Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Nitin K, Gopaul"'
Publikováno v:
Diabetes Care. 25:537-541
OBJECTIVES—Acute hyperglycemia in type 2 diabetes increases the generation of plasma 8-epi-prostaglandin F2 (8-epi-PGF2α) isoprostane, a sensitive direct marker of in vivo free radical oxidative damage to membrane phospholipids. RESEARCH DESIGN AN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ef55e064a8d0879f089f64ed9f9d00f
https://doi.org/10.2337/diacare.25.3.537
https://doi.org/10.2337/diacare.25.3.537
Publikováno v:
British Journal of Pharmacology. 125:895-901
1. We examined the relationship between oxidant stress and the vasodepressor activity of glyceryl trinitrate (GTN) in vivo, including rapid GTN tolerance development, in 13-week old obese and age-matched lean Zucker rats which had been maintained for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17ae63cfaa6db2d93106f7a2527e1f16
https://doi.org/10.1038/sj.bjp.0702132
https://doi.org/10.1038/sj.bjp.0702132
Publikováno v:
Biochemical and Biophysical Research Communications. 200:338-343
It has been recently reported that a series of prostaglandin F2-like compounds (PGF2-isoprostanes) are produced in vivo by non-enzymatic peroxidation of arachidonic acid. Of these, 8-epi-PGF2 alpha is the major component and has been shown to be a po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::015b37df91f89c5bd5f668223073cae4
https://doi.org/10.1006/bbrc.1994.1453
https://doi.org/10.1006/bbrc.1994.1453
Autor:
Nitin K, Gopaul, Erik E, Anggård
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 225
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9cd20160710ac82367efa13b92eac7e4
https://pubmed.ncbi.nlm.nih.gov/12769500
https://pubmed.ncbi.nlm.nih.gov/12769500
Publikováno v:
Free radical biologymedicine. 28(5)
Measurement of the F(2)-isoprostane, 8-epi-PGF(2alpha) is increasingly used as a sensitive and reliable marker of lipid peroxidation in vivo. Because the majority of 8-epi-PGF(2alpha) in plasma is associated with lipoproteins, it is possible that 8-e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53d42297667a293e863b2fbe4b9202c7
https://pubmed.ncbi.nlm.nih.gov/10754277
https://pubmed.ncbi.nlm.nih.gov/10754277
Publikováno v:
European journal of pharmacology. 377(1)
We have concurrently investigated oxidant stress, glucose tolerance and glucose-stimulated insulin responses in the obese Zucker rat, a widely used model of insulin resistance. The plasma level of the lipid peroxidation product 8-epi-prostaglandin F2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b9cfc5743eb74b49357cfe753325962
https://pubmed.ncbi.nlm.nih.gov/10448931
https://pubmed.ncbi.nlm.nih.gov/10448931
Autor:
Erik Änggård, A.I. Mallet, D. J. Betteridge, Simon P. Wolff, Jaffar Nourooz-Zadeh, Nitin K Gopaul
Publikováno v:
FEBS letters. 368(2)
This study reports plasma levels of a specific nonenzymatic peroxidation product of arachidonic acid, esterified 8-epi-PGF2 alpha, from healthy- and NIDDM individuals as an index of oxidative stress in vivo. Plasma 8-epi-PGF2 alpha was isolated by so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05301faebc48bb923f08b56a0f96e147
https://pubmed.ncbi.nlm.nih.gov/7628610
https://pubmed.ncbi.nlm.nih.gov/7628610
Publikováno v:
Journal of chromatography. B, Biomedical applications. 667(2)
Recently, it has been reported that a series of prostaglandin F2-like compounds (F2-isoprostanes) are produced in vivo during peroxidation of arachidonic acid by a mechanism independent of the cyclooxygenase pathway. Of these, 8-epi-PGF2 alpha is sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::836c25a31249bbf1f77ba638209d2fbc
https://pubmed.ncbi.nlm.nih.gov/7663692
https://pubmed.ncbi.nlm.nih.gov/7663692
Publikováno v:
FEBS letters. 348(3)
We investigated the formation of F2-isoprostanes produced by non-enzymatic peroxidation of arachidonic acid during rabbit aortic endothelial cell-mediated oxidation of low density lipoprotein (LDL). Free and total (sum of free and esterified) levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24952f35a0c35de06a9e51c5721bea3f
https://pubmed.ncbi.nlm.nih.gov/8034058
https://pubmed.ncbi.nlm.nih.gov/8034058