Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Nisa Renault"'
Autor:
Manon Desgres, Bruna Lima Correa, Lorena Petrusca, Gwennhael Autret, Chloé Pezzana, Céline Marigny, Chloé Guillas, Valérie Bellamy, José Vilar, Marie-Cécile Perier, Florent Dingli, Damarys Loew, Camille Humbert, Jérôme Larghero, Guillaume Churlaud, Nisa Renault, Pierre Croisille, Albert Hagège, Jean-Sébastien Silvestre, Philippe Menasché
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundCurrent treatments of chemotherapy-induced cardiomyopathy (CCM) are of limited efficacy. We assessed whether repeated intravenous injections of human extracellular vesicles from cardiac progenitor cells (EV-CPC) could represent a new therap
Externí odkaz:
https://doaj.org/article/5374d51a15114ea6a6d1bd5f0f274719
Autor:
Sisareuth Tan, Jean-Sébastien Silvestre, Kamaleswaran Keirththana, Alain Brisson, Thi Anh-Dao Tran, José Vilar, Philippe Menasché, Paul Alayrac, Thomas Hamada, Maria Franca Perotto, Nadia El Harane, Reem Al-Daccak, Dominique Charron, Laetitia Pidial, Valérie Bellamy, Nisa Renault, Hocine Rachid Hocine, Chloé Guillas, Manon Desgres, Ingrid Gomez, Bruna Lima Correa
Publikováno v:
Cardiovascular Research
Cardiovascular Research, Oxford University Press (OUP), 2020, pp.cvaa028. ⟨10.1093/cvr/cvaa028⟩
Cardiovascular Research, 2020, pp.cvaa028. ⟨10.1093/cvr/cvaa028⟩
Cardiovascular Research, Oxford University Press (OUP), 2020, pp.cvaa028. ⟨10.1093/cvr/cvaa028⟩
Cardiovascular Research, 2020, pp.cvaa028. ⟨10.1093/cvr/cvaa028⟩
AimsThe cardioprotective effects of human induced pluripotent stem cell-derived cardiovascular progenitor cells (CPC) are largely mediated by the paracrine release of extracellular vesicles (EV). We aimed to assess the immunological behaviour of EV-C
Autor:
Bruna, Lima Correa, Nadia, El Harane, Manon, Desgres, Maria, Perotto, Paul, Alayrac, Chloé, Guillas, Laetitia, Pidial, Valérie, Bellamy, Emilie, Baron, Gwennhael, Autret, Keirththana, Kamaleswaran, Chloé, Pezzana, Marie-Cécile, Perier, José, Vilar, Antonio, Alberdi, Alain, Brisson, Nisa, Renault, Massimiliano, Gnecchi, Jean-Sébastien, Silvestre, Philippe, Menasché
Publikováno v:
Theranostics
Background: Extracellular vesicles (EV) mediate the therapeutic effects of stem cells but it is unclear whether this involves cardiac regeneration mediated by endogenous cardiomyocyte proliferation. Methods: Bi-transgenic MerCreMer/ZEG (n = 15/group)
Autor:
Massimiliano Gnecchi, noemie tence, Emilie Baron, Philippe Menasché, Nadia El Harane, Bruna Lima Correa, Chloé Guillas, Jean-Sébastien Silvestre, Manon Desgres, Maria Perotto, Antonio Alberdi, Keirththana Kamaleswaran, José Vilar, Valérie Bellamy, Laetitia Pidial, Nisa Renault, Gwennhael Autret, Paul Alayrac
Publikováno v:
Circulation. 142
Introduction: Extracellular Vesicles (EV) recapitulate the benefits of cell therapy for heart repair. Their mechanism of action remains unsettled. Hypothesis: EV may contribute to heart repair by de novo cardiogenesis. Methods: To answer this questio
Autor:
Solenne Paiva, Nadia El Harane, Jean-Sébastien Silvestre, Yeranuhi Hovhannisyan, Camille Brunaud, Léa Thiebault, Jeanne Gauthier, Onnik Agbulut, Marc P. Renault, Philippe Menasché, Hany J Neametalla, Marie-Cécile Perier, Nicolas Cagnard, Albert Hagège, Mathilde Lemitre, Bruna Lima Correa, Valérie Bellamy, Angéline Duché, Anaïs Kervadec, Alexandra T Bourdillon, Nisa Renault, Laetitia Pidial, Alexandre R. Colas
