Zobrazeno 1 - 10
of 238
pro vyhledávání: '"Nissim, Benvenisty"'
Autor:
Matthew M. Edwards, Ning Wang, Ido Sagi, Shay Kinreich, Nissim Benvenisty, Jeannine Gerhardt, Dieter Egli, Amnon Koren
Publikováno v:
Cell Reports, Vol 43, Iss 9, Pp 114700- (2024)
Summary: Genomic imprinting involves differential DNA methylation and gene expression between homologous paternal and maternal loci. It remains unclear, however, whether DNA replication also shows parent-of-origin-specific patterns at imprinted or ot
Externí odkaz:
https://doaj.org/article/2eb1152efe2f44a1a548ec7f56ff265b
Autor:
Shiran Bar, Dan Vershkov, Gal Keshet, Elyad Lezmi, Naama Meller, Atilgan Yilmaz, Ofra Yanuka, Malka Nissim-Rafinia, Eran Meshorer, Talia Eldar-Geva, Nissim Benvenisty
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Genetic imprinting ensures monoallelic gene expression critical for normal embryonic development. Here the authors take advantage of human haploid parthenogenic embryonic stem cells lacking paternal alleles to identify, by genome-wide screening, fact
Externí odkaz:
https://doaj.org/article/207e85234f0e4fce91d514642b759697
Publikováno v:
Cells, Vol 12, Iss 11, p 1503 (2023)
ATM depletion is associated with the multisystemic neurodegenerative syndrome ataxia–telangiectasia (A–T). The exact linkage between neurodegeneration and ATM deficiency has not been established yet, and no treatment is currently available. In th
Externí odkaz:
https://doaj.org/article/bcda169f3acd49e3a59f1f7dcbb3d7a6
Publikováno v:
Cell Division, Vol 14, Iss 1, Pp 1-13 (2019)
Abstract Background Cell cycle regulation is a complex system consisting of growth-promoting and growth-restricting mechanisms, whose coordinated activity is vital for proper division and propagation. Alterations in this regulation may lead to uncont
Externí odkaz:
https://doaj.org/article/2f44c48bdc04448d9b0ba844a7c492e4
Autor:
Uri Weissbein, Mordecai Peretz, Omer Plotnik, Ofra Yanuka, Ido Sagi, Tamar Golan-Lev, Nissim Benvenisty
Publikováno v:
iScience, Vol 11, Iss , Pp 398-408 (2019)
Summary: Human pluripotent stem cells (hPSCs) acquire genetic changes during their propagation in culture that can affect their use in research and future therapies. To identify the key genes involved in selective advantage during culture adaptation
Externí odkaz:
https://doaj.org/article/8c31be471d0a43c081a78132ad044911
Publikováno v:
Stem Cell Reports. 18:1049-1060
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a41b8f446724b03933cc792e8532b808
https://doi.org/10.1016/j.stemcr.2023.04.001
https://doi.org/10.1016/j.stemcr.2023.04.001
Publikováno v:
Stem Cell Reports. 18:817-828
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1516b5abc9caa5f0a8bcbbe882965654
https://doi.org/10.1016/j.stemcr.2023.03.004
https://doi.org/10.1016/j.stemcr.2023.03.004
Modeling Maturity Onset Diabetes of the Young in Pluripotent Stem Cells: Challenges and Achievements
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Maturity onset diabetes of the young (MODY), is a group of monogenic diabetes disorders. Rodent models for MODY do not fully recapitulate the human phenotypes, calling for models generated in human cells. Human pluripotent stem cells (hPSCs), capable
Externí odkaz:
https://doaj.org/article/368e22a4666d4dc9b38a910557ef50b7
Autor:
Roni Sarel-Gallily, Nissim Benvenisty
Publikováno v:
Cells, Vol 11, Iss 11, p 1729 (2022)
X chromosome inactivation is a mammalian dosage compensation mechanism, where one of two X chromosomes is randomly inactivated in female cells. Previous studies have suggested that primed human embryonic stem cells (hESCs) maintain an eroded state of
Externí odkaz:
https://doaj.org/article/0a774c9feb034610a847d43d2a98c4f1
Autor:
Carmel Braverman-Gross, Neta Nudel, Daniel Ronen, Nicola L. Beer, Mark I. McCarty, Nissim Benvenisty
Publikováno v:
Stem Cell Research, Vol 31, Iss , Pp 16-26 (2018)
Maturity onset diabetes of the young (MODY) is a hereditary form of diabetes mellitus presenting at childhood or adolescence, which eventually leads to pancreatic β-cells dysfunction. The underlying genetic basis of MODY disorders is haploinsufficie
Externí odkaz:
https://doaj.org/article/76f385590ae54e559ab10fefaaacc544