Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Nitin J Karandikar"'
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0285166 (2023)
CD4+ T-helper 17 (Th17) T cells are a key population in protective immunity during infection and in self-tolerance/autoimmunity. Through the secretion of IL-17, Th17 cells act in promotion of inflammation and are thus a major potential therapeutic ta
Externí odkaz:
https://doaj.org/article/333a9ae402f544698131cda2f043e023
Autor:
Sushmita Sinha, Pranav S Renavikar, Michael P Crawford, Scott M Steward-Tharp, Ashley Brate, Eva Tsalikian, Michael Tansey, Ezzatollah T Shivapour, Tracey Cho, John Kamholz, Nitin J Karandikar
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0238070 (2020)
Factors regulating self-antigen directed immune-responses in autoimmunity are poorly understood. Signal regulatory protein gamma (SIRPγ) is a human T-cell specific protein with genetic variants associated with type 1 diabetes (T1D). SIRPγ's functio
Externí odkaz:
https://doaj.org/article/1e55512d7b8a45a5a6a12f43ec8393a6
Autor:
Matthew Cummings, Anitha Christy Sigamani Arumanayagam, Picheng Zhao, Sunil Kannanganat, Olaf Stuve, Nitin J Karandikar, Todd N Eagar
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0200752 (2018)
Multiple Sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) where pathology is thought to be regulated by autoreactive T cells of the Th1 and Th17 phenotype. In this study we sought to understand the functions
Externí odkaz:
https://doaj.org/article/4c5efb23b28143f8bc4ff7b0d8befb17
Autor:
John Larry Blau, Joseph D Wilford, Susan K Dane, Nitin J Karandikar, Emily S Fuller, Debbie J Jacobsmeier, Melissa A Jans, Elisabeth A Horning, Matthew D Krasowski, Bradley A Ford, Kent R Becker, Jeanine M Beranek, Robert A Robinson
Publikováno v:
Journal of Pathology Informatics, Vol 8, Iss 1, Pp 47-47 (2017)
Background: Beaker is a relatively new laboratory information system (LIS) offered by Epic Systems Corporation as part of its suite of health-care software and bundled with its electronic medical record, EpicCare. It is divided into two modules, Beak
Externí odkaz:
https://doaj.org/article/1823ad8a4c9f4be28585d21c6da4e2d9
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105763 (2014)
Experimental autoimmune encephalomyelitis (EAE) is a well-established murine model of multiple sclerosis, an immune-mediated demyelinating disorder of the central nervous system (CNS). We have previously shown that CNS-specific CD8+ T cells (CNS-CD8+
Externí odkaz:
https://doaj.org/article/6e333742a58444628edce7e6c8f4292b
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66772 (2013)
The exact mechanism of glatiramer acetate (GA, Copaxone®), an FDA-approved immunomodulatory therapy for multiple sclerosis (MS), remains unclear after decades of research. Previously, we have shown that GA therapy of MS induces CD8(+) T cell respons
Externí odkaz:
https://doaj.org/article/a1fe190c1f2e47a78d5f41c1aadaf85e
Autor:
Matthew D Krasowski, Joseph D Wilford, Wanita Howard, Susan K Dane, Scott R Davis, Nitin J Karandikar, John L Blau, Bradley A Ford
Publikováno v:
Journal of Pathology Informatics, Vol 7, Iss 1, Pp 7-7 (2016)
Background: Epic Beaker Clinical Pathology (CP) is a relatively new laboratory information system (LIS) operating within the Epic suite of software applications. To date, there have not been any publications describing implementation of Beaker CP. In
Externí odkaz:
https://doaj.org/article/04856c7d9a20475897e2eebaa6e2e6ca
Autor:
Mudassir Farooqui, Santiago Ortega‐Gutierrez, Katherine Hernandez, Vanessa O. Torres, Andres Dajles, Cynthia B. Zevallos, Darko Quispe‐Orozco, Alan Mendez‐Ruiz, Kenneth Manzel, Patrick Ten Eyck, Daniel Tranel, Nitin J. Karandikar, Sterling B. Ortega
Publikováno v:
Annals of clinical and translational neurologyREFERENCES.
Despite successful endovascular therapy, a proportion of stroke patients exhibit long-term functional decline, regardless of the cortical reperfusion. Our objective was to evaluate the early activation of the adaptive immune response and its impact o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd9a8df2ff795351eb7f8ec9c128ec1e
https://pubmed.ncbi.nlm.nih.gov/36579400
https://pubmed.ncbi.nlm.nih.gov/36579400
Autor:
Isaac J. Jensen, Vladimir P. Badovinac, Nitin J. Karandikar, Ashley A. Brate, Alexander W. Boyden
Publikováno v:
The Journal of Immunology. 206:1151-1160
Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the CNS. We have previously demonstrated that CNS-specific CD8 T cells possess a disease-suppressive function in MS and variations of its animal model, experimental autoimmune enc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b94ef81fd455c59b302b2cddadbf5df
https://doi.org/10.4049/jimmunol.2001143
https://doi.org/10.4049/jimmunol.2001143
Autor:
Carol J. Holman, Nitin J. Karandikar, Timothy Dunham, Saurav Chopra, Sergei Syrbu, Benjamin W. Darbro
Publikováno v:
American Journal of Clinical Pathology. 156:198-204
Objectives We sought to investigate the clinical utility of flow cytometry (FC) and fluorescence in situ hybridization (FISH) in the workup of myeloma. Methods We retrospectively reviewed the reports of bone marrow biopsies received for myeloma evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73127f7d28c4821c73014b6ba6e34b85
https://doi.org/10.1093/ajcp/aqaa224
https://doi.org/10.1093/ajcp/aqaa224