Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nithya A. Fernandopulle"'
Autor:
Lin Hsin, Nithya A. Fernandopulle, Jie Ding, Chris Lumb, Nicholas Veldhuis, John A. Karas, Susan E. Northfield, Graham A. Mackay
Publikováno v:
Pharmacology Research & Perspectives, Vol 10, Iss 4, Pp n/a-n/a (2022)
Abstract The tachykinin neuropeptide substance P (SP) is the canonical agonist peptide for the neurokinin 1 receptor (NK1R). More recently, it has also been shown to activate the Mas‐related G protein‐coupled receptor X2 (MRGPRX2) receptor on mas
Externí odkaz:
https://doaj.org/article/cfb20b206d1349c798868224e851ca6a
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Acute anaphylaxis to small molecule drugs is largely considered to be antibody-mediated with immunogloblin E (IgE) and mast cell activation being key. More recently, a role for drug-reactive immunoglobulin G (IgG) with neutrophil activation has also
Externí odkaz:
https://doaj.org/article/902754596de042d29c3d9292309981a4
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical ImmunologyREFERENCES. 51(5)
Background Neuromuscular blocking agents (NMBAs) can cause both IgE-dependent and independent anaphylactic reactions, with activation of the mast cell receptor MRGPRX2 being important to the latter. Sugammadex, a reversal agent for certain aminostero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b63e4ba78a40d8d4fca89474af55124e
https://pubmed.ncbi.nlm.nih.gov/33548115
https://pubmed.ncbi.nlm.nih.gov/33548115
Publikováno v:
Clinical & Experimental Allergy. 51:978-979
We thank Elst and colleagues for their commentary on our recently published article in this journal, which facilitates greater discussion on the topic. We agree that, although strongly suggested by pre-clinical studies, direct evidence for MRGPRX2 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddee5d3febba02ad40e33ca82ccc4810
https://doi.org/10.1111/cea.13844
https://doi.org/10.1111/cea.13844