Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Niru Dayal"'
1
Sulfur-related air pollutants induce the generation of platelet-activating factor, 5-lipoxygenase- and cyclooxygenase-products in canine alveolar macrophages via activation of phospholipases A2
Autor: Joachim Heyder, Claudio Denzlinger, C. Haberl, A. Ziesenis, Ingrid Beck-Speier, Konrad Maier, Niru Dayal
Publikováno v: Prostaglandins & Other Lipid Mediators. 71:217-234
Recent studies have shown that long-term in vivo exposure of dogs to neutral sulfur(IV)/sulfite aerosols induces mild inflammatory reactions, whereas the combination of neutral sulfite with acidic sulfur(VI)/sulfate aerosols evokes less pronounced ef
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::884bc6df021a08aa1db7c61fcc30cb41
https://doi.org/10.1016/s1098-8823(03)00041-8
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2
Pro-inflammatory response of alveolar macrophages induced by sulphite: studies with lucigenin-dependent chemiluminescence
Autor: Ingrid Beck-Speier, Konrad Maier, Niru Dayal
Publikováno v: Journal of Bioluminescence and Chemiluminescence. 13:91-99
Alveolar macrophages (AM) were studied for their capability to release mediators involved in modulation of neutrophil (PMN) functions. Initial responses were induced by sulphite. Supernatants obtained from canine, human and rat AM pre-treated with su
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e08b059cf3d227f83109ae32702729c
https://doi.org/10.1002/(sici)1099-1271(199803/04)13:2<91::aid-bio476>3.0.co
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3
Effect of sulphite on the oxidative metabolism of human neutrophils: Studies with lucigenin- and luminol-dependent chemiluminescence
Autor: Anil Mishra, Ingrid Beck-Speier, Niru Dayal
Publikováno v: Journal of Bioluminescence and Chemiluminescence. 10:9-19
To assess the effect of sulphite on the oxidative metabolism of human neutrophils, chemiluminescence (CL) measurements were performed using lucigenin and luminol as chemiluminigenic probes. Lucigenin-dependent CL was used for measuring superoxide ani
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19b34a7f9cb0e490a8db2376403be24
https://doi.org/10.1002/bio.1170100103
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4
Early Response of the Canine Respiratory Tract Following Long-Term Exposure to a Sulfur(IV) Aerosol at low Concentration. II. Biochemistry and Cell Biology of Lung Lavage Fluid
Autor: L. Leuschel, Niru Dayal, A. C. Lenz, L. Ruprecht, H. Hinze, Ingrid Beck-Speier, K.L. Maier, Joachim Heyder, P. Heilmann, U. Miaskowski, E. Matejkova
Publikováno v: Inhalation Toxicology. 4:175-195
Eight beagle dogs were exposed for 290 d to a low concentration of sulfur(IV/) aerosol 10.3 mg m−3 S(IV) corresponding to 0.6 mg m−3 sulfur dioxidel. No clinical symptoms were found that could be correlated with the pollutant. However, significan
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::071a5756e68fb97d8047c85addfe0548
https://doi.org/10.3109/08958379209145667
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5
Soluble iron modulates iron oxide particle-induced inflammatory responses via prostaglandin E2 synthesis: In vitro and in vivo studies
Autor: Paula Mayer, Ingrid Beck-Speier, Urmila P. Kodavanti, Manuela Semmler-Behnke, Mette C. Schladweiler, Niru Dayal, Wolfgang G. Kreyling, K.L. Maier
Publikováno v: Particle and Fibre Toxicology, Vol 6, Iss 1, p 34 (2009)
Particle and Fibre Toxicology
Background Ambient particulate matter (PM)-associated metals have been shown to play an important role in cardiopulmonary health outcomes. To study the modulation of PM-induced inflammation by leached off metals, we investigated intracellular solubil
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dcd72cf2ef916104317de1b070d0897
http://www.particleandfibretoxicology.com/content/6/1/34
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6
Long-term exposure of dogs to a sulphite aerosol: II. Effects on biochemical and cellular lung parameters
Autor: Joachim Heyder, Ingrid Beck-Speier, E. Matjekova, U. Miaskowski, A.-G. Lenz, Niru Dayal, P. Heilmann, L. Leuschel, K.L. Maier, L. Ruprecht, H. Hinze
Publikováno v: Journal of Aerosol Science. 21:S475-S478
During exposure of 8 Beagle dogs for 290 days to particulate sulphur(IV) no clinical symptoms were seen which could be correlated with the pollutant. However, significant changes were observed in some of the biochemical and cellular parameters in the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9510d26ddef0a9fb0f49ad9b920360cf
https://doi.org/10.1016/0021-8502(90)90284-5
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7
Oxymetazoline inhibits proinflammatory reactions: effect on arachidonic acid-derived metabolites
Autor: Manuela Semmler, Ingrid Beck-Speier, Erwin Karg, Gabriele Schumann, Stephan M. Koelsch, Niru Dayal, Konrad Maier
Publikováno v: The Journal of pharmacology and experimental therapeutics. 316(2)
The nasal decongestant oxymetazoline effectively reduces rhinitis symptoms. We hypothesized that oxymetazoline affects arachidonic acid-derived metabolites concerning inflammatory and oxidative stress-dependent reactions. The ability of oxymetazoline
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0e409cb88f3d7631aebaac3d828066
https://pubmed.ncbi.nlm.nih.gov/16221739
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8
Oxidative stress and lipid mediators induced in alveolar macrophages by ultrafine particles
Autor: Wolf Bors, Manuela Semmler, Holger Schulz, Niru Dayal, James M. Samet, Ingrid Beck-Speier, Shinji Takenaka, Joachim Heyder, Erwin Karg, A.J. Ghio, Konrad L. Maier, Gabriele Schumann, Kurt Stettmaier
Publikováno v: Free radical biologymedicine. 38(8)
In ambient aerosols, ultrafine particles (UFP) and their agglomerates are considered to be major factors contributing to adverse health effects. Reactivity of agglomerated UFP of elemental carbon (EC), Printex 90, Printex G, and diesel exhaust partic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d351ce7754b47495ea5f32515f4c4e
https://pubmed.ncbi.nlm.nih.gov/17640559
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10
Agglomerates of Ultrafine Particles of Elemental Carbon and TiO2 Induce Generation of Lipid Mediators in Alveolar Macrophages
Autor: Erwin Karg, Ingrid Beck-Speier, Christa Roth, A. Ziesenis, Niru Dayal, Konrad Maier, Joachim Heyder
Publikováno v: Environ. Health Perspect. 109, Suppl.4, 613-618 (2001)
Environmental Health Perspectives
Agglomerates of ultrafine particles (AUFPs) may cause adverse health effects because of their large surface area. To evaluate physiologic responses of immune cells, we studied whether agglomerates of 77-nm elemental carbon [(EC); specific surface are
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2672acb751566442e3168e125af45219
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=9538
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