Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nis Valentin Nielsen"'
Autor:
Sebastian Seidl, Nis Valentin Nielsen, Michael Escheid, Bengt Erik Haug, Maria Stensland, Bernd Thiede, Paul J. Declerck, Geir Åge Løset, Sandip M. Kanse
Increased Factor VII activating protease (FSAP) activity has a protective effect in diverse disease conditions as inferred from studies in FSAP−/− mice and humans deficient in FSAP activity due to a single nucleotide polymorphism. The activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1bab935607a25f3e39e2a20180ce336
https://doi.org/10.1101/2022.01.09.475526
https://doi.org/10.1101/2022.01.09.475526
Autor:
Sebastian Berge-Seidl, Nis Valentin Nielsen, Armando A. Rodriguez Alfonso, Michael Etscheid, Sai Priya Sarma Kandanur, Bengt Erik Haug, Maria Stensland, Bernd Thiede, Merve Karacan, Nico Preising, Sebastian Wiese, Ludger Ständker, Paul J. Declerck, Geir Åge Løset, Sandip M. Kanse
Publikováno v:
ACS Chemical Biology
2631–2642
2631–2642
Factor VII Activating protease (FSAP) has a protective effect in diverse disease conditions as inferred from studies in FSAP-/- mice and humans deficient in FSAP activity due to single-nucleotide polymorphism. The zymogen form of FSAP in plasma is ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::575d9f37fe86a28755688db593e0dc61
https://hdl.handle.net/11250/3029761
https://hdl.handle.net/11250/3029761
Autor:
Sandip M. Kanse, Emrah Kara, Geir Åge Løset, Nis Valentin Nielsen, Bernd Thiede, Bergrun Eggertsdottir
Publikováno v:
Chembiochem
We describe a novel, easy and efficient combinatorial phage display peptide substrate‐mining method to map the substrate specificity of proteases. The peptide library is displayed on the pVII capsid of the M13 bacteriophage, which renders pIII nece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc4740cb518b025337a0b548e12d999
http://hdl.handle.net/10852/83328
http://hdl.handle.net/10852/83328
Autor:
Nis Valentin Nielsen, Michael Etscheid, Jens Preben Morth, Elfie Kathrin Roedel, Sandip M. Kanse, Dipankar Manna
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Factor VII (FVII) activating protease (FSAP) is a circulating serine protease. Human genetic studies, based on the Marburg I (MI) (Gly221Glu, chymotrypsin numbering system) polymorphism, implicate FSAP in the pathogenesis of many diseases. Here, we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56bcc2bf3e0826bf5acaa0b5967bf3b1
https://doi.org/10.1038/s41598-019-55531-x
https://doi.org/10.1038/s41598-019-55531-x
Autor:
Marcin Poreba, Marcin Drag, Sandip M. Kanse, Wioletta Rut, Nis Valentin Nielsen, Justyna Czarna
Publikováno v:
Thrombosis research. 182
The zymogen form of circulating Factor VII activating protease (FSAP) is activated by histones that are released as a consequence of tissue damage or excessive inflammation. This is likely to have consequences in a number of disease conditions such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c7ae60baffea3b37297bb9d3fac4da
https://pubmed.ncbi.nlm.nih.gov/31479940
https://pubmed.ncbi.nlm.nih.gov/31479940
Autor:
Nis Valentin Nielsen, Paul F. Ruehle, Sandip M. Kanse, Kristina Byskov, Michael Etscheid, Thomas Boettger
Background and aims The factor VII activating protease (FSAP) knockout mice have a bigger neointima after vascular injury and a larger infarct volume after stroke. The Marburg I (MI) single nucleotide polymorphism (SNP) in the FSAP-encoding gene is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46799d5daab597948df12be137fe6bd1
http://hdl.handle.net/10852/61830
http://hdl.handle.net/10852/61830
Autor:
Jan K. Jensen, Jette Bornholdt, Stine Friis, Roman Szabo, Martin N. Andersen, Simon D.R. Steffensen, Brian Roland Larsen, Hanne Skovbjerg, Thomas H. Bugge, Steen Seier Poulsen, Sine Godiksen, Lotte K. Vogel, Christoffer Soendergaard, Nis Valentin Nielsen, Chen-Yong Lin, Annika W. Nonboe
Hepatocyte growth factor activator inhibitor-2 (HAI-2) is an inhibitor of many proteases in vitro, including the membrane-bound serine protease, matriptase. Studies of knock-out mice have shown that HAI-2 is essential for placental development only i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31db602672f1b673e4bb2cd77c15376a
https://europepmc.org/articles/PMC4810019/
https://europepmc.org/articles/PMC4810019/