, a powerful antitumor agent, causes formation of DNA adducts, and activation of apoptotic pathways. Presently, cisplatin resistance develops in up to 70% of patients but the underlying molecular mechanism(s) are unclear and ther
Externí odkaz:
https://doaj.org/article/5ec2b421a256417c8358fc231cbeb719
Autor:
Kunal Thaker, Marilyn Chwa, Shari R. Atilano, Pinar Coskun, Javier Cáceres-del-Carpio, Nitin Udar, David S. Boyer, S. Michal Jazwinski, Michael V. Miceli, Anthony B. Nesburn, Baruch D. Kuppermann, M. Cristina Kenney
Publikováno v:
Neurobiology of Disease, Vol 93, Iss , Pp 64-77 (2016)
Mitochondrial (mt) DNA haplogroups, defined by specific single nucleotide polymorphism (SNP) patterns, represent populations of diverse geographic origins and have been associated with increased risk or protection of many diseases. The H haplogroup i
Externí odkaz:
https://doaj.org/article/d6e560fb3fc94d71b46c7c8d58cb7872
Autor:
Deepika Malik, Tiffany Hsu, Payam Falatoonzadeh, Javier Cáceres-del-Carpio, Mohamed Tarek, Marilyn Chwa, Shari R Atilano, Claudio Ramirez, Anthony B Nesburn, David S Boyer, Baruch D Kuppermann, S Michal Jazwinski, Michael V Miceli, Douglas C Wallace, Nitin Udar, M Cristina Kenney
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e99003 (2014)
It has been recognized that cells do not respond equally to ultraviolet (UV) radiation but it is not clear whether this is due to genetic, biochemical or structural differences of the cells. We have a novel cybrid (cytoplasmic hybrids) model that all
Externí odkaz:
https://doaj.org/article/9f2ccfb6cc0d49d39cf771ce7acbda7a
Autor:
M Cristina Kenney, Marilyn Chwa, Shari R Atilano, Janelle M Pavlis, Payam Falatoonzadeh, Claudio Ramirez, Deepika Malik, Tiffany Hsu, Grace Woo, Kyaw Soe, Anthony B Nesburn, David S Boyer, Baruch D Kuppermann, S Michal Jazwinski, Michael V Miceli, Douglas C Wallace, Nitin Udar
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54339 (2013)
Mitochondrial dysfunction is associated with the development and progression of age-related macular degeneration (AMD). Recent studies using populations from the United States and Australia have demonstrated that AMD is associated with mitochondrial
Externí odkaz:
https://doaj.org/article/1e6297845c0d4c1bbfd598fd15860ca7
Publikováno v:
BioTechniques, Vol 21, Iss 6, Pp 1036-1038 (1996)
Externí odkaz:
https://doaj.org/article/bd65e455143244fc99db57dad60920a5