Zobrazeno 1 - 10
of 225
pro vyhledávání: '"Nisse Kalkkinen"'
Autor:
Pia Runeberg-Roos, Elisa Piccinini, Anna-Maija Penttinen, Kert Mätlik, Hanna Heikkinen, Satu Kuure, Maxim M. Bespalov, Johan Peränen, Enrique Garea-Rodríguez, Eberhard Fuchs, Mikko Airavaara, Nisse Kalkkinen, Richard Penn, Mart Saarma
Publikováno v:
Neurobiology of Disease, Vol 96, Iss , Pp 335-345 (2016)
In Parkinson's disease midbrain dopaminergic neurons degenerate and die. Oral medications and deep brain stimulation can relieve the initial symptoms, but the disease continues to progress. Growth factors that might support the survival, enhance the
Externí odkaz:
https://doaj.org/article/a3f501f9389e4ae69124b3f661ad8d55
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103101 (2014)
In peroxisomes, peroxins (PEXs) 3 and 19 are the principal protein components of the machinery required for early peroxisomal biogenesis. For further insight into the interaction of PEX3 and PEX19, we used hydrogen exchange mass spectrometry to monit
Externí odkaz:
https://doaj.org/article/7b8914b69bf44d549d835e30520d7b16
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77894 (2013)
B cells play a pivotal role in adaptive immune system, since they maintain a delicate balance between recognition and clearance of foreign pathogens and tolerance to self. During maturation, B cells progress through a series of developmental stages d
Externí odkaz:
https://doaj.org/article/e0daf7a3e0c14337be1ef332e0fc5abe
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8715 (2010)
Specific delivery to synapses of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptors with long-tailed subunits is believed to be a key event in many forms of activity-dependent changes in synaptic strength. GluA1, the best character
Externí odkaz:
https://doaj.org/article/f87f9578c6bc4606b3f6e2e4f6ddef35
Autor:
Marjo Suomalainen, Carmen Buchrieser, Hanna M. Järvinen, Johanna Haiko, Tiira Johansson, Nisse Kalkkinen, Liisa Laakkonen, Timo K. Korhonen, Katri M. Juuti
Publikováno v:
Molecular Microbiology. 89:507-517
Fibrinolysis is important in cell migration and tightly regulated by specific inhibitors and activators; of the latter, urokinase (uPA) associates with enhancement of cell migration. Active uPA is formed through cleavage of the single-chain uPA (scuP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94c6adaa3bd84b5938b7c4a0384f2c9a
https://doi.org/10.1111/mmi.12293
https://doi.org/10.1111/mmi.12293
Autor:
Hanna Heikkinen, Anna-Maija Penttinen, Eberhard Fuchs, Mart Saarma, Kert Mätlik, Pia Runeberg-Roos, Elisa Piccinini, Enrique Garea-Rodriguez, Johan Peränen, Nisse Kalkkinen, Satu Kuure, Mikko Airavaara, Richard Penn, Maxim M. Bespalov
Publikováno v:
Neurobiology of Disease, Vol 96, Iss, Pp 335-345 (2016)
In Parkinson's disease midbrain dopaminergic neurons degenerate and die. Oral medications and deep brain stimulation can relieve the initial symptoms, but the disease continues to progress. Growth factors that might support the survival, enhance the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c192bbe67f88e9e4753b324cc8b3ce89
https://pubmed.ncbi.nlm.nih.gov/27425888
https://pubmed.ncbi.nlm.nih.gov/27425888
Publikováno v:
Annals of Medicine. 45:66-73
Although glial cell line-derived neurotrophic factor (GDNF) has a strong clinical potential, little is known of how the posttranslational modifications of GDNF affect its biological activity and therapeutic potential. In mammalian cells GDNF is synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f9651fe42efc65cbe8cc2a72df1ecf8
https://doi.org/10.3109/07853890.2012.663927
https://doi.org/10.3109/07853890.2012.663927
Autor:
Vesa P. Hytönen, Kirsi Nurminen, Sarah J. Butcher, Vesna Blazevic, Pasi Laurinmäki, Tiia Koho, Markku S. Kulomaa, Nisse Kalkkinen, Timo Vesikari, Gunilla Rönnholm, Leena Huhti
Publikováno v:
Journal of Virological Methods. 179:1-7
Noroviruses are an important cause of epidemic acute gastroenteritis in humans. In this study the production and characterization of GII.4 norovirus virus-like particles (VLPs) in insect cells is reported. Furthermore, the expression of corresponding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b0f874a5bc35bd4f06435325b391840
https://doi.org/10.1016/j.jviromet.2011.05.009
https://doi.org/10.1016/j.jviromet.2011.05.009
Autor:
Kerttu Koskenniemi, Tuula A. Nyman, Matti Kankainen, Petri Auvinen, Kati Laakso, Kirsi Savijoki, Anu Surakka, Johanna Koponen, Nisse Kalkkinen, Pekka Varmanen, Soile Tynkkynen, Tuomas Salusjärvi
Publikováno v:
Microbial Biotechnology. 4:746-766
Summary The growth phase during which probiotic bacteria are harvested and consumed can strongly influence their performance as health-promoting agents. In this study, global transcriptomic and proteomic changes were studied in the widely used probio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0352879702325731ab58f7422f2ca381
https://doi.org/10.1111/j.1751-7915.2011.00275.x
https://doi.org/10.1111/j.1751-7915.2011.00275.x
Publikováno v:
Journal of Bacteriology. 192:4553-4561
Plasminogen activator inhibitor 1 (PAI-1) is a serine protease inhibitor (serpin) and a key molecule that regulates fibrinolysis by inactivating human plasminogen activators. Here we show that two important human pathogens, the plague bacterium Yersi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1652dccb6f46bc39975dc5a98e2581d
https://doi.org/10.1128/jb.00458-10
https://doi.org/10.1128/jb.00458-10