The Derlin-1-Stat5b axis maintains homeostasis of adult hippocampal neurogenesis.

Autor: Murao N; Laboratory of Biochemistry and Molecular Biology, Department of Medical Sciences, University of Miyazaki, Miyazaki, Japan., Matsuda T; Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Kadowaki H; Laboratory of Biochemistry and Molecular Biology, Department of Medical Sciences, University of Miyazaki, Miyazaki, Japan., Matsushita Y; Division of Genome Medicine, Tokushima University, Tokushima, Japan.; National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan., Tanimoto K; High-risk Infectious Disease Control, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan., Katagiri T; Division of Genome Medicine, Tokushima University, Tokushima, Japan.; National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan., Nakashima K; Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. nakashima.kinichi.718@m.kyushu-u.ac.jp., Nishitoh H; Laboratory of Biochemistry and Molecular Biology, Department of Medical Sciences, University of Miyazaki, Miyazaki, Japan. nishitoh@med.miyazaki-u.ac.jp.; Frontier Science Research Center, University of Miyazaki, Miyazaki, Japan. nishitoh@med.miyazaki-u.ac.jp.

Publikováno v: EMBO reports [EMBO Rep] 2024 Aug; Vol. 25 (8), pp. 3678-3706. Date of Electronic Publication: 2024 Jul 30.

Chemical chaperones ameliorate neurodegenerative disorders in Derlin-1-deficient mice via improvement of cholesterol biosynthesis.

Autor: Sugiyama T; Laboratory of Biochemistry and Molecular Biology, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.; Department of Neurology, Faculty of Medicine, University of Miyazaki Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.; Division of Respirology, Rheumatology, Infectious Diseases, and Neurology, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan., Murao N; Laboratory of Biochemistry and Molecular Biology, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan., Kadowaki H; Laboratory of Biochemistry and Molecular Biology, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan., Nishitoh H; Laboratory of Biochemistry and Molecular Biology, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan. nishitoh@med.miyazaki-u.ac.jp.; Frontier Science Research Center, University of Miyazaki, 5200 Kihara Kiyotake, Miyazaki, 889-1692, Japan. nishitoh@med.miyazaki-u.ac.jp.

Publikováno v: Scientific reports [Sci Rep] 2022 Dec 17; Vol. 12 (1), pp. 21840. Date of Electronic Publication: 2022 Dec 17.

ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function.

Autor: Sugiyama T; Laboratory of Biochemistry and Molecular Biology, Department of Medical Sciences, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan., Murao N; Laboratory of Biochemistry and Molecular Biology, Department of Medical Sciences, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan., Kadowaki H; Laboratory of Biochemistry and Molecular Biology, Department of Medical Sciences, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan., Takao K; Department of Behavioral Physiology, Faculty of Medicine, University of Toyama, Toyama 930-0194, Japan.; Research Center for Idling Brain Science, University of Toyama, Toyama, Japan.; Section of Behavioral Patterns, Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, Japan., Miyakawa T; Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi 470-1192, Japan., Matsushita Y; Division of Genome Medicine, Institute for Genome Research, Tokushima University, Tokushima 770-8503, Japan., Katagiri T; Division of Genome Medicine, Institute for Genome Research, Tokushima University, Tokushima 770-8503, Japan., Futatsugi A; Department of Basic Medical Sciences, Kobe City College of Nursing, 3-4 Gakuen-nishi-machi, Nishi-ku, Kobe 651-2103, Japan., Shinmyo Y; Department of Medical Neuroscience, Graduate School of Medical Sciences, Kanazawa University, Kanazawa 920-8640, Japan., Kawasaki H; Department of Medical Neuroscience, Graduate School of Medical Sciences, Kanazawa University, Kanazawa 920-8640, Japan., Sakai J; Division of Metabolic Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo 153-8904, Japan.; Division of Molecular Physiology and Metabolism, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan., Shiomi K; Division of Neurology, Respirology, Endocrinology, and Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan., Nakazato M; Division of Neurology, Respirology, Endocrinology, and Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan., Takeda K; Department of Cell Regulation, Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan., Mikoshiba K; RIKEN Center for Life Science Technologies (CLST), Minatojima-minamimachi, Chuo-ku, Kobe 650-0047, Japan.; Shanghai Institute for Advanced Immunochemical Studies (SIAIS), Shanghai Tech University, Shanghai, China.; Department of Biomolecular Science, Faculty of Science, Toho University, Funabashi, Japan., Ploegh HL; Boston Children's Hospital and Harvard Medical School, 1 Blackfan Circle, Boston, MA 02115, USA., Ichijo H; Laboratory of Cell Signaling, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan., Nishitoh H; Laboratory of Biochemistry and Molecular Biology, Department of Medical Sciences, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan.; Frontier Science Research Center, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan.

Publikováno v: IScience [iScience] 2021 Jun 19; Vol. 24 (7), pp. 102758. Date of Electronic Publication: 2021 Jun 19 (Print Publication: 2021).

Navigating the redox landscape: reactive oxygen species in regulation of cell cycle.

Autor: Mackova, Viktoria¹ (AUTHOR), Raudenska, Martina^1,2 (AUTHOR), Polanska, Hana Holcova^1,2 (AUTHOR), Jakubek, Milan³ (AUTHOR), Masarik, Michal^1,2,3,4 (AUTHOR) masarik@med.muni.cz

Publikováno v: Redox Report. Dec2024, Vol. 29 Issue 1, p1-18. 18p.

Unraveling Macrophage Polarization: Functions, Mechanisms, and "Double-Edged Sword" Roles in Host Antiviral Immune Responses.

Autor: Yao, Meng^1,2 (AUTHOR) a13678602285@163.com, Li, Meilin¹ (AUTHOR) m18037901611@163.com, Peng, Dingkun¹ (AUTHOR) pengdk11@163.com, Wang, Yijing¹ (AUTHOR) 15039269261@163.com, Li, Su¹ (AUTHOR) lisu@caas.cn, Zhang, Ding² (AUTHOR) bo_yang@sxau.edu.cn, Yang, Bo² (AUTHOR), Qiu, Hua-Ji¹ (AUTHOR) qiuhuaji@caas.cn, Li, Lian-Feng^1,2 (AUTHOR) qiuhuaji@caas.cn

Publikováno v: International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 22, p12078. 24p.