Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Nitin Hingankar"'
Autor:
Ranajoy Mullick, Jyoti Sutar, Nitin Hingankar, Suprit Deshpande, Madhuri Thakar, Seema Sahay, Rajesh P. Ringe, Sampurna Mukhopadhyay, Ajit Patil, Shubhangi Bichare, Kailapuri G. Murugavel, Aylur K. Srikrishnan, Rajat Goyal, Devin Sok, Jayanta Bhattacharya
Publikováno v:
Retrovirology, Vol 18, Iss 1, Pp 1-13 (2021)
Abstract Background The potential use of the broadly neutralizing monoclonal antibodies (bnAbs) towards prophylaxis and treatment to HIV-1 is currently being explored. While a number of promising bnAbs have been discovered and a few of them have prog
Externí odkaz:
https://doaj.org/article/99653c24e0ee4fc79b2ce85aad8fba26
Autor:
Nitin Hingankar, Suprit Deshpande, Payel Das, Zaigham Abbas Rizvi, Constantinos Kurt Wibmer, Poppy Mashilo, Mohammed Yousuf Ansari, Alison Burns, Shawn Barman, Fangzhu Zhao, Sohini Mukherjee, Jonathan L Torres, Souvick Chattopadhyay, Farha Mehdi, Jyoti Sutar, Deepak Kumar Rathore, Kamal Pargai, Janmejay Singh, Sudipta Sonar, Kamini Jakhar, Jyotsna Dandotiya, Sankar Bhattacharyya, Shailendra Mani, Sweety Samal, Savita Singh, Pallavi Kshetrapal, Ramachandran Thiruvengadam, Gaurav Batra, Guruprasad Medigeshi, Andrew B Ward, Shinjini Bhatnagar, Amit Awasthi, Devin Sok, Jayanta Bhattacharya
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4, p e1010465 (2022)
Although efficacious vaccines have significantly reduced the morbidity and mortality of COVID-19, there remains an unmet medical need for treatment options, which monoclonal antibodies (mAbs) can potentially fill. This unmet need is exacerbated by th
Externí odkaz:
https://doaj.org/article/a5a76225c38141629fe49e262e9a20b8
Autor:
Rajesh Kumar, Suprit Deshpande, Leigh M Sewall, Gabriel Ozorowski, Christopher A Cottrell, Wen-Hsin Lee, Lauren G Holden, Sara T Richey, Antra Singh Chandrawacar, Kanika Dhiman, Ashish, Vivek Kumar, Shubbir Ahmed, Nitin Hingankar, Naresh Kumar, Kailapuri G Murugavel, Aylur K Srikrishnan, Devin Sok, Andrew B Ward, Jayanta Bhattacharya
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1008977 (2021)
Evaluating the structure-function relationship of viral envelope (Env) evolution and the development of broadly cross-neutralizing antibodies (bnAbs) in natural infection can inform rational immunogen design. In the present study, we examined the mag
Externí odkaz:
https://doaj.org/article/5c0bde4098d240bfabd6e084c96ccc53
Autor:
Jyoti Sutar, Suprit Deshpande, Ranajoy Mullick, Nitin Hingankar, Vainav Patel, Jayanta Bhattacharya
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251969 (2021)
Evolving diversity in globally circulating HIV-1 subtypes presents a formidable challenge in defining and developing neutralizing antibodies for prevention and treatment. HIV-1 subtype C is responsible for majority of global HIV-1 infections. In the
Externí odkaz:
https://doaj.org/article/aba15ec568594f3c91593efd058b2219
Autor:
Srabanti Rakshit, Nitin Hingankar, Shuba Varshini Alampalli, Vasista Adiga, Bharath K. Sundararaj, Pravat Nalini Sahoo, Greg Finak, Anto Jesuraj Uday Kumar J, Chirag Dhar, George D’Souza, Rashmi Govind Virkar, Manisha Ghate, Madhuri R. Thakar, Ramesh S. Paranjape, Stephen C. De Rosa, Tom H.M. Ottenhoff, Annapurna Vyakarnam
Publikováno v:
Cell Reports, Vol 33, Iss 9, Pp 108451- (2020)
Summary: HIV infection predisposes latent tuberculosis-infected (LTBI) subjects to active TB. This study is designed to determine whether HIV infection of LTBI subjects compromises the balanced Mycobacterium tuberculosis (Mtb)-specific T helper 17 (T
Externí odkaz:
