Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nisha Susan Thomas"'
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 195:821-829
Two series of thiazinone and thiosemicarbazone derivatives (1-12) were synthesized using 2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ones (ABNs) and 3–alkyl–2,6–diarylpiperidin–4–ones as the starting materials. The structures of newly synthesized
Publikováno v:
Toxicology Mechanisms and Methods. 30:358-369
The stilbene derivative, 4,4′-diisothiocyanatostilbene-2,2′-disulphonic acid (DIDS), an anion channel blocker is used in the present study to evaluate its modulatory effect on voltage-gated K+ current (IK) in human prostate cancer cell lines (LNC
Publikováno v:
The Journal of Membrane Biology. 252:195-206
Phytochemicals are ubiquitous in naturally occurring dietary elements that exhibits diverse pharmacological properties over various pathological disorders, including cancer. Voltage gated K+ (KV) channel in the plasma membrane contributes to wide ran
Publikováno v:
Archives of Biochemistry and Biophysics. 667:36-48
Piperine is an attractive therapeutic alkaloid from black pepper that exhibits a broad spectrum of pharmacological properties over various pathological disorders including cancer. Voltage gated K+ (KV) channels play an important role in regulating ca
Publikováno v:
Toxicology in Vitro. 54:317-329
Troxerutin (TX), a bioflavonoid widely present in various fruits and vegetables, has shown to exhibit numerous pharmacological properties including anti-neoplastic and anti-cancer activities. Nrf2 and NF-κB are the key transcription factors that reg
Autor:
Sivaranjani Arivalagan, Nisha Susan Thomas, Balaji Chandrasekaran, Vijay Mani, Aktarul Islam Siddique, Thayalan Kuppsamy, Nalini Namasivayam
Publikováno v:
Molecular and Cellular Biochemistry. 477:329-330
Publikováno v:
Toxicology mechanisms and methods. 30(5)
The stilbene derivative, 4,4'-diisothiocyanatostilbene-2,2'-disulphonic acid (DIDS), an anion channel blocker is used in the present study to evaluate its modulatory effect on voltage-gated K
Autor:
Nisha Susan Thomas, Aktarul Islam Siddique, Sivaranjani Arivalagan, Vijay Mani, Nalini Namasivayam
Publikováno v:
Toxicology Mechanisms and Methods. 27:136-150
Asiatic acid (AA), a pentacyclic triterpenoid, derived from the tropical medicinal plant Centella asiatica is known to exhibit numerous pharmacological properties. We hypothesized that AA will have chemopreventive potential against 1,2-dimethylhydraz
Autor:
Nalini Namasivayam, Nisha Susan Thomas, Sivaranjani Arivalagan, Kiran George, Aktarul Islam Siddique, Vijay Mani
Publikováno v:
European Journal of Nutrition. 56:2353-2366
Troxerutin (TXER), a trihydroxyethylated derivative of the natural bioflavonoid rutin, abundantly found in tea, various fruits and vegetables, is known to exhibit ample pharmacological properties. In the present investigation, we examined the antineo
Autor:
Antony Therasa Alphonsa, K. Saravanan, Senthamaraikannan Kabilan, C. Loganathan, Selvam Athavan Alias Anand, Nisha Susan Thomas
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 191:1396-1401
A novel series of 1,3-thiazin-4-one derivatives containing a piperidyl ring (7–16) were designed and synthesized efficiently by thioamide and acetylene diester cyclization reaction via aminolysis of the ester group and the elimination of an alcohol