Zobrazeno 1 - 10
of 8 307
pro vyhledávání: '"Nishimune, A"'
Autor:
Omar Jawdat, Jason Rucker, Tomoki Nakano, Kotaro Takeno, Jeffery Statland, Mamatha Pasnoor, Mazen M. Dimachkie, Carla Sabus, Yomna Badawi, Suzanne L. Hunt, Naoko H. Tomioka, Sumedha Gunewardena, Clark Bloomer, Heather M. Wilkins, Laura Herbelin, Richard J. Barohn, Hiroshi Nishimune
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Amyotrophic lateral sclerosis (ALS) patients lack effective treatments to maintain motor and neuromuscular function. This study aimed to evaluate the effect of a home-based exercise program on muscle strength, ALS scores, and transcriptome i
Externí odkaz:
https://doaj.org/article/e3237184e1bb4c6f98062c0787594ebf
Autor:
Ikko Sakamoto, Shuichi Shibuya, Hidetoshi Nojiri, Kotaro Takeno, Hiroshi Nishimune, Keisuke Yaku, Takashi Nakagawa, Muneaki Ishijima, Takahiko Shimizu
Publikováno v:
Antioxidants, Vol 13, Iss 11, p 1421 (2024)
Mitochondria and glycogen are co-distributed in skeletal muscles to regulate the metabolic status. Mitochondria are also redox centers that regulate the muscle function during exercise. However, the pathophysiological relationship between the mitocho
Externí odkaz:
https://doaj.org/article/7bf8fbb4ba8e43368ef6ee38150cd1d9
Akademický článek
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Autor:
Inoue, Ritsuko1 (AUTHOR) inoritu@tmig.or.jp, Nishimune, Hiroshi1,2 (AUTHOR) nishimun@tmig.or.jp
Publikováno v:
Cells (2073-4409). Sep2023, Vol. 12 Issue 17, p2142. 17p.
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Physiological aging causes motor function decline and anatomical and biochemical changes in the motor cortex. We confirmed that middle-aged mice at 15–18 months old show motor function decline, which can be restored to the young adult leve
Externí odkaz:
https://doaj.org/article/3231155f04094e0fb3d820c8408f9d08
Akademický článek
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Publikováno v:
NeuroReport; 8/15/2024, Vol. 35 Issue 12, p805-810, 6p
Autor:
Ritsuko Inoue, Hiroshi Nishimune
Publikováno v:
Cells, Vol 12, Iss 17, p 2142 (2023)
Physiological aging causes a decline of motor function due to impairment of motor cortex function, losses of motor neurons and neuromuscular junctions, sarcopenia, and frailty. There is increasing evidence suggesting that the changes in motor functio
Externí odkaz:
https://doaj.org/article/53e94c36a6c14f378b4fc17ed8a9cf4b
Autor:
Sudheer K. Tungtur, Heather M. Wilkins, Robert S. Rogers, Yomna Badawi, Jessica M. Sage, Abdulbaki Agbas, Omar Jawdat, Richard J. Barohn, Russell H. Swerdlow, Hiroshi Nishimune
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Amyotrophic lateral sclerosis (ALS) remains a devastating motor neuron disease with limited treatment options. Oxaloacetate treatment has a neuroprotective effect in rodent models of seizure and neurodegeneration. Therefore, we treated the A
Externí odkaz:
https://doaj.org/article/38dec4f7c64841b98b4be34960b67c6f
Autor:
Funk, Steven D., Bayer, Raymond H., McKee, Karen K., Okada, Kazushi, Nishimune, Hiroshi, Yurchenco, Peter D., Miner, Jeffrey H.
Publikováno v:
In Kidney International July 2020 98(1):133-146