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A Drosophila model relevant to chemotherapy-related cognitive impairment.

Autor: Torre, Matthew, Bukhari, Hassan, Nithianandam, Vanitha, Zanella, Camila A., Mata, Douglas A., Feany, Mel B.

Publikováno v: Scientific Reports; 11/7/2023, Vol. 13 Issue 1, p1-11, 11p

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Transcriptional programs mediating neuronal toxicity and altered glial-neuronal signaling in a Drosophila knock-in tauopathy model.

Autor: Bukhari H; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland 20815, USA., Nithianandam V; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland 20815, USA., Battaglia RA; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland 20815, USA., Cicalo A; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland 20815, USA.; Genomics and Bioinformatics Hub, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA., Sarkar S; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA., Comjean A; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts 02115, USA., Hu Y; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts 02115, USA., Leventhal MJ; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.; MIT Ph.D. Program in Computational and Systems Biology, Cambridge, Massachusetts 02139, USA., Dong X; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland 20815, USA.; Genomics and Bioinformatics Hub, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA., Feany MB; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA; mel_feany@hms.harvard.edu.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland 20815, USA.

Publikováno v: Genome research [Genome Res] 2024 May 15; Vol. 34 (4), pp. 590-605. Date of Electronic Publication: 2024 May 15.