Publikováno v:
European Heart Journal. 39:1835-1847
Aims We have shown that extracellular vesicles (EVs) secreted by embryonic stem cell-derived cardiovascular progenitor cells (Pg) recapitulate the therapeutic effects of their parent cells in a mouse model of chronic heart failure (CHF). Our objectiv
Autor:
Manon Desgres, Maria Perotto, Jean-Sébastien Silvestre, B. Lima Correa, Marie Cécile Perier, N. El Harane, Valérie Bellamy, Philippe Menasché, E Barron, Nisa Renault, Massimiliano Gnecchi, Laetitia Pidial, noemie tence
Publikováno v:
European Heart Journal. 40
Introduction Extracellular Vesicles (EV) seem to mediate the benefits of cell therapy for ischemic heart failure. Although their mechanism of action remains poorly understood, one hypothesis is that they might trigger the generation of new cardiomyoc
Publikováno v:
Materials Letters. 282:128671
Extracellular vesicles (EVs) are cell-derived bodies proven to have a wide range of therapeutic applications. To date, EVs have almost always been administered by direct injection, which is very likely to hinder their efficacy because of rapid cleara
Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction
Autor:
Luca Danelli, Maxime Branchereau, Eric Camerer, Mathilde Lemitre, Nisa Renault, Béatrice Cousin, Pauline Marck, Adèle Richart, Elodie Luche, Pierre Launay, Sylvain M. Le Gall, Coralie L. Guerin, Jean-Sébastien Silvestre, Anta Ngkelo, Philippe Bonnin, Anaïs Kervadec, Jonathan A. Kirk, Hans Reimer Rodewald, Philippe Menasché, Mark J. Ranek, Patrick Bruneval, Christophe Heymes, José Vilar, Ulrich Blank, David A. Kass, Gregory Gautier, Louis Casteilla
Publikováno v:
The Journal of Experimental Medicine
Ngkelo et al. use a mast cell–deficient mouse model to reveal a protective role of mast cells in myocardial infarction, through regulation of the cardiac contractile machinery.
Acute myocardial infarction (MI) is a severe ischemic disease resp
Acute myocardial infarction (MI) is a severe ischemic disease resp
Autor:
Min Yin, Valérie Vanneaux, Albert Hagège, Nadia El Harane, Jean-Sébastien Silvestre, Adèle Richart, Chantal M. Boulanger, Hany Nemetalla, Anaïs Kervadec, Marie Cécile Perier, Jérôme Larghero, Hadi Toeg, Marc Ruel, Nisa Renault, Valérie Bellamy, Mathilde Lemitre, Xavier Loyer, Isabelle Cacciapuoti, Philippe Menasché, Lousineh Arakelian
Publikováno v:
The Journal of Heart and Lung Transplantation. 35:795-807
Background Cell-based therapies are being explored as a therapeutic option for patients with chronic heart failure following myocardial infarction. Extracellular vesicles (EV), including exosomes and microparticles, secreted by transplanted cells may
Autor:
Gwennhael Autret, Jean-Sébastien Silvestre, B. Lima Correa, Keirththana Kamaleswaran, N. El Harane, Massimiliano Gnecchi, Antonio Alberdi, Nisa Renault, Philippe Menasché, Maria Perotto, Chloé Guillas, Manon Desgres, noemie tence, Valérie Bellamy, Emilie Baron, Laetitia Pidial, José Vilar
Publikováno v:
Cytotherapy. 22:S189
Background & Aim Introduction Cell therapy for chronic heart failure has demonstrated that Cardiac Progenitor Cells (CPCs) delivered to the heart exert their beneficial effects through a paracrine mechanism harnessing endogenous repair pathways large