Výsledky vyhledávání - "Nitin C. Salvi"

Akademický článek

Supplementation of polyclonal antibodies, developed against epitope-string toxin-specific peptide immunogens, to commercial polyvalent antivenom, shows improved neutralization of Indian Big Four and Naja kaouthia snake venoms

Autor: Abhishek Chanda, Nitin C. Salvi, Pravin V. Shelke, Bhargab Kalita, Aparup Patra, Upasana Puzari, Milind V. Khadilkar, Ashis K. Mukherjee

Publikováno v: Toxicon: X, Vol 24, Iss , Pp 100210- (2024)

Snakebites profoundly impact the rural population of tropical nations, leading to significant socio-economic repercussions. Polyvalent antivenom (PAV) therapy faces several limitations, including intra-specific variations and poor efficacy against so

Externí odkaz: https://doaj.org/article/ea4f5258629d4cda97db58350ef3a7b7

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Akademický článek

Assessment of quality and pre-clinical efficacy of a newly developed polyvalent antivenom against the medically important snakes of Sri Lanka

Autor: Aparup Patra, Bhargab Kalita, Milind V. Khadilkar, Nitin C. Salvi, Pravin V. Shelke, Ashis K. Mukherjee

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)

Abstract Snake envenomation is a severe problem in Sri Lanka (SL) and Indian polyvalent antivenom (PAV) is mostly used for treating snakebite albeit due to geographical variation in venom composition, Indian PAV shows poor efficacy in neutralizing th

Externí odkaz: https://doaj.org/article/725e566ca49f47b3881f135a01a47c6e

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Assessment of quality and pre-clinical efficacy of a newly developed polyvalent antivenom against the medically important snakes of Sri Lanka

Autor: Nitin C. Salvi, Aparup Patra, Pravin V. Shelke, M.V. Khadilkar, Ashis K. Mukherjee, Bhargab Kalita

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Scientific Reports

Snake envenomation is a severe problem in Sri Lanka (SL) and Indian polyvalent antivenom (PAV) is mostly used for treating snakebite albeit due to geographical variation in venom composition, Indian PAV shows poor efficacy in neutralizing the lethali

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a95fd88fc741bf573ea5791958183f
https://doi.org/10.1038/s41598-021-97501-2

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Evaluation of health status of horses immunized with snake venom and montanide adjuvants, IMS 3012 (nanoparticle), ISA 206 and ISA 35 (emulsion based) during polyvalent snake antivenom production: Hematological and biochemical assessment

Autor: P.A. Shenoy, Nitin C. Salvi, J.M. Sonpetkar, R.L. Deopurkar, A.B. Waghmare

Publikováno v: Toxicon. 82:83-92

Several biochemical and hematological changes in horses are observed during production of snake antivenom. Although conventional adjuvants like Freund's (Complete and Incomplete) are good immunopotentiators, they produce considerable local reactions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f96712cadfd355b3a3b1b9ef1b684f6
https://doi.org/10.1016/j.toxicon.2014.02.012

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Corrigendum to 'Rapid and selective detection of experimental snake envenomation - Use of gold nanoparticle based lateral flow assay' [Toxicon 119 (2016) 299-306]

Autor: Nitin C. Salvi, Innus K. Shaikh, Abhilasha S. Pawade, Mugdha Potnis-Lele, Vishal B. Wagh, Nitin D. Jadhav, Indrasen G. Waykar, Balasaheb S. Pawade, A.B. Waghmare

Publikováno v: Toxicon : official journal of the International Society on Toxinology. 125

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c8d217f988bed68a78884b5fe47ef39
https://pubmed.ncbi.nlm.nih.gov/27377230

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Rapid and selective detection of experimental snake envenomation - Use of gold nanoparticle based lateral flow assay

Autor: Balasaheb S. Pawade, Innus K. Shaikh, A.B. Waghmare, Abhilasha S. Pawade, Nitin C. Salvi, Mugdha Potnis-Lele, Nitin D. Jadhav, Indrasen G. Waykar, Vishal B. Wagh

Publikováno v: Toxicon : official journal of the International Society on Toxinology. 119

In this study, we have developed a gold nanoparticle based simple, rapid lateral flow assay (LFA) for detection of Indian Cobra venom (CV) and Russell's viper venom (RV). Presently, there is no rapid, reliable, and field diagnostic test available in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be94da6bfcae5210622f3e44f60cbf16
https://pubmed.ncbi.nlm.nih.gov/27951506

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Validation of Indirect ELISA for Quantitative Testing of Rabies Antibodies During Production of Antirabies Serum using Equines

Autor: M.V. Khadilkar, S.K. Gade, R.L. Deopurkar, L.S. Mohite, Nitin C. Salvi, A.B. Waghmare, M.Y. Kalolikar

Publikováno v: Procedia in Vaccinology. 2(1):3-11

Rabies is still a cause of global concern, particularly in the developing countries. The treatment for post exposure prophylaxis is a combination of administration of vaccine and specific antiserum. Although equine antirabies immunoglobulin is availa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc360b644a8cf17084cc7ae094875878

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Comparison of Montanide adjuvants, IMS 3012 (Nanoparticle), ISA 206 and ISA 35 (Emulsion based) alongwith incomplete Freund's adjuvant for hyperimmunization of equines used for production of polyvalent snake antivenom

Autor: R.L. Deopurkar, M.V. Khadilkar, Milind Kalolikar, A.B. Waghmare, S.K. Gade, Nitin C. Salvi

Publikováno v: Vaccine. 27:1067-1072

The use of adjuvant is of fundamental importance in vaccines formulations and antisera production. Currently selection and use of adjuvant systems in snake antivenom preparation has become a major issue in terms of animal welfare as well as economics

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca6a8f7186983edf02824eb40cc09ff4
https://doi.org/10.1016/j.vaccine.2008.11.103

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