eQTL in diseased colon tissue identifies novel target genes associated with IBD.

Autor: Nishiyama NC; Curriculum in Bioinformatics and Computational Biology, Department of Genetics, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Center for Gastrointestinal Biology and Disease, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Silverstein S; Center for Gastrointestinal Biology and Disease, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Department of Genetics, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Darlington K; Center for Gastrointestinal Biology and Disease, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Division of Gastroenterology and Hepatology, Department of Medicine, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Kennedy Ng MM; Curriculum in Bioinformatics and Computational Biology, Department of Genetics, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Center for Gastrointestinal Biology and Disease, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Clough KM; Center for Gastrointestinal Biology and Disease, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Curriculum in Toxicology and Environmental Medicine, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Bauer M; Center for Gastrointestinal Biology and Disease, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Beasley C; Center for Gastrointestinal Biology and Disease, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Department of Genetics, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Bharadwaj A; Department of Genetics, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Ganesan R; Department of Genetics, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Kapadia MR; Department of Surgery, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Lau G; Center for Gastrointestinal Biology and Disease, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Lian G; Center for Gastrointestinal Biology and Disease, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Rahbar R; Department of Surgery, REX Healthcare of Wakefield, Raleigh, North Carolina, USA., Sadiq TS; Department of Surgery, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Schaner MR; Center for Gastrointestinal Biology and Disease, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Stem J; Department of Surgery, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Friton J; Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA., Faubion WA Jr; Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA., Sheikh SZ; Center for Gastrointestinal Biology and Disease, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Department of Genetics, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Division of Gastroenterology and Hepatology, Department of Medicine, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Curriculum in Toxicology and Environmental Medicine, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Furey TS; Curriculum in Bioinformatics and Computational Biology, Department of Genetics, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Center for Gastrointestinal Biology and Disease, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Department of Genetics, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 17. Date of Electronic Publication: 2024 Oct 17.

Linking gene expression to clinical outcomes in pediatric Crohn's disease using machine learning.

Autor: Chen KA; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, 7314 Medical Biomolecular Research Building, 111 Mason Farm Road, Chapel Hill, NC, 27599, USA.; Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, USA., Nishiyama NC; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, 7314 Medical Biomolecular Research Building, 111 Mason Farm Road, Chapel Hill, NC, 27599, USA.; Departments of Genetics and Biology, Curriculum in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, 5022 Genetic Medicine Building, 120 Mason Farm Road, Chapel Hill, NC, 27599, USA., Kennedy Ng MM; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, 7314 Medical Biomolecular Research Building, 111 Mason Farm Road, Chapel Hill, NC, 27599, USA.; Departments of Genetics and Biology, Curriculum in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, 5022 Genetic Medicine Building, 120 Mason Farm Road, Chapel Hill, NC, 27599, USA., Shumway A; Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, USA., Joisa CU; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, USA., Schaner MR; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, 7314 Medical Biomolecular Research Building, 111 Mason Farm Road, Chapel Hill, NC, 27599, USA., Lian G; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, 7314 Medical Biomolecular Research Building, 111 Mason Farm Road, Chapel Hill, NC, 27599, USA., Beasley C; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, 7314 Medical Biomolecular Research Building, 111 Mason Farm Road, Chapel Hill, NC, 27599, USA., Zhu LC; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, USA., Bantumilli S; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, USA., Kapadia MR; Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, USA., Gomez SM; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, USA., Furey TS; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, 7314 Medical Biomolecular Research Building, 111 Mason Farm Road, Chapel Hill, NC, 27599, USA. tsfurey@email.unc.edu.; Departments of Genetics and Biology, Curriculum in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, 5022 Genetic Medicine Building, 120 Mason Farm Road, Chapel Hill, NC, 27599, USA. tsfurey@email.unc.edu., Sheikh SZ; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, 7314 Medical Biomolecular Research Building, 111 Mason Farm Road, Chapel Hill, NC, 27599, USA. shehzad_sheikh@med.unc.edu.

Publikováno v: Scientific reports [Sci Rep] 2024 Feb 01; Vol. 14 (1), pp. 2667. Date of Electronic Publication: 2024 Feb 01.

Immunological and hematological outcomes following protracted low dose/low dose rate ionizing radiation and simulated microgravity.

