Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Niroshani S. Soysa"'
Autor:
Neil Alles, Niroshani S. Soysa
Publikováno v:
Journal of Cellular Biochemistry. 120:6851-6859
In the recent past, there has been a burgeoning interest in targeting cytokines such as IL-3 for specific disease conditions of bone such as rheumatoid arthritis and multiple myeloma. Unlike other cytokines, IL-3 is a cytokine with a multilineage pot
Autor:
Niroshani S. Soysa, Hansani Waidyarathne, Chrisman Neil Roshan Alexander Alles, Madushani Ranaweera
Publikováno v:
Dentistry Review. 1:100006
Publikováno v:
Journal of Investigative and Clinical Dentistry. 10
The aim of the present systematic review and meta-analysis was to address the following Population, Intervention, Comparison, and Outcome question: Is the efficacy of articaine better than lignocaine in adults requiring dental treatment? Four percent
Autor:
Neil Alles, Niroshani S. Soysa
Publikováno v:
Biochemical and Biophysical Research Communications. 476:115-120
Bone resorption is an important cellular function in skeletal development and remodeling of the adult skeleton. Most of the pathological bone disease conditions like osteoporosis reflect increased osteoclast activity; hence, increased bone resorption
Autor:
Niroshani S. Soysa, Neil Alles
Publikováno v:
Bone Reports
Bone Reports, Vol 11, Iss, Pp-(2019)
Bone Reports, Vol 11, Iss, Pp-(2019)
Survival and apoptosis are of major importance in the osteoclast life cycle. As osteoclasts have short lifespan, any alteration that prolongs their viability may cause enhanced osteoclast activity. Hence, the regulation of OC apoptosis has been recog
The local administration of TNF-α and RANKL antagonist peptide promotes BMP-2-induced bone formation
Autor:
Neil Alles, Hisataka Yasuda, Keiichi Ohya, Risako Mikami, Yuriko Furuya, Abdulla Al Masud Khan, Kazuhiro Aoki, Niroshani S. Soysa, Kenichi Nagano, Md. Al Mamun
Publikováno v:
Journal of Oral Biosciences. 55:47-54
Objectives Because high doses of bone morphogenetic proteins (BMPs) are required to achieve a certain level of bone regeneration in primates, thereby causing side effects such as inflammation, combination therapies using BMPs along with agents that c
Autor:
Niroshani S. Soysa, Neil Alles
Publikováno v:
The Journal of Dentists. 4
Introduction: Oral health is an integral part of the overall health. Schism between the mouth and body might be due to the fact that dentistry is not considered typically as part of the medical system and lack of interest by the physicians towards de
Publikováno v:
Journal of Periodontal Research. 46:280-284
Soysa NS, Alles N, Takahashi M, Aoki K, Ohya K. Defective nuclear factor-κB-inducing kinase in aly/aly mice prevents bone resorption induced by local injection of lipopolysaccharide. J Periodont Res 2011; 46: 280–284. © 2010 John Wiley & Sons A/S
Publikováno v:
Brazilian Journal of Oral Sciences, Vol 17 (2018)
According to the best scientific evidence, a dentifrice should contain 1000 ppm F or above but to guarantee the anti-caries efficacy this concentration should be chemically soluble and remain stable until the dentifrice expiration date. This stabilit
Autor:
Asako Shimoda, Kazunari Akiyoshi, Kazuhiro Aoki, Juri Hayashi, Olaf Ritzeler, Hitoyata Shimokawa, Niroshani S. Soysa, Masud Khan, Neil Alles, Keiichi Ohya
Publikováno v:
Endocrinology. 151:4626-4634
Bone degenerative diseases, including osteoporosis, impair the fine balance between osteoclast bone resorption and osteoblast bone formation. Single-agent therapy for anabolic and anticatabolic effects is attractive as a drug target to ameliorate suc