Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Nirupama K. Shevde"'
Autor:
Jayne M Squirrell, Jimmy J Fong, Carlos A Ariza, Amber Mael, Kassondra Meyer, Nirupama K Shevde, Avtar Roopra, Gary E Lyons, Timothy J Kamp, Kevin W Eliceiri, Brenda M Ogle
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43708 (2012)
The therapeutic potential of stem cells is limited by the non-uniformity of their phenotypic state. Thus it would be advantageous to noninvasively monitor stem cell status. Driven by this challenge, we employed multidimensional multiphoton microscopy
Externí odkaz:
https://doaj.org/article/36ef4ca9d3c44326a4d66fe5b8c8a324
Autor:
Jackie A. Fretz, Mark B. Meyer, Lee A. Zella, Sungtae Kim, Nirupama K. Shevde, Miwa Yamazaki, Makoto Watanuki, J. Wesley Pike
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 103:389-395
1,25-Dihydroxyvitamin D3 (1,25(OH)2D3) functions as a systemic signal in vertebrate organisms to control the expression of genes whose products are vital to the maintenance of calcium and phosphorus homeostasis. This regulatory capability is mediated
Publikováno v:
Molecular Endocrinology. 20:1447-1461
Transient receptor potential vanilloid type 6 (TRPV6) (ECAC2, CaT1) is the major ion channel in intestinal epithelial cell membranes responsible for calcium entry. Its expression is actively regulated at the transcriptional level by 1,25-dihydroxyvit
Publikováno v:
Molecular Endocrinology. 20:1231-1247
The biological actions of 1,25-(OH)2D3 are mediated by the vitamin D receptor (VDR), a protein that binds to target genes and alters their expression. 1,25-(OH)2D3 is also capable of inducing transcription of the VDR gene itself. In the present study
Autor:
Hironori Yamamoto, J. Wesley Pike, Lori A. Plum, Anjali C. Warrier, Hector F. DeLuca, Nirupama K. Shevde
Publikováno v:
Journal of Biological Chemistry. 278:31756-31765
2-Methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 (2MD) is a highly potent analog of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) whose actions are mediated through the vitamin D receptor (VDR). In this report, we have replicated this increased potency of
Autor:
Ching-Yi Chang, Peterson Pathrose, Donald P. McDonnell, J. Wesley Pike, Olga Barmina, Nirupama K. Shevde
Publikováno v:
Journal of Bone and Mineral Research. 17:2196-2205
The vitamin D receptor (VDR) is known to mediate the biological actions of 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] through its ability to regulate cellular programs of gene expression. Although RXR appears to participate as a heterodimeric partner wit
Autor:
Ching-Yi Chang, Olga Barmina, Peterman Pathrose, Nirupama K. Shevde, Donald P. McDonnell, Hironori Yamamoto, J. Wesley Pike
Publikováno v:
Journal of Cellular Biochemistry. 88:252-258
The vitamin D receptor (VDR) is known to mediate the biological actions of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) through its ability to regulate cellular programs of gene expression. We identified VDR- and retinoid X receptor (RXR)-interacting LXXLL
Autor:
J. Wesley Pike, Hector F. DeLuca, Hironori Yamamoto, Lori A. Plum, Margaret Clagett-Dame, Nirupama K. Shevde
Publikováno v:
Proceedings of the National Academy of Sciences. 99:13487-13491
1,25-Dihydroxyvitamin D 3 [1,25(OH) 2 D 3 ] is a principal regulator of calcium and phosphorus homeostasis through actions on intestine, kidney, and bone. 1,25(OH) 2 D 3 is not considered to play a significant role in bone formation, except for its r
Autor:
Yongwon Choi, Joseph R. Arron, Deena Segal, Khoi Du, Mijung Yim, Betty Lamothe, Nirupama K. Shevde, Hong Ye, Bryant G. Darnay, Hao Wu, Maurizio Cirilli, J. Wesley Pike, Masha Vologodskaia, Takashi Kobayashi, Sujay Singh, Oki K. Dzivenu
Publikováno v:
Nature. 418:443-447
Tumour-necrosis factor (TNF) receptor-associated factor 6 (TRAF6) is the only TRAF family member that participates in signal transduction of both the TNF receptor (TNFR) superfamily and the interleukin-1 receptor (IL-1R)/Toll-like receptor (TLR) supe
Publikováno v:
The Cleft Palate-Craniofacial Journal. 38:606-614
Objective: Nonsyndromic craniosynostosis is characterized by premature closure of one or more cranial sutures in infants. The purpose of this investigation was to evaluate cellular and molecular events that lead to pathogenesis of nonsyndromic cranio