Autor: Paul AM; Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, 94035, USA. amber.m.paul@nasa.gov.; Universities Space Research Association, Columbia, MD, 21046, USA. amber.m.paul@nasa.gov.; Department of Human Factors and Behavioral Neurobiology, Embry-Riddle Aeronautical University, Daytona Beach, FL, 32114, USA. amber.m.paul@nasa.gov., Overbey EG; Department of Genome Sciences, University of Washington, Seattle, WA, 98195, USA., da Silveira WA; Faculty of Medicine, Health and Life Sciences, School of Biological Sciences, Institute for Global Food Security (IGFS), Queen's University, Belfast, BT9 5DL, Northern Ireland, UK., Szewczyk N; Ohio Musculoskeletal and Neurological Institute and Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, OH, 45701, USA., Nishiyama NC; Division of Biomedical Engineering Sciences (BMES), Department of Basic Sciences, Loma Linda University, Loma Linda, CA, 92354, USA., Pecaut MJ; Division of Biomedical Engineering Sciences (BMES), Department of Basic Sciences, Loma Linda University, Loma Linda, CA, 92354, USA., Anand S; Department of Biological Sciences, San Jose University, San Jose, CA, 95192, USA., Galazka JM; Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, 94035, USA., Mao XW; Division of Biomedical Engineering Sciences (BMES), Department of Basic Sciences, Loma Linda University, Loma Linda, CA, 92354, USA.

Publikováno v: Scientific reports [Sci Rep] 2021 Jun 01; Vol. 11 (1), pp. 11452. Date of Electronic Publication: 2021 Jun 01.

Spaceflight induces oxidative damage to blood-brain barrier integrity in a mouse model.

Autor: Mao XW; Department of Basic Sciences, Division of Biomedical Engineering Sciences (BMES), Loma Linda University School of Medicine and Medical Center, Loma Linda, CA, USA., Nishiyama NC; Department of Basic Sciences, Division of Biomedical Engineering Sciences (BMES), Loma Linda University School of Medicine and Medical Center, Loma Linda, CA, USA., Byrum SD; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Arkansas Children's Research Institute, Little Rock, AR, USA., Stanbouly S; Department of Basic Sciences, Division of Biomedical Engineering Sciences (BMES), Loma Linda University School of Medicine and Medical Center, Loma Linda, CA, USA., Jones T; Department of Basic Sciences, Division of Biomedical Engineering Sciences (BMES), Loma Linda University School of Medicine and Medical Center, Loma Linda, CA, USA., Holley J; Department of Basic Sciences, Division of Biomedical Engineering Sciences (BMES), Loma Linda University School of Medicine and Medical Center, Loma Linda, CA, USA., Sridharan V; Division of Radiation Health, Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Boerma M; Division of Radiation Health, Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Tackett AJ; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Arkansas Children's Research Institute, Little Rock, AR, USA., Willey JS; Department of Radiation Oncology, Wake Forest School of Medicine, Winston-Salem, NC, USA., Pecaut MJ; Department of Basic Sciences, Division of Biomedical Engineering Sciences (BMES), Loma Linda University School of Medicine and Medical Center, Loma Linda, CA, USA., Delp MD; Department of Nutrition, Food and Exercise Sciences, Florida State University, Tallahassee, FL, USA.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2020 Nov; Vol. 34 (11), pp. 15516-15530. Date of Electronic Publication: 2020 Sep 26.

Spaceflight influences gene expression, photoreceptor integrity, and oxidative stress-related damage in the murine retina.

Autor: Overbey EG; University of Washington, Department of Genome Sciences, Seattle, WA, USA. eliah@uw.edu., da Silveira WA; Queen's University Belfast, Faculty of Medicine, Health and Life Sciences, School of Biological Sciences, Institute for Global Food Security (IGFS), 19 Chlorine Gardens, Belfast, Northern Ireland, BT9 5DL, UK., Stanbouly S; Department of Basic Sciences, Division of Biomedical Engineering Sciences (BMES), Loma Linda University, Loma Linda, CA, 92350, USA.; Center for Genomics, School of Medicine, Loma Linda University, Loma Linda, CA, 92350, USA., Nishiyama NC; Department of Basic Sciences, Division of Biomedical Engineering Sciences (BMES), Loma Linda University, Loma Linda, CA, 92350, USA., Roque-Torres GD; Center for Dental Research, Loma Linda University, CA, 92354, USA., Pecaut MJ; Department of Basic Sciences, Division of Biomedical Engineering Sciences (BMES), Loma Linda University, Loma Linda, CA, 92350, USA., Zawieja DC; Department of Medical Physiology, Texas A&M University, College Station, Texas, USA., Wang C; Center for Genomics, School of Medicine, Loma Linda University, Loma Linda, CA, 92350, USA., Willey JS; Department of Radiation Oncology, Wake Forest School of Medicine, Winston-Salem, NC, 27157, USA., Delp MD; Department of Nutrition, Food and Exercise Sciences, Florida State University, Tallahassee, FL, 32306, USA., Hardiman G; Queen's University Belfast, Faculty of Medicine, Health and Life Sciences, School of Biological Sciences, Institute for Global Food Security (IGFS), 19 Chlorine Gardens, Belfast, Northern Ireland, BT9 5DL, UK., Mao XW; Department of Basic Sciences, Division of Biomedical Engineering Sciences (BMES), Loma Linda University, Loma Linda, CA, 92350, USA.

Publikováno v: Scientific reports [Sci Rep] 2019 Sep 16; Vol. 9 (1), pp. 13304. Date of Electronic Publication: 2019 Sep 16.