Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Nita R. Shah"'
Autor:
Nita R. Shah, Tomas B. Voisin, Edward S. Parsons, Courtney M. Boyd, Bart W. Hoogenboom, Doryen Bubeck
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Cholesterol-dependent cytolysins (CDCs) are bacterial pore-forming virulence factors. Cryo-EM structure of an early conformation of the CDC ILY from Streptococcus intermedius, bound to the human immune receptor CD59, provides insight into ILY oligome
Externí odkaz:
https://doaj.org/article/bad042a16128475abd06082cd212d8e7
Publikováno v:
AIMS Biophysics, Vol 3, Iss 1, Pp 171-194 (2016)
Membrane-integral pyrophosphatases (mPPases) are found in several human pathogens, including Plasmodium species, the protozoan parasites that cause malaria. These enzymes hydrolyze pyrophosphate and couple this to the pumping of ions (H+ and/or Na+)
Externí odkaz:
https://doaj.org/article/6f96bafa07cd42bbb233f40f5a021ee2
Autor:
Nita R. Shah, Craig Wilkinson, Steven P. D. Harborne, Ainoleena Turku, Kun-Mou Li, Yuh-Ju Sun, Sarah Harris, Adrian Goldman
Publikováno v:
Structural Dynamics, Vol 4, Iss 3, Pp 032105-032105-12 (2017)
Membrane-integral pyrophosphatases (mPPases) couple the hydrolysis of pyrophosphate (PPi) to the pumping of Na+, H+, or both these ions across a membrane. Recently solved structures of the Na+-pumping Thermotoga maritima mPPase (TmPPase) and H+-pumpi
Externí odkaz:
https://doaj.org/article/317fe7dc8b6547d3aeee4f1e62d4d008
Autor:
Charles A. R. Cotton, Doryen Bubeck, Burak V. Kabasakal, Blanca Echeverria, Ciaran McFarlane, James W. Murray, Nita R. Shah
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The Calvin–Benson (CB) cycle in plants, algae, and cyanobacteria fixes most of the carbon in most of the biomass on Earth. The CB cycle is regulated by the redox state, which enables it to be turned off in the dark. One part of this re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4047492bfec333c0cc89b2e6f18c78fa
https://doi.org/10.1073/pnas.1906722116
https://doi.org/10.1073/pnas.1906722116
Autor:
Courtney M. Boyd, Tomas B. Voisin, Nita R. Shah, Bart W. Hoogenboom, Edward S. Parsons, Doryen Bubeck
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Cholesterol-dependent cytolysins (CDCs) are pore-forming proteins that serve as major virulence factors for pathogenic bacteria. They target eukaryotic cells using different mechanisms, but all require the presence of cholesterol to pierce lipid bila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab7e3ee7b3a761a39ad3a408771ed86
https://doi.org/10.1101/2020.06.16.154724
https://doi.org/10.1101/2020.06.16.154724
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20585 (2011)
Bordetella pertussis employs numerous strategies to evade the immune system, including the ability to resist killing via complement. Previously we have shown that B. pertussis binds a complement regulatory protein, C1 esterase inhibitor (C1inh) to it
Externí odkaz:
https://doaj.org/article/fdb57d26fb084152b6baf3ad38706a9e
Autor:
Doryen Bubeck, Burak V. Kabasakal, Ciaran McFarlane, Charles A. R. Cotton, Nita R. Shah, James W. Murray
In plants, carbon dioxide is fixed via the Calvin cycle in a tightly regulated process. Key to this regulation is the conditionally disordered protein CP12. CP12 forms a complex with two Calvin cycle enzymes, glyceraldehyde-3-phosphate dehydrogenase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e384785a81532677f20b306ee1a1cf14
Autor:
Yuh-Ju Sun, Adrian Goldman, Steven P. D. Harborne, Nita R. Shah, Craig Wilkinson, Ainoleena Turku, Kun-Mou Li, Sarah A. Harris
Publikováno v:
Structural Dynamics
Structural Dynamics, Vol 4, Iss 3, Pp 032105-032105-12 (2017)
Structural Dynamics, Vol 4, Iss 3, Pp 032105-032105-12 (2017)
Membrane-integral pyrophosphatases (mPPases) couple the hydrolysis of pyrophosphate (PPi) to the pumping of Na+, H+, or both these ions across a membrane. Recently solved structures of the Na+-pumping Thermotoga maritima mPPase (TmPPase) and H+-pumpi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e13c338fc523b91cece32175a6c8e81f
http://europepmc.org/articles/PMC5336470
http://europepmc.org/articles/PMC5336470
Publikováno v:
Antimicrobial Agents and Chemotherapy. 58:4931-4934
Bordetella pertussis , the causative agent of whooping cough, has many strategies for evading the human immune system. Lipopolysaccharide (LPS) is an important Gram-negative bacterial surface structure that activates the immune system via Toll-like r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e5b4406cb9afaa3fb9da6a161f0000
https://doi.org/10.1128/aac.02590-14
https://doi.org/10.1128/aac.02590-14
Autor:
Alina Tirsoaga, Nita R. Shah, Soorej M. Basheer, Sami AlBitar-Nehme, Martin Hirst, Malcolm B. Perry, Rachel C. Fernandez, Martine Caroff, Ilaria Trento, Asmaa El Hamidi, Michelle Moksa, Alexey Novikov
Publikováno v:
Innate Immunity. 20:659-672
Endotoxin is recognized as one of the virulence factors of the Bordetella avium bird pathogen, and characterization of its structure and corresponding genomic features are important for an understanding of its role in pathogenicity and for an improve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac83152dcbdf1c1992ad0a7ea46e71ab
https://doi.org/10.1177/1753425913506950
https://doi.org/10.1177/1753425913506950