Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Nishma Chakraborty"'
Autor:
Blake R. Wilde, Nishma Chakraborty, Nedas Matulionis, Stephanie Hernandez, Daiki Ueno, Michayla E. Gee, Edward D. Esplin, Karen Ouyang, Keith Nykamp, Brian Shuch, Heather R. Christofk
The tricarboxylic citric acid cycle enzyme fumarate hydratase (FH) is a tumor suppressor. When lost in cells, its substrate fumarate accumulates to mM levels and drives oncogenic signaling and transformation. Germline alterations lead to an autosomal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5131d506b35353d08376cdeda3b6e78
https://doi.org/10.1101/2022.08.15.504023
https://doi.org/10.1101/2022.08.15.504023
