Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nishani S. Mabotuwana"'
Autor:
Jacinta H. Martin, Ilana R. Bernstein, Jess M. Lyons, Ariel R. Brady, Nishani S. Mabotuwana, Simone J. Stanger, Camila Salum De Oliveira, Katerina B. Damyanova, Brett Nixon, Tessa Lord
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Oxygen availability can have profound effects on cell fate decisions and survival, in part by regulating expression of hypoxia-inducible factors (HIFs). In the ovary, HIF expression has been characterised in granulosa cells, however, any req
Externí odkaz:
https://doaj.org/article/5dda65dc8bf448c0add10432000f1a06
Autor:
Lucy A. Murtha, Sean A. Hardy, Nishani S. Mabotuwana, Mark J. Bigland, Taleah Bailey, Kalyan Raguram, Saifei Liu, Doan T. Ngo, Aaron L. Sverdlov, Tamara Tomin, Ruth Birner-Gruenberger, Robert D. Hume, Siiri E. Iismaa, David T. Humphreys, Ralph Patrick, James J. H. Chong, Randall J. Lee, Richard P. Harvey, Robert M. Graham, Peter P. Rainer, Andrew J. Boyle
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Despite the high prevalence of heart failure in the western world, there are few effective treatments. Fibulin-3 is a protein involved in extracellular matrix (ECM) structural integrity, however its role in the heart is unknown. We have demo
Externí odkaz:
https://doaj.org/article/a7e2f43b7c7844a0a23cc1ccd8d00927
Autor:
Ilana R. Bernstein, Brett Nixon, Jess M. Lyons, Katerina B. Damyanova, Camila S. De Oliveira, Nishani S. Mabotuwana, Simone J. Stanger, Gerard E. Kaiko, Tan Hui Ying, Jon M. Oatley, Nicole M. Skillen, Alyssa J. Lochrin, Jera L. Peters, Tessa Lord
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108424- (2023)
Summary: In this study we explored the role of hypoxia and the hypoxia-inducible transcription factor EPAS1 in regulating spermatogonial stem cell (SSC) function in the mouse testis. We have demonstrated that SSCs reside in hypoxic microenvironments
Externí odkaz:
https://doaj.org/article/2fa4f90c3ac04a43b6a08638c06119ad
Autor:
Lucy A. Murtha, Michael J. Schuliga, Nishani S. Mabotuwana, Sean A. Hardy, David W. Waters, Janette K. Burgess, Darryl A. Knight, Andrew J. Boyle
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Fibrosis is the formation of fibrous connective tissue in response to injury. It is characterized by the accumulation of extracellular matrix components, particularly collagen, at the site of injury. Fibrosis is an adaptive response that is a vital c
Externí odkaz:
https://doaj.org/article/79794bcdc8374fababf7f4707252004d
Publikováno v:
International Journal of Cardiology. 376:1-10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::763c774d884cc8e1493cea6325c4d529
https://doi.org/10.1016/j.ijcard.2023.01.082
https://doi.org/10.1016/j.ijcard.2023.01.082
Autor:
Sean A Hardy, Nishani S Mabotuwana, Lucy A Murtha, Brianna Coulter, Sonia Sanchez-Bezanilla, Mohammed S Al-Omary, Tharindu Senanayake, Svenja Loering, Malcolm Starkey, Randall J Lee, Peter P Rainer, Philip M Hansbro, Andrew J Boyle
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212230 (2019)
IntroductionThe prevalence of heart failure increases in the aging population and following myocardial infarction (MI), yet the extracellular matrix (ECM) remodeling underpinning the development of aging- and MI-associated cardiac fibrosis remains po
Externí odkaz:
https://doaj.org/article/8aa2f4e61bae41cd99a833a4e5636448
Autor:
Nishani S. Mabotuwana, Lavinia Rech, Joyce Lim, Sean A. Hardy, Lucy A. Murtha, Peter P. Rainer, Andrew J. Boyle
Publikováno v:
Stem cell reviews and reports. 18(8)
Mesenchymal stem cell (MSC) therapy has gained significant traction in the context of cardiovascular repair, and have been proposed to exert their regenerative effects via the secretion of paracrine factors. In this systematic review, we examined the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2587c5d169715dcf3675caa5009fc509
https://pubmed.ncbi.nlm.nih.gov/35896860
https://pubmed.ncbi.nlm.nih.gov/35896860