Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nisreen Al-Moghrabi"'
Autor:
Nisreen Al-Moghrabi, Maram Al-Showimi, Nujoud Al-Yousef, Bushra Al-Shahrani, Bedri Karakas, Lamyaa Alghofaili, Hannah Almubarak, Safia Madkhali, Hind Al Humaidan
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-10 (2018)
Abstract Background Constitutive methylation of tumor suppressor genes are associated with increased cancer risk. However, to date, the question of epimutational transmission of these genes remains unresolved. Here, we studied the potential transmiss
Externí odkaz:
https://doaj.org/article/a57d9ef0f1f549208a545219425bb2de
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 10; Pages: 9021
Constitutional BRCA1-methylation is a cancer risk factor for breast (BC) and ovarian (OC) cancer. MiR-155, regulated by BRCA1, is a multifunctional microRNA that plays a crucial role in the immune system. The present study assessed the modulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3722e59130b38c0fc131f70c07325730
Autor:
Maram Al‑Showimi, Nujoud Al‑Yousef, Wejdan Alharbi, Sara Alkhezayem, Osama Almalik, Hamed Alhusaini, Amani Alghamdi, Nisreen Al‑Moghrabi
Publikováno v:
Oncology Letters. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01d6c617c38d4336752559050528726c
https://doi.org/10.3892/ol.2022.13396
https://doi.org/10.3892/ol.2022.13396
Autor:
Layla A. Al-Kharashi, Abdelilah Aboussekhra, Nisreen Al-Moghrabi, Wejdan A AlHarbi, Tala Bakheet
Publikováno v:
Molecular carcinogenesisREFERENCES. 60(11)
Active cancer-associated fibroblasts (CAFs) are major components of the tumor microenvironment, which promote carcinogenesis and modulate response to therapy. Therefore, targeting these cells or reducing their paracrine pro-carcinogenic effects could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::941bf537154af29dbb9a38bb866851d5
https://pubmed.ncbi.nlm.nih.gov/34473867
https://pubmed.ncbi.nlm.nih.gov/34473867
Autor:
Safia Madkhali, Hannah Almubarak, Lamyaa Alghofaili, Maram Al-Showimi, Hind Al Humaidan, Nujoud Al-Yousef, Bushra Al-Shahrani, Nisreen Al-Moghrabi, Bedri Karakas
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-10 (2018)
Clinical Epigenetics
Clinical Epigenetics
Background Constitutive methylation of tumor suppressor genes are associated with increased cancer risk. However, to date, the question of epimutational transmission of these genes remains unresolved. Here, we studied the potential transmission of BR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f81e35a0f648bc68a1faf969e2daa9f
http://link.springer.com/article/10.1186/s13148-018-0529-5
http://link.springer.com/article/10.1186/s13148-018-0529-5
Autor:
Lamyaa Alghofaili, Dilek Colak, Hannah Almubarak, Hamed Alhussaini, Ben Ho Park, Bedri Karakas, Areej Alzahrani, Al Joharah Alhuqail, Sarah Al-Qadheeb, Nisreen Al-Moghrabi
Publikováno v:
Breast Cancer Research and Treatment. 168:695-702
The BRCA1 and BRCA2 (BRCA) genes are heavily involved in mammalian cell DNA repair processes. Germline pathogenic mutations in BRCA increase the lifetime risk of developing breast and/or ovarian cancer in women. In the Arabian Peninsula, most breast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168df2f7fcecb61fbd9cbb738c2facbe
https://doi.org/10.1007/s10549-017-4635-4
https://doi.org/10.1007/s10549-017-4635-4
Publikováno v:
Oncology Reports
Restoration of normal DNA promoter methylation and expression states of cancer-related genes may be an option for the prevention as well as the treatment of several types of cancer. Constitutional promoter methylation of BRCA1 DNA repair associated (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e49114bd1c529480cd459757c05e1eb
https://doi.org/10.3892/or.2020.7473
https://doi.org/10.3892/or.2020.7473
Publikováno v:
Journal of Clinical Epigenetics.
Background: Numerous microRNAs have been categorized as tumor suppressors that are often repressed by aberrant DNA methylation. Recently, BRCA1 promoter methylation in White Blood Cells (WBC) has been linked to elevated risk of developing breast canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e17ca127db64c0cc9f8b8b7793b81091
https://doi.org/10.21767/2472-1158.100037
https://doi.org/10.21767/2472-1158.100037
Autor:
Taher Al-Tweigeri, Ayodele Alaiya, Abdelilah Aboussekhra, Nujoud Al-Yousef, Suad M. Bin Amer, Nisreen Al-Moghrabi, Safia Madkhali, Asma Tulbah, Asmaa Nofel, Zakia Shinwari, Bedri Karakas
Publikováno v:
BMC Cancer
Background BRCA1 promoter methylation has been detected in DNA from peripheral blood cells of both breast cancer patients and cancer-free females. However, the pathological significance of this epigenetic change in white blood cells (WBC) remains an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a2749e942cdd6b82d34af859ecebe5