Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Nirmalya Pradhan"'
Autor:
Niku Moni Das, Biswa Mohan Prusty, Nirmalya Pradhan, Anjali Gupta, Miguel Carmena-Bargueño, Rama Karn, Horacio Pérez-Sánchez, Sachin Kumar, Debasis Manna
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 9, Iss , Pp 100110- (2023)
Herein, we report the development of synthetically simpler analogs of 4,7-dichloroquinoline (DCQ) as apo-indoleamine 2,3-dioxygenase 1(IDO1) protein targeting ligand to inhibit the activity of IDO1 enzyme. Derivatization of the DCQ moiety improved th
Externí odkaz:
https://doaj.org/article/260796f6cd1e40078b733e1f62ca1d07
Publikováno v:
Pediatric Hematology Oncology Journal, Vol 7, Iss 4, Pp S50- (2022)
Externí odkaz:
https://doaj.org/article/4be3bd0ea9664cada9ef8baa4eeabe19
Publikováno v:
Pediatric Hematology Oncology Journal, Vol 1, Iss 2, p S9 (2016)
Externí odkaz:
https://doaj.org/article/0a991961b5fa4575b86d35cc43b2577e
Autor:
Khyati Raina, Rajkumar P. Thummer, Debasis Manna, Nirmalya Pradhan, Anjali Patel, Oindrila Biswas, Subhasis Dey
Publikováno v:
Chemical Communications. 56:1661-1664
We describe a novel class of stimuli-sensitive sulfonium-based synthetic lipids, which exhibit several favorable biophysical properties of phospholipids. The potent sulfonium-based lipid was successfully disassembled by glutathione to release the enc
Autor:
Abhishek Saha, Nirmalya Pradhan, Subhankar Panda, Arindam Bhattacharyya, Soumya Chatterjee, Sudhir Morla, Ashalata Roy, Sachin Kumar, Debasis Manna
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific Reports
Scientific Reports
The improvement of body’s own immune system is considered one of the safest approaches to fight against cancer and several other diseases. Excessive catabolism of the essential amino acid, L-tryptophan (L-Trp) assists the cancer cells to escape nor
Autor:
Sumeet Gujral, Maya Prasad, Shripad Banavali, Seema Kembhavi, Nirmalya Pradhan, Gaurav Narula, Tanuja Shet, Sneha Shah, Epari Sridhar, Deepa S Joy Phillip, Kalasekhar Vijayasekharan
Publikováno v:
Leukemia & Lymphoma. 61:912-918
Anaplastic large cell lymphoma (ALCL) is a rare form of non-Hodgkin lymphoma (NHL) in children. Most treatment regimens include high-dose methotrexate (HDMTX), which is logistically difficult to administer in resource-limited settings. We evaluated t
Autor:
Abhishek Saha, Nirmalya Pradhan, Vishal Trivedi, Arindam Bhattacharyya, Debasis Manna, Rakesh Kumar Singh, Soumya Chatterjee
Publikováno v:
ACS Applied Nano Materials. 2:3671-3683
Protein-based nanostructures have reformed nanoscience and nanotechnology on account of their smaller sizes and greater surface areas, which instigate their interactions with other molecules. The p...
Autor:
Debasis Manna, M. T. Shah, Nasim Akhtar, Nirmalya Pradhan, Sachin Kumar, Oindrila Biswas, Subhasis Dey, Vishnu Kumar, Abhishek Saha
Publikováno v:
Chemical Communications. 55:8482-8485
A stimuli-responsive anion transport strategy was successfully employed to regulate the water solubility of ionophores and promote controlled transport of Cl- ions across lipid bilayers. A sulfonium-based proanionophore was efficiently activated by g
Autor:
Arindam Bhattacharyya, Diship Srivastava, Subhasis Dey, Debasis Manna, Soumya Chatterjee, Nirmalya Pradhan, Anjali Patel, Niladri Patra
Publikováno v:
Chemical communications (Cambridge, England). 57(38)
We developed NIR-light-responsive macrocyclic cationic gemini amphiphiles, one of which displayed various favorable properties of lipids. The NIR-light-mediated cleavage of the strained dioxacycloundecine ring led to the conversion of the spherical t
Autor:
Abhishek Saha, Soumya Chatterjee, Priyadarshi Satpati, Nirmalya Pradhan, Suvankar Ghosh, Manas Kumar Santra, Debasis Manna, Ganesh Kumar Barik, Arindam Bhattacharyya, Nasim Akhtar
Publikováno v:
ACS applied materialsinterfaces. 12(23)
Synthetic ion transporters have attracted tremendous attention for their therapeutic potential against various ion-transport-related diseases, including cancer. Inspired by the structure and biological activities of natural products, we synthesized a