Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Nirupama Ramkumar"'
Autor:
Benjamin Werbner, Sophie L. Stephens, Deborah Stuart, Travis M. Hotchkiss, Jonathan Chapman, Katsuhiko Funai, Nirupama Ramkumar, Sihem Boudina
Publikováno v:
Physiological Reports, Vol 12, Iss 18, Pp n/a-n/a (2024)
Abstract Heart failure with preserved ejection fraction (HFpEF) has recently emerged as an insidiously and increasingly prevalent heart failure phenotype. HFpEF often occurs in the context of hypertension and obesity and presents with diastolic dysfu
Externí odkaz:
https://doaj.org/article/f099b5b9c0cc4ef2bef72b1e83637edf
Evaluation of renal sodium handling in heart failure with preserved ejection fraction: A pilot study
Autor:
Adhish Agarwal, Srinivasan Beddhu, Robert Boucher, Veena Rao, Nirupama Ramkumar, Aylin R. Rodan, Jacob Fang, Brandi M. Wynne, Stavros G. Drakos, Thomas Hanff, Alfred K. Cheung, James C. Fang
Publikováno v:
Physiological Reports, Vol 12, Iss 9, Pp n/a-n/a (2024)
Abstract The pathophysiology behind sodium retention in heart failure with preserved ejection fraction (HFpEF) remains poorly understood. We hypothesized that patients with HFpEF have impaired natriuresis and diuresis in response to volume expansion
Externí odkaz:
https://doaj.org/article/9ffcb949c276407eb186eebff289d4e5
Autor:
Kai Song, Deborah Stuart, Nikita Abraham, Fei Wang, Shuping Wang, Tianxin Yang, Curt D Sigmund, Donald E Kohan, Nirupama Ramkumar
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159872 (2016)
Collecting duct (CD)-derived renin is involved in the hypertensive response to chronic angiotensin-II (Ang-II) administration. However, whether CD renin is involved in Ang-II independent hypertension is currently unknown. To begin to examine this, 12
Externí odkaz:
https://doaj.org/article/9f99f98c5df04f83bd498281073c64d7
Autor:
Justin P. Van Beusecum, Fitra Rianto, Jade Teakell, Valentina Kon, Matthew A. Sparks, Ewout J. Hoorn, Annet Kirabo, Nirupama Ramkumar
Publikováno v:
Advances in Kidney Disease and Health. 30:124-136
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab6157b6b84ceb7599a57e6e4331d6f6
https://doi.org/10.1053/j.akdh.2022.12.007
https://doi.org/10.1053/j.akdh.2022.12.007
Autor:
Hui Lin, Frank Geurts, Luise Hassler, Daniel Batlle, Katrina M. Mirabito Colafella, Kate M. Denton, Jia L. Zhuo, Xiao C. Li, Nirupama Ramkumar, Masahiro Koizumi, Taiji Matsusaka, Akira Nishiyama, Martin J. Hoogduijn, Ewout J. Hoorn, A.H. Jan Danser
Publikováno v:
Pharmacological Reviews. 74:462-505
——The concept of local formation of angiotensin II in the kidney has changed over the last 10–15 years. Local synthesis of angiotensinogen in the proximal tubule has been proposed, combined with prorenin synthesis in the collecting duct. Bindin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dded95b90843083437cc42757f5b60ea
https://doi.org/10.1124/pharmrev.120.000236
https://doi.org/10.1124/pharmrev.120.000236
Publikováno v:
Physiology. 38
Background: Cleavage of the extra-cellular domain of the (pro)renin receptor (PRR) yields a soluble fragment (sPRR), that has been implicated in the pathogenesis of hypertension. We recently developed a novel mouse model with mutation in the cleavage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::661f4b349472ffa3df7aaef925a73a7a
https://doi.org/10.1152/physiol.2023.38.s1.5735305
https://doi.org/10.1152/physiol.2023.38.s1.5735305
Publikováno v:
Advances in Kidney Disease and Health. 30:69-70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70c4e23b78124fe578a99e9ccee4d19b
https://doi.org/10.1053/j.akdh.2023.01.006
https://doi.org/10.1053/j.akdh.2023.01.006
Publikováno v:
The American Journal of the Medical Sciences. 365:313-314
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12df23496f420a40758b74beeb4c90e1
https://doi.org/10.1016/j.amjms.2022.12.011
https://doi.org/10.1016/j.amjms.2022.12.011
Autor:
Chuanming Xu, Yanting Chen, Nirupama Ramkumar, Chang‐Jiang Zou, Curt D. Sigmund, Tianxin Yang
Publikováno v:
Acta physiologica (Oxford, England)REFERENCES. 237(1)
The kaliuretic action of the renin-angiotensin-aldosterone system (RAAS) is well established as highlighted by hyperkalemia side effect of RAAS inhibitors but such action is usually ascribed to systemic RAAS. The present study addresses the involveme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::052a935e44d87c44587e82e10a7b7bd6
https://pubmed.ncbi.nlm.nih.gov/36264268
https://pubmed.ncbi.nlm.nih.gov/36264268
Autor:
Masaaki Yoshigi, Deborah Stuart, Kennedy Koehler, Harini Srinivasan, Douglas C Eaton, Nirupama Ramkumar, Brandi M Wynne
Publikováno v:
Hypertension. 79
Hypertension (HTN) is associated with an increase in pro-inflammatory cytokines. Sentinel renal dendritic cells (rDCs) form an intricate network within the kidney cortex. DCs can activate immune cells and secrete pro-inflammatory cytokines. We hypoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ebfffdbd107157d7aa5f72443982ba2
https://doi.org/10.1161/hyp.79.suppl_1.005
https://doi.org/10.1161/hyp.79.suppl_1.005