https://doaj.org/article/81a63bfce56344609c4df45cb0d72869
Autor:
Suprit Deshpande, Mohammed Yousuf Ansari, Jyoti Sutar, Payel Das, Nitin Hingankar, Sohini Mukherjee, Priyanka Jayal, Savita Singh, Anbalagan Anantharaj, Janmejay Singh, Souvick Chattopadhyay, Sreevatsan Raghavan, Mudita Gosain, Supriya Chauhan, Shweta Shrivas, Chaman Prasad, Sangeeta Chauhan, Neha Sharma, Pradipta Jana, Ramachandran Thiruvengadam, Pallavi Kshetrapal, Nitya Wadhwa, Bhabatosh Das, Gaurav Batra, Guruprasad Medigeshi, Devin Sok, Shinjini Bhatnagar, Pramod Kumar Garg, Jayanta Bhattacharya
Publikováno v:
Microbiology Spectrum. 11
Understanding the quality of immune repertoire triggered during natural infection can provide vital clues that form the basis for development of humoral immune response in some individuals capable of broadly neutralizing pan SARS-CoV-2 variants. We a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6788daa298a7e47b506c9b11ce563032
https://doi.org/10.1128/spectrum.04332-22
https://doi.org/10.1128/spectrum.04332-22
Autor:
Clayton Fernando Rencilin, Mohammad Yousuf Ansari, Arnab Chatterjee, Suprit Deshpande, Sohini Mukherjee, Randhir Singh, Sowrabha Jayatheertha, Poorvi M. Reddy, Payel Das, Nitin Hingankar, Deepak Rathore, Raghavan Varadarajan, Jayanta Bhattacharya, Somnath Dutta
While vaccines have by large been found to effective against the evolving SARS-CoV-2 variants, the profound and rapid effectivity of monoclonal antibodies (mAbs) in significantly reducing hospitalization to severe disease outcomes have also been demo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25811862babb367c31dd2baddb3ac5e4
https://doi.org/10.1101/2022.12.03.518949
https://doi.org/10.1101/2022.12.03.518949
Autor:
Nitin Hingankar, Suprit Deshpande, Payel Das, Zaigham Abbas Rizvi, Alison Burns, Shawn Barman, Fangzhu Zhao, Mohammed Yousuf Ansari, Sohini Mukherjee, Jonathan L. Torres, Souvick Chattopadhyay, Farha Mehdi, Jyoti Sutar, Deepak Kumar Rathore, Kamal Pargai, Janmejay Singh, Sudipta Sonar, Kamini Jakhar, Sankar Bhattacharyya, Shailendra Mani, Savita Singh, Jyotsna Dandotiya, Pallavi Kshetrapal, Ramachandran Thiruvengadam, Gaurav Batra, Guruprasad R Medigeshi, Andrew Ward, Shinjini Bhatnagar, Amit Awasthi, Devin Sok, Jayanta Bhattacharya
Although efficacious vaccines have significantly reduced the morbidity and mortality due to COVID-19, there remains an unmet medical need for treatment options, which monoclonal antibodies (mAbs) can potentially fill. This unmet need is exacerbated b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::450862064ab351ccd4727e3e274fb0c3
https://doi.org/10.1101/2021.12.25.474152
https://doi.org/10.1101/2021.12.25.474152
Autor:
Ranajoy Mullick, Sutar, Jyoti, Nitin Hingankar, Suprit Deshpande, Thakar, Madhuri, Sahay, Seema, Ringe, Rajesh P., Sampurna Mukhopadhyay, Patil, Ajit, Shubhangi Bichare, Kailapuri G. Murugavel, Aylur K. Srikrishnan, Rajat Goyal, Sok, Devin, Bhattacharya, Jayanta
Additional file 1: Table S1. History of year of collection of clinical samples, disease stages and env genetic properties.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e08e0f96e2159fe3c1bb79179ae528a
Autor:
Ranajoy Mullick, Sutar, Jyoti, Nitin Hingankar, Suprit Deshpande, Thakar, Madhuri, Sahay, Seema, Ringe, Rajesh P., Sampurna Mukhopadhyay, Patil, Ajit, Shubhangi Bichare, Kailapuri G. Murugavel, Aylur K. Srikrishnan, Rajat Goyal, Sok, Devin, Bhattacharya, Jayanta
Additional file 2: Table S2. Mapping key amino acid substitutions associated with resistance to the bnAbs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2918ffdd8ea3717d8a763d29768e2f19