Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Nithi Asavapanumas"'
Autor:
Keatdamrong Janpipatkul, Nareerat Sutjarit, Amornrat Tangprasittipap, Tai Chaiamarit, Pawarit Innachai, Kanoknetr Suksen, Tanida Chokpanuwat, Thipwimol Tim-Aroon, Usanarat Anurathapan, Natee Jearawiriyapaisarn, Alisa Tubsuwan, Supareak Bowornpinyo, Nithi Asavapanumas, Arthit Chairoungdua, Kanit Bhukhai, Suradej Hongeng
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-14 (2024)
Abstract Background Gaucher disease (GD) is one of the most common types of lysosomal storage diseases (LSDs) caused by pathogenic variants of lysosomal β-glucocerebrosidase gene (GBA1), resulting in the impairment of Glucocerebrosidase (GCase) enzy
Externí odkaz:
https://doaj.org/article/59a850ee25e242c784be1f2144fdcbd3
Autor:
Phongthon Kanjanasirirat, Witchuda Saengsawang, Pimonrat Ketsawatsomkron, Nithi Asavapanumas, Suparerk Borwornpinyo, Sunhapas Soodvilai, Suradej Hongeng, Sitthivut Charoensutthivarakul
Publikováno v:
Heliyon, Vol 10, Iss 20, Pp e39343- (2024)
Blood-brain barrier (BBB) is a crucial membrane safeguarding neural tissue by controlling the molecular exchange between blood and the brain. However, assessing BBB permeability presents challenges for central nervous system (CNS) drug development. I
Externí odkaz:
https://doaj.org/article/b1084fd222ea4a389b0741271da328ba
Autor:
Tanapat Pornsukjantra, Nongluk Saikachain, Nareerat Sutjarit, Arthaporn Khongkrapan, Alisa Tubsuwan, Kanit Bhukhai, Thipwimol Tim-Aroon, Usanarat Anurathapan, Suradej Hongeng, Nithi Asavapanumas
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Gaucher disease (GD) is a lysosomal storage disorder caused by a mutation in the GBA1 gene, responsible for encoding the enzyme Glucocerebrosidase (GCase). Although neuronal death and neuroinflammation have been observed in the brains of ind
Externí odkaz:
https://doaj.org/article/0f6e96ed824b4ccca62b25c09c125f40
Autor:
Kitsada Kangboonruang, Tanapat Pornsukjantra, Pirut Tong-Ngam, Tanida Chokpanuwat, Thipwimol Tim-Aroon, Duangrurdee Wattanasirichaigoon, Usanarat Anurathapan, Suradej Hongeng, Nithi Asavapanumas, Kanit Bhukhai, Alisa Tubsuwan
Publikováno v:
Stem Cell Research, Vol 73, Iss , Pp 103229- (2023)
Gaucher disease (GD) is a common lysosomal storage disease resulting from mutations in the glucocerebrosidase (GBA1) gene. This genetic disorder manifests with symptoms affecting multiple organs, yet the underlying mechanisms leading to pathology rem
Externí odkaz:
https://doaj.org/article/7d6440b83bd94cfe949e746889387da2
Publikováno v:
Biomedicines, Vol 11, Iss 4, p 1011 (2023)
Mitochondria-associated membranes (MAMs) regulate several cellular processes, including calcium homeostasis and mitochondrial function, and dynamics. While MAMs are upregulated in Alzheimer’s disease (AD), the mechanisms underlying this increase re
Externí odkaz:
https://doaj.org/article/c06132f3ca3e4e59af7a8ed71cbcbc54
Autor:
Tanapat Pornsukjantra, Kitsada Kangboonruang, Pirut Tong-Ngam, Thipwimol Tim-Aroon, Duangrurdee Wattanasirichaigoon, Usanarat Anurathapan, Suradej Hongeng, Alisa Tubsuwan, Kanit Bhukhai, Nithi Asavapanumas
Publikováno v:
Stem Cell Research, Vol 60, Iss , Pp 102698- (2022)
Gaucher disease (GD) is one of the most prevalent lysosomal storage diseases caused by mutation of glucocerebrosidase (GBA1) gene. GD patients develop symptoms in various organs of the body; however, the underlying mechanisms causing pathology are st
Externí odkaz:
https://doaj.org/article/473a8ab9e4dd4d03953ac06bf76f6fbd
Publikováno v:
Neurobiology of Disease, Vol 121, Iss , Pp 315-326 (2019)
Besides deficits in memory and cognition, impaired visual processing is common for Alzheimer's disease (AD) patients and mouse models of AD but underlying mechanisms still remain unclear. Using in vivo Ca2+ imaging of the mouse primary visual cortex
Externí odkaz:
https://doaj.org/article/c3ff986c53454773a4dac4946adba7a6
Autor:
Lusine Danielyan, Matthias Schwab, Georg Siegel, Bianca Brawek, Olga Garaschuk, Nithi Asavapanumas, Marine Buadze, Ali Lourhmati, Hans-Peter Wendel, Meltem Avci-Adali, Marcel A. Krueger, Carsten Calaminus, Ulrike Naumann, Stefan Winter, Elke Schaeffeler, Annett Spogis, Sandra Beer-Hammer, Jonas J. Neher, Gabriele Spohn, Anja Kretschmer, Eva-Maria Krämer-Albers, Kerstin Barth, Hong Jun Lee, Seung U. Kim, William H. Frey, II, Claus D. Claussen, Dirk M. Hermann, Thorsten R. Doeppner, Erhard Seifried, Christoph H. Gleiter, Hinnak Northoff, Richard Schäfer
Publikováno v:
EBioMedicine, Vol 60, Iss , Pp 102989- (2020)
Background: Stem cells` (SC) functional heterogeneity and its poorly understood aetiology impedes clinical development of cell-based therapies in regenerative medicine and oncology. Recent studies suggest a strong correlation between the SC migration
Externí odkaz:
https://doaj.org/article/50fadaeaeb26482dbe9ab2d00b7b2fef
Autor:
Natini Jinawath, Sacarin Bunbanjerdsuk, Maneerat Chayanupatkul, Nuttapong Ngamphaiboon, Nithi Asavapanumas, Jisnuson Svasti, Varodom Charoensawan
Publikováno v:
Journal of Translational Medicine, Vol 14, Iss 1, Pp 1-13 (2016)
Abstract With the wealth of data accumulated from completely sequenced genomes and other high-throughput experiments, global studies of biological systems, by simultaneously investigating multiple biological entities (e.g. genes, transcripts, protein
Externí odkaz:
https://doaj.org/article/b8f7b32a1aa14e9ba553a763213895a3
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106824 (2014)
Neuromyelitis optica (NMO) is an autoimmune demyelinating disease of the central nervous system in which binding of anti-aquaporin-4 (AQP4) autoantibodies (NMO-IgG) to astrocytes causes complement-dependent cytotoxicity (CDC) and inflammation resulti
Externí odkaz:
https://doaj.org/article/83f3d25240314191980d6571390a9f9d