Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nirmeen Elmadany"'
Autor:
Leonard D. Kuhrt, Edyta Motta, Nirmeen Elmadany, Hannah Weidling, Raphaela Fritsche-Guenther, Ibrahim E. Efe, Olivia Cobb, Jit Chatterjee, Lucy G. Boggs, Marina Schnauß, Sebastian Diecke, Marcus Semtner, Corina Anastasaki, David H. Gutmann, Helmut Kettenmann
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 12 (2023)
Externí odkaz:
https://doaj.org/article/27ffcc79016247599283cd70ac5c43af
Autor:
Michael Platten, Julius Michel, Khwab Sanghvi, Kristine Jähne, Michael Breckwoldt, Katharina Sahm, Nirmeen Elmadany, Jana Sonner, Svetlana Ovchinnikova, Isabelle Bernhardt, Xin-Wen Zhang, Ankita Sati, Simon Anders
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/24f42edede9947549c87d4b5bd34c655
Autor:
Rienk Offringa, Ralf Lesche, Iris Oezen, Michael Platten, Daniel Baumann, Christiane A Opitz, Ahmed Sadik, Catherine Olesch, Frederik Cichon, Norbert Schmees, Ulrike Roehn, Florian Prinz, Detlef Stoeckigt, Katharina Sahm, Nirmeen Elmadany, Christina Kober, Julian Roewe, Lars Roese, Benjamin Bader, Mátyás Gorjánácz, Helge Gottfried Roider, Gabriele Leder, Horst Irlbacher, Julien Lefranc, Mine Oezcan-Wahlbrink, Ankita Sati Batra, Rafael Carretero, Hilmar Weinmann, Ingo V Hartung, Bertolt Kreft, Ilona Gutcher
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 11 (2023)
Background The metabolism of tryptophan to kynurenines (KYN) by indoleamine-2,3-dioxygenase or tryptophan-2,3-dioxygenase is a key pathway of constitutive and adaptive tumor immune resistance. The immunosuppressive effects of KYN in the tumor microen
Externí odkaz:
https://doaj.org/article/bc1e59d7b2b148a6869f255df5b9d454
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1738 (2022)
Immunotherapy has revolutionized cancer treatment. Despite the recent advances in immunotherapeutic approaches for several tumor entities, limited response has been observed in malignant gliomas, including glioblastoma (GBM). Conversely, one of the e
Externí odkaz:
https://doaj.org/article/45bb697b7ed54e13a2b9b8a6876044af
Autor:
Nirmeen Elmadany, Francesca Logiacco, Alice Buonfiglioli, Verena C. Haage, Elizabeth C. Wright-Jin, Alexander Schattenberg, Roxane M. Papawassiliou, Helmut Kettenmann, Marcus Semtner, David H. Gutmann
Publikováno v:
Neurobiology of Disease, Vol 144, Iss , Pp 105030- (2020)
As critical regulators of brain homeostasis, microglia are influenced by numerous factors, including sex and genetic mutations. To study the impact of these factors on microglia biology, we employed genetically engineered mice that model Neurofibroma
Externí odkaz:
https://doaj.org/article/9e0770fe1b7e43c2bbca4f9a3728af3b
Publikováno v:
Molecular Pharmacology. 98:559-576
The Notch family consists of four highly conserved transmembrane receptors. The release of the active intracellular domain requires the enzymatic activity of γ-secretase. Notch is involved in embryonic development and in many physiologic processes o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb5d680cbdfc6cfa0442afea127cde6
https://doi.org/10.1124/molpharm.120.000006
https://doi.org/10.1124/molpharm.120.000006
Autor:
Rana Abu-Dahab, Nirmeen Elmadany, Enam A. Khalil, Ibraheem Yousef, Giovanni Birarda, Lisa Vaccari
Publikováno v:
Infrared Physics & Technology. 95:141-147
Breast cancer is the most common type of cancer among females worldwide. Doxorubicin (Dox) is one of the main chemotherapy drugs used in neoadjuvant and adjuvant breast cancer therapy. Dox-induced cardiotoxicity limits its use to a definite period an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ba175ab7425dca22c5fff6de61e0605
https://doi.org/10.1016/j.infrared.2018.10.014
https://doi.org/10.1016/j.infrared.2018.10.014
Autor:
Verena Haage, Stefan Wendt, Helmut Kettenmann, Nirmeen Elmadany, Josien Visser, Philipp Mertins, Dolores Hambardzumyan, Daniel Hernández, Marcus Semtner, Francesca Logiacco, Felipe de Almeida Sassi, Susanne A. Wolf
Publikováno v:
J Neurosci
Microglial cells are considered as sensors of brain pathology by detecting any sign of brain lesions, infections, or dysfunction and can influence the onset and progression of neurological diseases. They are capable of sensing their neuronal environm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a839b8a2f3e7b7be142a853c7bddc4
https://pubmed.ncbi.nlm.nih.gov/32060170
https://pubmed.ncbi.nlm.nih.gov/32060170
Autor:
Verena Haage, Nirmeen Elmadany, Andreas Faissner, David H. Gutmann, Helmut Kettenmann, Lars Roll, Marcus Semtner
Publikováno v:
Brain, behavior, and immunity. 81
Tenascin C (Tnc) is an extracellular matrix glycoprotein, expressed in the CNS during development, as well as in the setting of inflammation, fibrosis and cancer, which operates as an activator of Toll-like receptor 4 (TLR4). Although TLR4 is highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b663a6bc151837efb238517d849093
https://pubmed.ncbi.nlm.nih.gov/31271872
https://pubmed.ncbi.nlm.nih.gov/31271872